Ciao2b^{em1(IMPC)Ccpcz}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ciao2b^{em1(IMPC)Ccpcz}
• Name: cytosolic iron-sulfur assembly component 2B; endonuclease-mediated mutation 1, Institute of Molecular Genetics
• MGI ID: MGI:6341859
• Gene: Ciao2b Location: Chr8:105366471-105368360 bp, - strand Genetic Position: Chr8, 53.04 cM, cytoband D1
• Alliance: Ciao2b^{em1(IMPC)Ccpcz} page
• IMPC: Ciao2b gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Deletion
• Mutation details: This allele was generated at Czech Centre for Phenogenomics using Cas9 and guides with spacer sequences GAAGCGGTGTATTTGTCGTG and GAGAGACGCTAAGGCATACT that targeted exon(s) ENSMUSE00000372231.6 ENSMUSE00000580593.5 ENSMUSE00000899253.2 ENSMUSE00000916629.2 ENSMUSE00001265486.2 ENSMUSE00001292742.2 ENSMUSE00001304669.2 ENSMUSE00001604000.1 ENSMUSE00001862848.1 ENSMUSE00001862851.1 ENSMUSE00001862852.1 ENSMUSE00002179351.1 ENSMUSE00002179352.1. This resulted in deletion(s) of 2056 bp (location: Chr8:105366468-105368523; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ciao2b Mutation: 12 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 4 reference(s)