Ebf1^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ebf1^m2Btlr
• Name: early B cell factor 1; mutation 2, Bruce Beutler
• MGI ID: MGI:6199990
• Synonyms: oregano
• Gene: Ebf1 Location: Chr11:44508144-44898918 bp, + strand Genetic Position: Chr11, 26.45 cM
• Alliance: Ebf1^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 44,869,169 (v38) on chromosome 11, or base pair 251,070 in the GenBank genomic region NC_000077 encoding Ebf1. The mutation corresponds to residue 711 in the mRNA sequence NM_007897 within exon 7 of 16 total exons. The mutation results in substitution of phenylalanine 211 for a serine (F211S) in all variants of the EBF1 protein. (J:265158)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ebf1 Mutation: 73 strains or lines available

References

• Original: J:265158 Choi JH, et al., Mutagenetix entry for oregano. MGI Direct Data Submission. 2018
• All: 1 reference(s)