Id3^tm2.1Cmu
Targeted Allele Detail

Summary

• Symbol: Id3^tm2.1Cmu
• Name: inhibitor of DNA binding 3; targeted mutation 2.1, Cornelis Murre
• MGI ID: MGI:5305600
• Synonyms: Id3^G, Id3^gfp, Id3-GFP
• Gene: Id3 Location: Chr4:135871133-135872703 bp, + strand Genetic Position: Chr4, 68.34 cM
• Alliance: Id3^tm2.1Cmu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:176462
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted upstream of a modified exon 1 in which a GFP and stop sequence was inserted at the translation initiation site. Cre-mediated recombination removed the neo cassette. (J:176462)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Id3 Mutation: 16 strains or lines available

References

• Original: J:176462 Miyazaki M, et al., The opposing roles of the transcription factor E2A and its antagonist Id3 that orchestrate and enforce the naive fate of T cells. Nat Immunol. 2011;12(10):992-1001
• All: 15 reference(s)