Sgpl1Gt(OST58278)Lex
Gene trapped Allele Detail
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Symbol: |
Sgpl1Gt(OST58278)Lex |
Name: |
sphingosine phosphate lyase 1; gene trap OST58278, Lexicon Genetics |
MGI ID: |
MGI:3833931 |
Synonyms: |
S1PL- |
Gene: |
Sgpl1 Location: Chr10:60934421-60983463 bp, - strand Genetic Position: Chr10, 32.14 cM
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Alliance: |
Sgpl1Gt(OST58278)Lex page
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Thymus abnormalities in Sgpl1Gt(OST58278)Lex/Sgpl1Gt(OST58278)Lex, Sgpl1tm1(SGPL1)Lex/Sgpl1tm1(SGPL1)Lex and Sgpl1tm1(SGPL1)Lex/Sgpl1Gt(OST58278)Lex mice
Show the 6 phenotype image(s) involving this allele.
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Mutant Cell Line: |
OST58278 |
Germline Transmission: |
Earliest citation of germline transmission:
J:145159
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Parent Cell Line: |
Lex-1 (ES Cell)
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Strain of Origin: |
129S5/SvEvBrd
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Project Collection: |
Lexicon
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Allele Type: |
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Gene trapped (Null/knockout) |
Mutation: |
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Insertion of gene trap vector
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Mutation details: The gene trap vector containing a beta-geo cassette was inserted downstream of exon 2. The absence of functional protein was confirmed by enzymatic assay and spleen extracts.
(J:145159)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Sgpl1 Mutation: |
33 strains or lines available
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Original: |
J:145159 Vogel P, et al., Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions. PLoS One. 2009;4(1):e4112 |
All: |
10 reference(s) |
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