Gt(ROSA)26Sor^{tm1(CAG-Bcl3,-EGFP)Hoev}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-Bcl3,-EGFP)Hoev}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Nadine Hovelmeyer
• MGI ID: MGI:5574111
• Synonyms: Bcl-3^Ind
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-Bcl3,-EGFP)Hoev} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208980
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(CAG-Bcl3,-EGFP)Hoev} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Bcl3 (MGI:88140)

• Mutation details: The targeting construct introduced into the locus a CAG promoter, floxed neomycin resistance/STOP cassette, Bcl3 coding sequence and FRT-flanked IRES-EGFP. (J:208980)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 942 strains or lines available

References

• Original: J:208980 Hovelmeyer N, et al., Overexpression of Bcl-3 inhibits the development of marginal zone B cells. Eur J Immunol. 2014 Feb;44(2):545-52
• All: 3 reference(s)