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Znfx1em1Xua
Endonuclease-mediated Allele Detail
Summary
Symbol: Znfx1em1Xua
Name: zinc finger, NFX1-type containing 1; endonuclease-mediated mutation 1, Anlong Xu
MGI ID: MGI:8187911
Gene: Znfx1  Location: Chr2:166877713-166904926 bp, - strand  Genetic Position: Chr2, 87.22 cM
Alliance: Znfx1em1Xua page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
    CRISPR/cas9 mediated recombination using guide RNAs created a deletion spanning exons 3 through 11. (J:282875)
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Znfx1 Mutation:  106 strains or lines available
References
Original:  J:282875 Wang Y, et al., Mitochondria-localised ZNFX1 functions as a dsRNA sensor to initiate antiviral responses through MAVS. Nat Cell Biol. 2019 Nov;21(11):1346-1356
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory