Tg(Ncr1-icre)265Sxl
Transgene Detail
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Symbol: |
Tg(Ncr1-icre)265Sxl |
Name: |
transgene insertion 265, Veronika Sexl |
MGI ID: |
MGI:4941472 |
Synonyms: |
Ncr1-iCreTg |
Transgene: |
Tg(Ncr1-icre)265Sxl Location: unknown
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Alliance: |
Tg(Ncr1-icre)265Sxl page
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Transgene Type: |
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Transgenic (Recombinase) |
Mutation: |
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Insertion
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Tg(Ncr1-icre)265Sxl expression driven by
1 gene
Transgene expression driven by:
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Mutation details: A cassette containing codon-improved cre recombinase (icre), an artificial intron, a bovine growth hormone polyadenylation signal, and an ampicillin-resistance gene flanked by FRT sites was recombined into the first exon of the Ncr1 gene contained in BAC RP23-267N11. Recombined BACs were electroporated with a plasmid expressing Flp to delete the ampicillin gene. The final construct was purified and injected into pronuclei of C57BL/6N oocytes. 4 founders (264-267) were generated with 3 demonstrating transgene expression. Line 265 was selected for detailed analysis.
(J:169574)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Ncr1
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:169574 Eckelhart E, et al., A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development. Blood. 2011 Feb 3;117(5):1565-73 |
All: |
25 reference(s) |
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