Tg(DPP4)2Nnag
Transgene Detail

Summary

• Symbol: Tg(DPP4)2Nnag
• Name: transgene insertion 2, Noriyo Nagata
• MGI ID: MGI:6403115
• Synonyms: Tg2
• Transgene: Tg(DPP4)2Nnag Location: unknown
• Alliance: Tg(DPP4)2Nnag page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA)F1 x C57BL/6NCr

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(DPP4)2Nnag expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  DPP4 (1803)

  Dpp4	(MGI:94919)

• Mutation details: This transgene consists of a BAC clone (RP11-345J9) containing the complete human DPP4 gene and the endogenous promoter. Two lines (1 and 2) were generated. Line 2 shows higher transgene expression than line 1. (J:286321)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:286321 Iwata-Yoshikawa N, et al., Acute Respiratory Infection in Human Dipeptidyl Peptidase 4-Transgenic Mice Infected with Middle East Respiratory Syndrome Coronavirus. J Virol. 2019 Mar 15;93(6)
• All: 5 reference(s)