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DccTg(H2-Kb-Jak2*V617F)1Shmd
Transgenic Allele Detail
Summary
Symbol: DccTg(H2-Kb-Jak2*V617F)1Shmd
Name: deleted in colorectal carcinoma; transgene insertion 1, Kazuya Shimoda
MGI ID: MGI:5444031
Synonyms: JAK2 V617F
Gene: Dcc  Location: Chr18:71386705-72484140 bp, - strand  Genetic Position: Chr18, 45.24 cM
Alliance: DccTg(H2-Kb-Jak2*V617F)1Shmd page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
DccTg(H2-Kb-Jak2*V617F)1Shmd expresses 1 gene
 
Mutation detailsThis transgene consists of murine Jak2 with a phenylalanine for valine substitution at residue 617 under the control of the H-2Kb promoter. The transgene integrated in intron 12 of Dcc in this line. (J:130189)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dcc Mutation:  76 strains or lines available
References
Original:  J:130189 Shide K, et al., Development of ET, primary myelofibrosis and PV in mice expressing JAK2 V617F. Leukemia. 2008 Jan;22(1):87-95
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory