Nfat5tm1.1Joar
Targeted Allele Detail
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Symbol: |
Nfat5tm1.1Joar |
Name: |
nuclear factor of activated T cells 5; targeted mutation 1.1, Jose Aramburu |
MGI ID: |
MGI:4840524 |
Synonyms: |
NFAT5Flox |
Gene: |
Nfat5 Location: Chr8:108020102-108106149 bp, + strand Genetic Position: Chr8, 53.93 cM, cytoband D2
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Alliance: |
Nfat5tm1.1Joar page
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Germline Transmission: |
Earliest citation of germline transmission:
J:148271
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Parent Cell Line: |
Bruce 4 (ES Cell)
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Strain of Origin: |
B6.Cg-Thy1a
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 6 and an FRT flanked neo cassette with a 3' loxP site was inserted downstream of exon 6. Flp mediated recombination removed the neo cassette leaving exon 6 floxed.
(J:148271)
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Generation of the floxed Nfat5tm1.1Joar allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Nfat5 Mutation: |
62 strains or lines available
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Original: |
J:148271 Drews-Elger K, et al., The transcription factor NFAT5 is required for cyclin expression and cell cycle progression in cells exposed to hypertonic stress. PLoS One. 2009;4(4):e5245 |
All: |
6 reference(s) |
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