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Targeted Allele Detail
Symbol: Ephb6tm1Tom
Name: Eph receptor B6; targeted mutation 1, Toshimitsu Matsui
MGI ID: MGI:2389310
Gene: Ephb6  Location: Chr6:41582416-41597443 bp, + strand  Genetic Position: Chr6, 19.77 cM
Alliance: Ephb6tm1Tom page
Germline Transmission:  Earliest citation of germline transmission: J:79747
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA portion of exon 1 and all of exons 2 and 3 were replaced by a floxed neo cassette inserted by homologous recombination. The deleted region included the translational start codon. (J:79747)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ephb6 Mutation:  54 strains or lines available
Original:  J:79747 Shimoyama M, et al., Developmental expression of EphB6 in the thymus: lessons from EphB6 knockout mice. Biochem Biophys Res Commun. 2002 Oct 18;298(1):87
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.23
The Jackson Laboratory