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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ebf1m2Btlr
mutation 2, Bruce Beutler
MGI:6199990
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ebf1m2Btlr/Ebf1m2Btlr C57BL/6J-Ebf1m2Btlr MGI:6199992


Genotype
MGI:6199992
hm1
Allelic
Composition
Ebf1m2Btlr/Ebf1m2Btlr
Genetic
Background
C57BL/6J-Ebf1m2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ebf1m2Btlr mutation (0 available); any Ebf1 mutation (73 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• of B cells, IgM+ B cells, and IgD+ B cells in the peripheral blood
• reduced T-independent antibody response to NP-Ficoll
• reduced T-dependent antibody responses toalum-precipitated OVA
• reduced T-dependent antibody responses to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)

immune system
• of B cells, IgM+ B cells, and IgD+ B cells in the peripheral blood
• reduced T-dependent antibody responses toalum-precipitated OVA
• reduced T-dependent antibody responses to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)
• reduced T-independent antibody response to NP-Ficoll
• reduced T-independent antibody response to NP-Ficoll
• reduced T-dependent antibody responses toalum-precipitated OVA
• reduced T-dependent antibody responses to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)
• in response to TLR7 ligand, R848





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/02/2024
MGI 6.13
The Jackson Laboratory