Snd1^tm1.2Elws
Targeted Allele Detail

Summary

• Symbol: Snd1^tm1.2Elws
• Name: staphylococcal nuclease and tudor domain containing 1; targeted mutation 1.2, Emma L Woods
• MGI ID: MGI:7286446
• Gene: Snd1 Location: Chr6:28480332-28935161 bp, + strand Genetic Position: Chr6, 11.99 cM
• Alliance: Snd1^tm1.2Elws page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:324590
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct introduced upstream of exon 3 a loxP site and downstream of exon 3 an FRT-flanked neomycin resistance cassette with a 3 prime loxP site. Flp-mediated recombination removed the selection cassette and left exon 2 floxed. Cre-mediated recombination removed exon 3. (J:324590)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Snd1 Mutation: 99 strains or lines available

References

• Original: J:324590 Wang X, et al., SND1 promotes Th1/17 immunity against chlamydial lung infection through enhancing dendritic cell function. PLoS Pathog. 2021 Feb;17(2):e1009295
• All: 1 reference(s)