Csf2ra^em1Szut
Endonuclease-mediated Allele Detail

Summary

• Symbol: Csf2ra^em1Szut
• Name: colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage); endonuclease-mediated mutation 1, Suzuki Takuji
• MGI ID: MGI:7261176
• Synonyms: Csf2ra^{- line 7169}
• Gene: Csf2ra Location: Chr19:61212395-61216867 bp, - strand Genetic Position: Chr19, 56.89 cM, cytoband D2
• Alliance: Csf2ra^em1Szut page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 2 and 3 deleted 162 bp (inframe). (J:322934)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Csf2ra Mutation: 22 strains or lines available

References

• Original: J:322934 Shima K, et al., A murine model of hereditary pulmonary alveolar proteinosis caused by homozygous Csf2ra gene disruption. Am J Physiol Lung Cell Mol Physiol. 2022 Mar 1;322(3):L438-L448
• All: 1 reference(s)