Appl1^Gt(XM073)Byg
Gene trapped Allele Detail

Summary

• Symbol: Appl1^Gt(XM073)Byg
• Name: adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1; gene trap XM073, BayGenomics
• MGI ID: MGI:4128359
• Synonyms: xmo73
• Gene: Appl1 Location: Chr14:26640943-26692567 bp, - strand Genetic Position: Chr14, 16.09 cM, cytoband B
• Alliance: Appl1^Gt(XM073)Byg page

Mutation origin

• Mutant Cell Line: XM073
• Germline Transmission: Earliest citation of germline transmission: J:164696
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0Lxf Vector Type: gene trap
• The gene trap vector disrupts exon 1. The absence of transcript was confirmed by RT-PCR. (J:164696)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XM073	CC325143 ; (MGI Seq Detail)	5' RACE	Chr14:26692360-26692422 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  8 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:

130 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Appl1 Mutation: 45 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)