Gt(ROSA)26Sortm1Fia
Targeted Allele Detail
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| Symbol: |
Gt(ROSA)26Sortm1Fia |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Fraz A Ismat |
| MGI ID: |
MGI:3689410 |
| Synonyms: |
HA-GRDk |
| Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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| Alliance: |
Gt(ROSA)26Sortm1Fia page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:114455
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: A vector containing a HA-tagged segment of human neurofibromatosis 1 cDNA encoding the 216 amino acid GTPase-activating protein-related domain was inserted into the locus with a floxed PGK-neo. The presence of the neo blocked expression of the mutant protein.
(J:114455)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Gt(ROSA)26Sor Mutation: |
1046 strains or lines available
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| Original: |
J:114455 Ismat FA, et al., The neurofibromin GAP-related domain rescues endothelial but not neural crest development in Nf1 mice. J Clin Invest. 2006 Sep;116(9):2378-84 |
| All: |
4 reference(s) |
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Analysis Tools
