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Targeted Allele Detail
Symbol: Snai2tm2Grid
Name: snail family zinc finger 2; targeted mutation 2, Tom Gridley
MGI ID: MGI:2447176
Synonyms: Slug-, Slughdelta1, Snai2del1
Gene: Snai2  Location: Chr16:14523716-14527249 bp, + strand  Genetic Position: Chr16, 10.07 cM
Alliance: Snai2tm2Grid page
Germline Transmission:  Earliest citation of germline transmission: J:48521
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe gene was inactivated by replacement of the entire protein coding region with a PGK-neo cassette via homologous recombination. (J:48521)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
In Mice Carrying this Mutation: 15 assay results
In Structures Affected by this Mutation: 12 anatomical structures
Tumor Data
List all tumor models in MMHCdb carrying Snai2tm2Grid
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Snai2 Mutation:  22 strains or lines available
Original:  J:48521 Jiang R, et al., The Slug gene is not essential for mesoderm or neural crest development in mice. Dev Biol. 1998 Jun 15;198(2):277-85
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory