Tg(Pcp2-cre)2Mpin
Transgene Detail
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Symbol: |
Tg(Pcp2-cre)2Mpin |
Name: |
transgene insertion 2, Max-Planck-Institute of Neurobiology |
MGI ID: |
MGI:2137515 |
Synonyms: |
L7-cre, L7Cre-2, pcp2Cre-2 |
Transgene: |
Tg(Pcp2-cre)2Mpin Location: unknown
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Alliance: |
Tg(Pcp2-cre)2Mpin page
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Purkinje cell degeneration in Afg3l2tm1Arte/Afg3l2tm1Arte Tg(Pcp2-cre)2Mpin/0 mice
Show the 7 phenotype image(s) involving this allele.
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Transgene Type: |
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Transgenic (Recombinase) |
Mutation: |
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Insertion
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Tg(Pcp2-cre)2Mpin expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
Not Specified |
Pcp2 |
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Mutation details: These transgenic mice express Cre recombinase under the direction of the Purkinje cell-specific L7/Pcp2 promoter. Recombinase activity is observed in most Purkinje cells and some retinal bipolar neurons. Small amounts of activity are observed in an unidentified population of cells of the central nervous system tissue. Recombination is first observed around postnatal day 6 and is fully established 2 to 3 weeks after birth.
(J:66884)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Pcp2
(species not specified)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:66884 Barski JJ, et al., Cre recombinase expression in cerebellar purkinje cells. Genesis. 2000 Nov-Dec;28(3-4):93-8 |
All: |
184 reference(s) |
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