Sall4^tm1Brd
Targeted Allele Detail

Summary

• Symbol: Sall4^tm1Brd
• Name: spalt like transcription factor 4; targeted mutation 1, Allan Bradley
• MGI ID: MGI:3698290
• Synonyms: Sall4^Brdm1, Sall4^m1
• Gene: Sall4 Location: Chr2:168590252-168609121 bp, - strand Genetic Position: Chr2, 88.99 cM
• Alliance: Sall4^tm1Brd page

Head, kidney, and anogenital tract defects in Sall4^tm1Brd/Sall4⁺ mice

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117866
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 2-4 were replaced with a floxed neo cassette. (J:117866)

Disease models

Expression

In Structures Affected by this Mutation:

12 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sall4 Mutation: 144 strains or lines available

References

• Original: J:117866 Warren M, et al., A Sall4 mutant mouse model useful for studying the role of Sall4 in early embryonic development and organogenesis. Genesis. 2007 Jan;45(1):51-8
• All: 1 reference(s)