Klrc1^tm1Mmka
Targeted Allele Detail

Summary

• Symbol: Klrc1^tm1Mmka
• Name: killer cell lectin-like receptor subfamily C, member 1; targeted mutation 1, Mitsuo Matsuoka
• MGI ID: MGI:5751068
• Gene: Klrc1 Location: Chr6:129642978-129655936 bp, - strand Genetic Position: Chr6, 63.44 cM, cytoband G1-2
• Alliance: Klrc1^tm1Mmka page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222503
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance cassette replaced exons 1 and 2 (as well as part of exon 3). (J:222503)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klrc1 Mutation: 12 strains or lines available

References

• Original: J:222503 Ely KH, et al., Tissue-protective effects of NKG2A in immune-mediated clearance of virus infection. PLoS One. 2014;9(9):e108385
• All: 1 reference(s)