Cd68^tm1Shnd
Targeted Allele Detail

Summary

• Symbol: Cd68^tm1Shnd
• Name: CD68 antigen; targeted mutation 1, Christian Schindler
• MGI ID: MGI:5285208
• Gene: Cd68 Location: Chr11:69555039-69556979 bp, - strand Genetic Position: Chr11, 42.86 cM
• Alliance: Cd68^tm1Shnd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:175275
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neo cassette was inserted downstream of the transcription initiation site. The absence of protein expression was confirmed by western blot analysis on peritoneal-elicited cell extracts. (J:175275)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd68 Mutation: 34 strains or lines available

References

• Original: J:175275 Song L, et al., Deletion of the murine scavenger receptor CD68. J Lipid Res. 2011 Aug;52(8):1542-50
• All: 2 reference(s)