Gt(ROSA)26Sortm1(DTA)Riet
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm1(DTA)Riet |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Dieter Riethmacher |
MGI ID: |
MGI:3055489 |
Synonyms: |
DTA, R26:lacZbpAfloxDTA, R26lacZbpAfloxDTA, R26:LacZ/DT-A, R26R-DTA, ROSA26-DTA, ROSA26-DT-A, ROSA-DTA |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm1(DTA)Riet page
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Germline Transmission: |
Earliest citation of germline transmission:
J:92789
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Parent Cell Line: |
E14.1 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Conditional ready, Inserted expressed sequence, Reporter) |
Mutation: |
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Insertion
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Mutation details: A targeting vector was designed to insert a splice acceptor sequence, a floxed lacZ, a diphtheria toxin fragment A (DTA) cassette, and a PGK-neo into intron 1. Staining demonstrated lacZ expression throughout embryogenesis and in every adult tissue examined.
(J:92789)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gt(ROSA)26Sor Mutation: |
942 strains or lines available
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Original: |
J:92789 Brockschnieder D, et al., Cell depletion due to diphtheria toxin fragment A after Cre-mediated recombination. Mol Cell Biol. 2004 Sep;24(17):7636-42 |
All: |
37 reference(s) |
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