Pdss2^tm1Dalg
Targeted Allele Detail

Summary

• Symbol: Pdss2^tm1Dalg
• Name: prenyl (solanesyl) diphosphate synthase, subunit 2; targeted mutation 1, David L Gasser
• MGI ID: MGI:3797368
• Synonyms: Pdss2^loxP
• Gene: Pdss2 Location: Chr10:43097482-43340878 bp, + strand Genetic Position: Chr10, 22.91 cM, cytoband B2
• Alliance: Pdss2^tm1Dalg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136670
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted upstream of exon 2 and an additional loxP site was inserted downstream of exon 2. Germ line, cre-mediated recombination was used to remove the neo cassette leaving exon 2 floxed. (J:136670)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdss2 Mutation: 31 strains or lines available

References

• Original: J:136670 Peng M, et al., Primary coenzyme Q deficiency in Pdss2 mutant mice causes isolated renal disease. PLoS Genet. 2008 Apr;4(4):e1000061
• All: 3 reference(s)