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Tg(Tbx1-cre)1Joe
Transgene Detail
Summary
Symbol: Tg(Tbx1-cre)1Joe
Name: transgene insertion 1, Jonathan A Epstein
MGI ID: MGI:3037834
Synonyms: Tbx1-Cre, Tbx1-enCre
Transgene: Tg(Tbx1-cre)1Joe  Location: unknown  
Alliance: Tg(Tbx1-cre)1Joe page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Tbx1-cre)1Joe expression driven by 1 gene
 
Mutation detailsSequence encoding cre recombinase was adjoined to mouse Tbx1 promoter sequence that extended 16 kb from the start codon and included the proximal promoter and three conserved enhancer regions. The expression pattern of cre recombinase recapitulated that of Tbx1, with expression observed in the mesenchyme, otic vesicle, and somites during development. (J:88814)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tbx1 (mouse)
Summary of all recombinase alleles driven by Tbx1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:88814 Brown CB, et al., Cre-mediated excision of Fgf8 in the Tbx1 expression domain reveals a critical role for Fgf8 in cardiovascular development in the mouse. Dev Biol. 2004 Mar 1;267(1):190-202
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory