Pi4ka^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Pi4ka^m1Btlr
• Name: phosphatidylinositol 4-kinase alpha; mutation 1, Bruce Beutler
• MGI ID: MGI:6200379
• Synonyms: pia
• Gene: Pi4ka Location: Chr16:17098215-17224178 bp, - strand Genetic Position: Chr16, 10.71 cM
• Alliance: Pi4ka^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced G to A transition at base pair 17,281,044 (v38) on chromosome 16, or base pair 125,271 in the GenBank genomic region NC_000082 encoding Pi4ka. The mutation corresponds to residue 6,053 in the mRNA sequence NM_001001983 within exon 53 of 55 total exons. The mutation results in an arginine (R) to histidine (H) substitution at position 1,992 (R1992H) in the PI4KA protein. (J:265261)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pi4ka Mutation: 126 strains or lines available

References

• Original: J:265261 Ochoa C, et al., Mutagenetix entry for pia. MGI Direct Data Submission. 2018
• All: 1 reference(s)