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All mouse models of hematologic cancer with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | acute myeloid leukemia | \Cebpatm8.1Nerl/\Cebpatm8.1Nerl | involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 | J:136134 | View | |||
| acute myeloid leukemia | \Crebbptm1Dli/\Crebbp+ | involves: 129S6/SvEvTac * C57BL/6 | J:60630 | View | ||||
| acute myeloid leukemia | \Flt3tm1.1Dosm/\Flt3+ | B6.129(C)-Flt3tm1.1Dosm | J:205200 | View | ||||
| acute myeloid leukemia |
\Flt3tm1Dgg/\Flt3+ \Kmt2atm1Clgr/\Kmt2a+ |
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6J | J:189096 | View | ||||
| acute myeloid leukemia |
\Flt3tm1Dgg/\Flt3tm1Dgg \Kmt2atm1Clgr/\Kmt2a+ |
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6J | J:189096 | View | ||||
| acute myeloid leukemia | \Flt3tm2.1Dosm/\Flt3+ | B6.129(C)-Flt3tm2.1Dosm | J:205200 | View | ||||
| acute myeloid leukemia |
\Kmt2atm1Saam/\Kmt2a+ \Tg(Mx1-cre)1Cgn/0 |
involves: 129S1/Sv * C57BL/6 * CBA | J:140628 | View | ||||
| acute myeloid leukemia | \Kmt2atm2(MLLT3)Thr/\Kmt2a+ | involves: 129P2/OlaHsd | J:56340 | View | ||||
| acute myeloid leukemia | \Tg(Vav1-Asxl1*Y588X)#Fcy/0 | C57BL/6-Tg(Vav1-Asxl1*Y588X)#Fcy | J:257690 | View | ||||
| B-cell lymphoma |
\Ezh2tm1.1Nesh/\Ezh2+ \Cd19tm1(cre)Cgn/\Cd19+ |
involves: 129 * 129P2/OlaHsd * C57BL/6 | J:239472 | View | ||||
| Burkitt lymphoma | \Ightm1(Myc)Janz/\Igh+ | involves: 129X1/SvJ * C57BL/6 | J:96785 | View | ||||
| Burkitt lymphoma | \Myctm1Lbox/\Myc+ | involves: 129S1/Sv * 129X1/SvJ * FVB/N | J:97900 | View | ||||
| Burkitt lymphoma | \Myctm1Lbox/\Myctm1Lbox | involves: 129S1/Sv * 129X1/SvJ * FVB/N | J:97900 | View | ||||
| Burkitt lymphoma | \Tg(IghMyc)22Bri/0 | involves: C57BL/6 * SJL | J:78177, J:186117 | View | ||||
| essential thrombocythemia | \DccTg(H2-Kb-Jak2*V617F)1Shmd/\Dcc+ | involves: C57BL/6 * DBA/2 | J:130189 | View | ||||
| essential thrombocythemia |
\Jak2tm1(JAK2)Argr/\Jak2+ \Tg(Mx1-cre)1Cgn/0 |
involves: 129S7/SvEvBrd * C57BL/6 * CBA | J:164539 | View | ||||
| juvenile myelomonocytic leukemia |
\Nf1tm1Fcr/\Nf1+ \Ptentm1Hwu/\Ptentm1Hwu \Tg(Mx1-cre)1Cgn/0 |
B6.Cg-Tg(Mx1-cre)1Cgn Nf1tm1Fcr Ptentm1Hwu | J:232645 | View | ||||
| juvenile myelomonocytic leukemia |
\Nf1tm1Par/\Nf1tm1Par \Tg(Mx1-cre)1Cgn/0 |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA | J:90973 | View | ||||
| juvenile myelomonocytic leukemia |
\Ptpn11tm6Bgn/\Ptpn11+ \Tg(Mx1-cre)1Cgn/0 |
involves: 129S6/SvEvTac * C57BL/6 * CBA | J:148430 | View | ||||
| myelodysplastic syndrome |
\Asxl1tm1.1Iaai/\Asxl1tm1.1Iaai \Tg(Mx1-cre)1Cgn/0 |
