Fbxo21^em1Smbk
Endonuclease-mediated Allele Detail

Summary

• Symbol: Fbxo21^em1Smbk
• Name: F-box protein 21; endonuclease-mediated mutation 1, Shannon M Buckley
• MGI ID: MGI:7444787
• Synonyms: Fbxo21^f
• Gene: Fbxo21 Location: Chr5:118114835-118148263 bp, + strand Genetic Position: Chr5, 57.73 cM
• Alliance: Fbxo21^em1Smbk page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exons 5 and 6. (J:333469)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fbxo21 Mutation: 40 strains or lines available

References

• Original: J:333469 Wittorf KJ, et al., Ubiquitin E3 ligase FBXO21 regulates cytokine-mediated signaling pathways, but is dispensable for steady-state hematopoiesis. Exp Hematol. 2022 Oct;114:33-42.e3
• All: 1 reference(s)