Clec4f^tm1Ymed
Targeted Allele Detail

Summary

• Symbol: Clec4f^tm1Ymed
• Name: C-type lectin domain family 4, member f; targeted mutation 1, Yang-Ming University Institute of Clinical Medicine
• MGI ID: MGI:5529277
• Gene: Clec4f Location: Chr6:83621524-83633098 bp, - strand Genetic Position: Chr6, 35.94 cM
• Alliance: Clec4f^tm1Ymed page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:203199
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

Allele Type: Targeted (Null/knockout, Reporter) Mutations: Insertion, Intragenic deletion Mutation details: Most of exon 4 was replaced with a EGFP, polyadenylation sequence and floxed neomycin resistance cassette. Western blot analysis confirmed the absence of protein expression in the liver. (J:203199)

Generation of the Clec4f^tm1Ymed allele

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clec4f Mutation: 28 strains or lines available

References

• Original: J:203199 Yang CY, et al., CLEC4F is an inducible C-type lectin in F4/80-positive cells and is involved in alpha-galactosylceramide presentation in liver. PLoS One. 2013;8(6):e65070
• All: 1 reference(s)