involves: 129S/SvEv * C57BL/6 * CBA | J:208092 | View | ||||
| myelodysplastic syndrome |
\Asxl1tm1.1Iaai/\Asxl1tm1.1Iaai \Tg(VAV1-cre)1Graf/0 |
involves: 129S/SvEv * C57BL/6 | J:208092 | View | ||||
| myelodysplastic syndrome | \Asxl1tm1.1Mjxu/\Asxl1+ | involves: 129 * C57BL/6 | J:208085 | View | ||||
| myelodysplastic syndrome | \Asxl1tm1.1Mjxu/\Asxl1tm1.1Mjxu | involves: 129 * C57BL/6 | J:208085 | View | ||||
| myelodysplastic syndrome |
\Sf3b1tm1.1Mdf/\Sf3b1+ \Tet2tm1.1Iaai/\Tet2tm1.1Iaai \Tg(Mx1-cre)1Cgn/? |
involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA/J | J:234976 | View | ||||
| myelodysplastic syndrome | \Sf3b1tm1Hko/\Sf3b1+ | Not Specified | J:324276 | View | ||||
| myelodysplastic syndrome |
\Srsf2tm1.1Oaw/\Srsf2+ \Tg(Mx1-cre)1Cgn/? |
B6.Cg-Tg(Mx1-cre)1Cgn Srsf2tm1.1Oaw | J:221404 | View | ||||
| myelodysplastic syndrome | \Tg(Vav1-Asxl1*Y588X)#Fcy/0 | C57BL/6-Tg(Vav1-Asxl1*Y588X)#Fcy | J:257690 | View | ||||
| myelofibrosis | \Jak2tm1.1Jlvl/\Jak2tm1.1Jlvl | involves: 129S2/SvPas * C57BL/6 | J:163497 | View | ||||
| myelofibrosis | \Tg(H2-Kb-Jak2*V617F)2Shmd/0 | involves: C57BL/6 * DBA/2 | J:130189 | View | ||||
| myeloproliferative neoplasm | \Pdgfrbb2b2903Clo/\Pdgfrbb2b2903Clo | C57BL/6J-Pdgfrbb2b2903Clo | J:175213 | View | ||||
| polycythemia vera | \DccTg(H2-Kb-Jak2*V617F)1Shmd/\Dcc+ | involves: C57BL/6 * DBA/2 | J:130189 | View | ||||
| polycythemia vera | \Jak2tm1.1Jlvl/\Jak2tm1.1Jlvl | involves: 129S2/SvPas * C57BL/6 | J:163497 | View | ||||
| polycythemia vera | \Jak2tm1.2Ble/\Jak2+ | involves: 129S6/SvEvTac * C57BL/6 * FVB/N | J:160883 | View | ||||
| polycythemia vera |
\Jak2tm1.2Ble/\Jak2+ \Picalmtm1.1Tmae/\Picalm+ \Commd10Tg(Vav1-icre)A2Kio/\Commd10+ |
involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * CBA * SJL | J:220728 | View | ||||
| polycythemia vera |
\Jak2tm1Mohi/\Jak2+ \Tg(Mx1-cre)1Cgn/0 |
involves: C57BL/6 * CBA | J:183821 | View | ||||
| polycythemia vera |
\Jak2tm1Mohi/\Jak2tm1Mohi \Tg(Mx1-cre)1Cgn/0 |
involves: C57BL/6 * CBA | J:183821 | View | ||||
| | acute lymphoblastic leukemia |
\Ezh2tm2Sho/\Ezh2tm2.1Sho \Tg(Mx1-cre)1Cgn/0 |
involves: 129S1/Sv * C57BL/6 * CBA | J:182211 | View | |||
| acute lymphoblastic leukemia |
\Ezh2tm2Sho/\Ezh2tm2Sho \Tg(Mx1-cre)1Cgn/0 |
involves: 129S1/Sv * C57BL/6 * CBA | J:182211 | View | ||||
| acute lymphoblastic leukemia |
\Kmt2atm1Saam/\Kmt2a+ \Tg(Mx1-cre)1Cgn/0 |
involves: 129S1/Sv * C57BL/6 * CBA | J:140628 | View | ||||
| acute lymphoblastic leukemia |
\Ptentm1Hwu/\Ptentm1Hwu \Tg(Mx1-cre)1Cgn/0 |
involves: 129S4/SvJae * C57BL/6 * CBA | J:169097 | View | ||||
