Cd83^tm1.1Lnjt
Targeted Allele Detail

Summary

• Symbol: Cd83^tm1.1Lnjt
• Name: CD83 antigen; targeted mutation 1.1, Lars Nitschke
• MGI ID: MGI:5819103
• Synonyms: cd83^fl
• Gene: Cd83 Location: Chr13:43938588-43956609 bp, + strand Genetic Position: Chr13, 21.6 cM, cytoband A4-5
• Alliance: Cd83^tm1.1Lnjt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238327
• Parent Cell Line: JM8A3 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 1 and 2 of the gene were flanked with two loxP sites. The frt-flanked neomycin resistance cassette was removed by mating to Flp recombinase expressing mice. (J:238327)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd83 Mutation: 15 strains or lines available

References

• Original: J:238327 Krzyzak L, et al., CD83 Modulates B Cell Activation and Germinal Center Responses. J Immunol. 2016 May 01;196(9):3581-94
• All: 3 reference(s)