Stra6^tm1Jwu
Targeted Allele Detail

Summary

• Symbol: Stra6^tm1Jwu
• Name: stimulated by retinoic acid gene 6; targeted mutation 1, Jiangping Wu
• MGI ID: MGI:5587960
• Gene: Stra6 Location: Chr9:57971071-58061279 bp, + strand Genetic Position: Chr9, 31.63 cM, cytoband C
• Alliance: Stra6^tm1Jwu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:211118
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: A neomycin resistance cassette replaced exon 2. RT-PCR confirmed the absence of transcript expression in spleen cells. (J:211118)

Generation of the Stra6^tm1Jwu allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stra6 Mutation: 48 strains or lines available

References

• Original: J:211118 Terra R, et al., To investigate the necessity of STRA6 upregulation in T cells during T cell immune responses. PLoS One. 2013;8(12):e82808
• All: 1 reference(s)