| acute lymphoblastic leukemia | \Tg(CD2-Lmo2)#Thr/0 | involves: C57BL/6 * CBA | J:102058 | View | ||||
| acute lymphoblastic leukemia | \Tg(Lck-Notch3)#Issc/0 | involves: C57BL/6 * DBA/2 | J:63300 | View | ||||
| acute myeloid leukemia | \Arid4atm1Alb/\Arid4atm1Alb | involves: 129S7/SvEvBrd | J:141004 | View | ||||
| acute myeloid leukemia |
\Arid4atm1Alb/\Arid4atm1Alb \Arid4btm1Alb/\Arid4b+ |
involves: 129S7/SvEvBrd | J:141004 | View | ||||
| acute myeloid leukemia |
\Mybl2tm1.1Jof/\Mybl2+ \Tg(Zp3-cre)3Mrt/0 |
involves: 129S2/SvPas * C57BL/6 * FVB/N | J:196804 | View | ||||
| acute myeloid leukemia | \Spi1tm1.3Dgt/\Spi1tm1.3Dgt | involves: 129 * BALB/c * C57BL/6 | J:90331 | View | ||||
| chronic myeloid leukemia | \Chordc1tm1Mbra/\Chordc1+ | involves: 129 * C57BL/6 | J:222040 | View | ||||
| chronic myeloid leukemia |
\Ncstntm1.1Akli/\Ncstntm1.1Akli \Tg(Mx1-cre)1Cgn/0 |
involves: 129 * C57BL/6 * CBA * SJL | J:172442 | View | ||||
| chronic myeloid leukemia |
\Ncstntm1.1Akli/\Ncstntm1.1Akli \Tg(VAV1-cre)1Graf/0 |
involves: 129 * C57BL/6 * SJL | J:172442 | View | ||||
| chronic myeloid leukemia | \Sh2b3tm1Paw/\Sh2b3tm1Paw | involves: 129S1/Sv * 129X1/SvJ | J:161643 | View | ||||
| chronic myeloid leukemia | \Sipa1tm1Nm/\Sipa1+ | involves: 129P2/OlaHsd * C57BL/6 | J:97239 | View | ||||
| chronic myeloid leukemia | \Sipa1tm1Nm/\Sipa1tm1Nm | involves: 129P2/OlaHsd * C57BL/6 | J:97239 | View | ||||
| chronic myelomonocytic leukemia |
\Kdm6atm1Cdcn/\Kdm6atm1Cdcn \Tg(CAG-cre/Esr1*)5Amc/0 |
involves: C57BL/6J * CBA | J:263565 | View | ||||
| chronic myelomonocytic leukemia |
\Kdm6atm1Cdcn/Y \Tg(CAG-cre/Esr1*)5Amc/0 |
involves: C57BL/6J * CBA | J:263565 | View | ||||
| diffuse large B-cell lymphoma | \Smurf2Gt(RRA098)Byg/\Smurf2Gt(RRA098)Byg | involves: 129P2/OlaHsd * C57BL/6 | J:245679 | View | ||||
| diffuse large B-cell lymphoma | \Trp53tm1.2Awbr/\Trp53tm1.2Awbr | involves: C57BL/6 | J:173271 | View | ||||
| diffuse large B-cell lymphoma |
\Trp53tm1Tyj/\Trp53tm1Tyj \Tg(Ly6e-MALT1)#Isg/0 |
involves: 129S2/SvPas * C57BL/6 * CBA | J:185590 | View | ||||
| essential thrombocythemia | \Mybboo/\Mybboo | involves: C57BL/6 | J:167270 | View | ||||
| familial chronic myelocytic leukemia-like syndrome |
\Irf8myls/\Irf8myls \Slc11a1r/\Slc11a1r |
BXH2/TyJ | J:97931 | View | ||||
| familial chronic myelocytic leukemia-like syndrome |
\Irf8myls/\Irf8myls \Slc11a1r/\Slc11a1r |
involves: A/J * BXH2/TyJ | J:97931 | View | ||||
| familial chronic myelocytic leukemia-like syndrome | \Irf8tm1Hor/\Irf8+ | either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6) | J:36038 | View | ||||
