Rtl6^tm2.1Tmki
Targeted Allele Detail

Summary

• Symbol: Rtl6^tm2.1Tmki
• Name: retrotransposon Gag like 6; targeted mutation 2.1, Tomoko Kaneko-Ishino
• MGI ID: MGI:7378509
• Synonyms: Rtl6 MT
• Gene: Rtl6 Location: Chr15:84437599-84442024 bp, - strand Genetic Position: Chr15, 39.88 cM
• Alliance: Rtl6^tm2.1Tmki page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:329352
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct replaced the coding region with an FRT and loxP site following recombination. (J:329352)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rtl6 Mutation: 8 strains or lines available

References

• Original: J:329352 Irie M, et al., Retrovirus-derived RTL5 and RTL6 genes are novel constituents of the innate immune system in the eutherian brain. Development. 2022 Sep 15;149(18):dev200976
• All: 2 reference(s)