About   Help   FAQ
Rtl6 Gene Detail
Summary
  • Symbol
    Rtl6
  • Name
    retrotransposon Gag like 6
  • Synonyms
    Ldoc1l, Mar6, Mart6, MGC:73499
  • Feature Type
    protein coding gene
  • IDs
    MGI:2675858
    NCBI Gene: 223732
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:84437599-84442024 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 39.88 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    69 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2675858
 protein coding gene Chr15:84437599-84442024 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022179
 protein coding gene Chr15:85357226-85361647 (-)
A/J MGP_AJ_G0022138
 protein coding gene Chr15:82200211-82204631 (-)
AKR/J MGP_AKRJ_G0022113
 protein coding gene Chr15:84602475-84606896 (-)
BALB/cJ MGP_BALBcJ_G0022144
 protein coding gene Chr15:82333564-82337984 (-)
C3H/HeJ MGP_C3HHeJ_G0021914
 protein coding gene Chr15:84560068-84564488 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022589
 protein coding gene Chr15:88601488-88605913 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020114
 protein coding gene Chr15:78551678-78556079 (-)
CAST/EiJ MGP_CASTEiJ_G0021436
 protein coding gene Chr15:85354218-85358639 (-)
CBA/J MGP_CBAJ_G0021881
 protein coding gene Chr15:91476114-91480534 (-)
DBA/2J MGP_DBA2J_G0022008
 protein coding gene Chr15:81673462-81677882 (-)
FVB/NJ MGP_FVBNJ_G0021987
 protein coding gene Chr15:80727184-80731605 (-)
LP/J MGP_LPJ_G0022079
 protein coding gene Chr15:85510512-85514933 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022007
 protein coding gene Chr15:96275885-96280305 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022604
 protein coding gene Chr15:84613893-84618313 (-)
PWK/PhJ MGP_PWKPhJ_G0021177
 protein coding gene Chr15:81682029-81686419 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021011
 protein coding gene Chr15:84328155-84332526 (-)
WSB/EiJ MGP_WSBEiJ_G0021485
 protein coding gene Chr15:85113871-85118292 (-)



Homology
more
  • Human Ortholog
    RTL6, retrotransposon Gag like 6
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RTL6, retrotransposon Gag like 6
  • Synonyms
    dJ1033E15.2, LDOC1L, Mar6, Mart6, SIRH3
  • Links
    NCBI Gene ID: 84247
    neXtProt AC: NX_Q6ICC9
    UniProt: Q6ICC9

  • Chr Location
    22q13.31; chr22:44492583-44498233 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from multigenic genotypes
    24 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    3 involving Rtl6
  • Find Mice (IMSR)
    8 strains or lines available
Mice homozygous for a null allele exhibit impaired LPS removal.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    941
  • Tissues
    63
  • cDNA Data
    83
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 223732 NCBI Gene Model | MGI Sequence Detail 4426 C57BL/6J ±  kb
transcript NM_177630 RefSeq | MGI Sequence Detail 4426 C57BL/6  
polypeptide Q505G4 UniProt | EBI | MGI Sequence Detail 243 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 86
    Genomic 1
    cDNA 83
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 46
    Developmental Gene Expression 4
    Diseases 1
    Phenotypes 24
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:343808 Ishino F, et al., Retrovirus-Derived RTL9 Plays an Important Role in Innate Antifungal Immunity in the Eutherian Brain. Int J Mol Sci. 2023 Oct 4;24(19)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory