Nek7^M1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Nek7^M1Btlr
• Name: NIMA (never in mitosis gene a)-related expressed kinase 7; mutation 1, Bruce Beutler
• MGI ID: MGI:5690178
• Synonyms: Cuties, Nek7^Cu
• Gene: Nek7 Location: Chr1:138411575-138547481 bp, - strand Genetic Position: Chr1, 60.82 cM
• Alliance: Nek7^M1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to A transversion at base pair 138,544,242 (v38) on chromosome 1, or base pair 75,538 in the GenBank genomic region NC_000067, corresponding to residue 332 in exon 3 of 10 total exons. The mutation results in a substitution of cysteine (C) to a premature stop codon at residue 53. (J:225042)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nek7 Mutation: 39 strains or lines available

References

• Original: J:225042 Shi H, et al., Mutagenetix entry for Cuties. MGI Direct Data Submission. 2015
• All: 2 reference(s)