Traj18^tm1.1Kro
Targeted Allele Detail

Summary

• Symbol: Traj18^tm1.1Kro
• Name: T cell receptor alpha joining 18; targeted mutation 1.1, Mitchell Kronenberg
• MGI ID: MGI:5788003
• Gene: Traj18 Location: Chr14:54438234-54438299 bp, + strand Genetic Position: Chr14, 27.69 cM
• Alliance: Traj18^tm1.1Kro page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:232957
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting vector contains a loxP site followed by an FRT-flanked neomycin cassette upstream of the J alpha 18 (J alpha 281) gene segment, a second loxP site was placed downstream. Cre-mediated recombination removed the J alpha 18 segment and neo cassette. (J:232957)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Traj18 Mutation: 4 strains or lines available

References

• Original: J:232957 Chandra S, et al., A new mouse strain for the analysis of invariant NKT cell function. Nat Immunol. 2015 Aug;16(8):799-800
• All: 6 reference(s)