| familial chronic myelocytic leukemia-like syndrome | \Irf8tm1Hor/\Irf8tm1Hor | either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6) | J:36038 | View | ||||
| follicular lymphoma | \Rarres1tm1.2Mhl/\Rarres1+ | involves: 129S1/SvImJ * C57BL/6 * FVB/N * NIH Black Swiss | J:324270 | View | ||||
| follicular lymphoma | \Rarres1tm1.2Mhl/\Rarres1tm1.2Mhl | involves: 129S1/SvImJ * C57BL/6 * FVB/N * NIH Black Swiss | J:324270 | View | ||||
| follicular lymphoma | \Rarres1tm1d(KOMP)Wtsi/\Rarres1+ | involves: C57BL/6N | J:324270 | View | ||||
| juvenile myelomonocytic leukemia | \Flt3tm1Dgg/\Flt3+ | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:126003 | View | ||||
| juvenile myelomonocytic leukemia | \Flt3tm1Dgg/\Flt3tm1Dgg | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:126003 | View | ||||
| juvenile myelomonocytic leukemia |
\Krastm4Tyj/\Kras+ \Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/\Gt(ROSA)26Sor+ \Tg(Flt3-cre)#Ccb/0 |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 | J:247853 | View | ||||
| juvenile myelomonocytic leukemia |
\Krastm4Tyj/\Kras+ \Tg(Mx1-cre)1Cgn/0 |
involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA | J:88163 | View | ||||
| juvenile myelomonocytic leukemia |
\Krastm4Tyj/\Kras+ \Tg(Mx1-cre)1Cgn/0 |
involves: 129S4/SvJae * C57BL/6 * CBA | J:87429, J:115071 | View | ||||
| lymphoid leukemia | \Tg(Lck-Tal1)4709Led/0 | FVB/N-Tg(Lck-Tal1)4709Led | J:36076 | View | ||||
| lymphoma |
\Gt(ROSA)26Sortm1(tTA,tetO-Mir155)Fjsl/\Gt(ROSA)26Sor+ \Tg(Nes-cre)1Wmz/0 |
involves: 129 * C57BL/6 * FVB/N * SJL/J | J:185598 | View | ||||
| lymphoma | \Tg(H2-K-Hmga1)#Lmsr/0 | involves: C57BL/6 * SJL | J:90252 | View | ||||
| multiple myeloma | \Tg(Igh-Maf)68Staka/0 | C57BL/6-Tg(Igh-Maf)68Staka | J:168074 | View | ||||
| multiple myeloma | \Tg(Igh-Maf)524Staka/0 | involves: C57BL/6 * C57BL/6J * DBA/2 | J:168074 | View | ||||
| myelodysplastic syndrome |
\Atg7tm1Tchi/\Atg7tm1Tchi \Commd10Tg(Vav1-icre)A2Kio/\Commd10+ |
involves: C57BL/6NCrlj * C57BL/10 * CBA/Ca * CBA/JNCrlj | J:176843 | View | ||||
| myelodysplastic syndrome |
\Bap1tm1.1Geno/\Bap1tm1.1Geno \Gt(ROSA)26Sortm9(cre/ESR1)Arte/\Gt(ROSA)26Sor+ |
involves: C57BL/6 * C57BL/6NTac | J:187380 | View | ||||
| myelodysplastic syndrome | \Crebbptm1Dli/\Crebbp+ | involves: 129S6/SvEvTac * C57BL/6 | J:191503 | View | ||||
| myelodysplastic syndrome | \Egr1tm1Jmi/\Egr1tm1Jmi | involves: 129 * C57BL/6 | J:123870 | View | ||||
| myelodysplastic syndrome | \Gata1tm1Mym/\Gata1+ | involves: 129P2/OlaHsd | J:88685 | View | ||||
| myelodysplastic syndrome | \Macroh2a1tm1.1Oxbo/\Macroh2a1tm1.1Oxbo | B6.Cg-Macroh2a1tm1.1Oxbo | J:293382 | View | ||||
