Cxcl16^tm1Syon
Targeted Allele Detail

Summary

• Symbol: Cxcl16^tm1Syon
• Name: C-X-C motif chemokine ligand 16; targeted mutation 1, Shin Yonehara
• MGI ID: MGI:4414661
• Synonyms: SR-PSOX KO
• Gene: Cxcl16 Location: Chr11:70345215-70350810 bp, - strand Genetic Position: Chr11, 42.99 cM, cytoband B4
• Alliance: Cxcl16^tm1Syon page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:155199
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance gene replaced exons 1-3 via homologous recombination. Lack of RNA and protein expression were confirmed by real-time PCR and flow cytometry. (J:155199)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cxcl16 Mutation: 20 strains or lines available

References

• Original: J:155199 Shimaoka T, et al., Critical role for CXC chemokine ligand 16 (SR-PSOX) in Th1 response mediated by NKT cells. J Immunol. 2007 Dec 15;179(12):8172-9
• All: 8 reference(s)