Siglecg^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Siglecg^m2Btlr
• Name: sialic acid binding Ig-like lectin G; mutation 2, Bruce Beutler
• MGI ID: MGI:6200066
• Synonyms: shenandoah2
• Gene: Siglecg Location: Chr7:43057623-43067773 bp, + strand Genetic Position: Chr7, 28.25 cM
• Alliance: Siglecg^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to A transversion at base pair 43,412,017 (v38) on chromosome 7, or base pair 3,825 in the GenBank genomic region NC_000073. The mutation corresponds to residue 1,588 in the mRNA sequence NM_172900 within exon 9 of 12 total exons. The mutation results in an asparagine to lysine substitution at position 481 (N481K) in the Siglec-G protein. (J:265183)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Siglecg Mutation: 41 strains or lines available

References

• Original: J:265183 Choi JH, et al., Mutagenetix entry for shenandoah2. MGI Direct Data Submission. 2018
• All: 1 reference(s)