Usp45^em1(IMPC)H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Usp45^em1(IMPC)H
• Name: ubiquitin specific petidase 45; endonuclease-mediated mutation 1, Harwell
• MGI ID: MGI:5693168
• Gene: Usp45 Location: Chr4:21767161-21837872 bp, + strand Genetic Position: Chr4, 8.93 cM
• Alliance: Usp45^em1(IMPC)H page
• IMPC: Usp45 gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Medical Research Council Harwell using Cas9 and guides with spacer sequences TCAGTGAGTGAGGCACCTAC and TGGCGCGTAGGCAAGTCTGT that targeted exon(s) ENSMUSE00001305664.2. This resulted in deletion(s) of 512 bp (location: Chr4:21781576-21782087; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Usp45 Mutation: 52 strains or lines available

References

• Original: J:90559 The Mammalian Genetics Unit at Harwell, Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK. Unpublished. 2004-2013
• All: 4 reference(s)