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Ergtm1.1Iwamo
Targeted Allele Detail
Summary
Symbol: Ergtm1.1Iwamo
Name: ETS transcription factor; targeted mutation 1.1, Masahiro Iwamoto
MGI ID: MGI:5910506
Synonyms: Ergflox
Gene: Erg  Location: Chr16:95160028-95387452 bp, - strand  Genetic Position: Chr16, 56.04 cM
Alliance: Ergtm1.1Iwamo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:243715
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe targeting vector contains an FRT-flanked neomycin cassette followed by a loxP site upstream of exon 6 and a second loxP site downstream of exon 6. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:243715)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Erg Mutation:  27 strains or lines available
References
Original:  J:243715 Ohta Y, et al., Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg. Arthritis Rheumatol. 2015 Oct;67(10):2679-90
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory