Analysis Tools
immune system
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• in the liver
• but no decrease is seen in the thymus or spleen
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• the increase in serum levels of IFN gamma in null mice in response to alpha-galactosylceramide injection was only 20% of that seen in wild-type mice
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• the increase in serum levels of interleukin 4 in null mice in response to alpha-galactosylceramide injection was only 60% of that seen in wild-type mice.
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• liver leukocytes when stimulated with alpha-galactosylceramide for 72 hours produce less IFN gamma
• normal secretion when co-cultured with wild-type APC
• decreased production by CD4 T-cells after exposure to heat killed Propionibacterium acnes
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• liver leukocytes when stimulated with alpha-galactosylceramide for 72 hours produce less IL-4
• normal secretion when co-cultured with wild-type antigen-presenting cells
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• expression data indicates absence of liver damage in response to LPS administration in Propionibacterium acnes primed
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homeostasis/metabolism
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• the increase in serum levels of IFN gamma in null mice in response to alpha-galactosylceramide injection was only 20% of that seen in wild-type mice
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• the increase in serum levels of interleukin 4 in null mice in response to alpha-galactosylceramide injection was only 60% of that seen in wild-type mice.
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• decreased inhibition of B16 melanoma cell growth by alpha-galactosylceramide treatment
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neoplasm
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• decreased inhibition of B16 melanoma cell growth by alpha-galactosylceramide treatment
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hematopoietic system
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• in the liver
• but no decrease is seen in the thymus or spleen
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