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Transgene Detail
Symbol: Tg(KRT5-rtTA)#Glk
Name: transgene insertion, Adam Glick
MGI ID: MGI:4867436
Synonyms: K5-tTA
Transgene: Tg(KRT5-rtTA)#Glk  Location: unknown  
Alliance: Tg(KRT5-rtTA)#Glk page
Strain of Origin:  FVB/N
Transgene Type:    Transgenic (Transactivator)
Mutation:    Insertion
Mutation detailsThis transgene contains the reverse tetracycline-regulated transactivator gene rtTA under control of the bovine keratin 5 promoter. The rtTA coding sequence lies downstream of approximately 5.2 kilobases of DNA from the 5' flanking region of the keratin followed by a beta-globin intron and upstream of an SV40 polyadenylation signal. Eleven lines were generated. The pound symbol (#) is used to denote when no line is psecified or multiple lines are pooled. (J:65791)
View phenotypes and curated references for all genotypes (concatenated display).
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Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Original:  J:65791 Diamond I, et al., Conditional gene expression in the epidermis of transgenic mice using the tetracycline-regulated transactivators tTA and rTA linked to the keratin 5 promoter. J Invest Dermatol. 2000 Nov;115(5):788-94
All:  59 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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MGI 6.22
The Jackson Laboratory