C4bp^tm1Raw
Targeted Allele Detail

Summary

• Symbol: C4bp^tm1Raw
• Name: complement component 4 binding protein; targeted mutation 1, Rick A Wetsel
• MGI ID: MGI:7414030
• Gene: C4bp Location: Chr1:130563658-130589394 bp, - strand Genetic Position: Chr1, 56.89 cM
• Alliance: C4bp^tm1Raw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:332283
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The targeting construct replaced the exons encoding Zp3r, C4bp, and Rbms2 with a neomycin resistance cassette. (J:332283)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any C4bp Mutation: 36 strains or lines available

Notes

ES cells = EZ-1 (129)

References

• Original: J:332283 Nonaka MI, et al., Epididymal C4b-binding protein is processed and degraded during transit through the duct and is not essential for fertility. Immunobiology. 2015 Apr;220(4):467-75
• All: 4 reference(s)