| myelodysplastic syndrome |
\Mybl2tm1.1Jof/\Mybl2+ \Tg(Zp3-cre)3Mrt/0 |
involves: 129S2/SvPas * C57BL/6 * FVB/N | J:196804 | View | ||||
| myelodysplastic syndrome | \Npm1tm1Ppp/\Npm1+ | involves: 129S1/Sv * C57BL/6 | J:101494 | View | ||||
| myelodysplastic syndrome | \Polgtm1Prol/\Polgtm1Prol | B6J.129S7-Polgtm1Prol | J:154187 | View | ||||
| myelodysplastic syndrome | \Samd9ltm1Homy/\Samd9l+ | involves: 129P2/OlaHsd | J:202604 | View | ||||
| myelodysplastic/myeloproliferative neoplasm | \Dido1tm1Cmar/\Dido1tm1Cmar | involves: 129S1/Sv * 129X1/SvJ | J:101201 | View | ||||
| myelofibrosis | \Gata1tm2Sho/\Gata1tm2Sho | involves: 129S4/SvJae * C57BL/6 * CD-1 | J:78348 | View | ||||
| myelofibrosis | \Gata1tm2Sho/Y | involves: 129S4/SvJae * C57BL/6 * CD-1 | J:78348 | View | ||||
| myelofibrosis | \Mybboo/\Mybboo | involves: C57BL/6 | J:167270 | View | ||||
| myelofibrosis | \Ncor2tm1Rev/\Ncor2tm1Rev | involves: 129/Sv * C57BL/6 | J:202976 | View | ||||
| myeloproliferative neoplasm |
\Jak2tm1.1Ble/\Jak2+ \Commd10Tg(Vav1-icre)A2Kio/\Commd10+ |
involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca | J:257910 | View | ||||
| myeloproliferative neoplasm | \Tg(Vav1-Asxl1*Y588X)#Fcy/0 | C57BL/6-Tg(Vav1-Asxl1*Y588X)#Fcy | J:257690 | View | ||||
| non-Hodgkin lymphoma | \Mtss1Gt(CSC156)Byg/\Mtss1Gt(CSC156)Byg | B6.129P2-Mtss1Gt(CSC156)Byg | J:186118 | View | ||||
| non-Hodgkin lymphoma | \S1pr2tm1Ajml/\S1pr2tm1Ajml | 129S5/SvEvBrd-S1pr2tm1Ajml | J:154439 | View | ||||
| non-Hodgkin lymphoma | \S1pr2tm1Ajml/\S1pr2tm1Ajml | involves: 129S5/SvEvBrd * C57BL/6 | J:154439 | View | ||||
| peripheral T-cell lymphoma | \Rc3h1san/\Rc3h1+ | involves: C57BL/6JSfdAnu | J:189087 | View | ||||
| T-cell acute lymphoblastic leukemia |
\Nbnem7Jpt/\Nbntm2Zqw \Tg(VAV1-cre)1Graf/0 |
involves: 129P2/OlaHsd | J:277750 | View | ||||
| T-cell acute lymphoblastic leukemia | \Tg(H2-K-Hmga1)#Lmsr/0 | involves: C57BL/6 * SJL | J:90252 | View | ||||
| T-cell adult acute lymphocytic leukemia |
\Gt(ROSA)26Sortm18(Zeb2)Jhai/\Gt(ROSA)26Sortm18(Zeb2)Jhai \Tg(Cd4-cre)1Cwi/0 |
involves: C57BL/6 * CD-1 * DBA/2 | J:263520 | View | ||||
| T-cell adult acute lymphocytic leukemia |
\Gt(ROSA)26Sortm18(Zeb2)Jhai/\Gt(ROSA)26Sortm18(Zeb2)Jhai \Tg(Tek-cre)1Ywa/0 |
involves: C57BL/6 * CD-1 * SJL | J:263520 | View | ||||
| T-cell adult acute lymphocytic leukemia | \Tg(Lck-Tax)53Hall/0 | involves: C57BL/6 | J:129531, J:214623 | View | ||||
| | acute lymphoblastic leukemia |
\Ikzf1tm1Kast/\Ikzf1+ \Tg(BCR/ABL)623Hkp/0 |
involves: 129S2/SvPas * C57BL/6 * CBA | J:160846 | View | |||
| acute promyelocytic leukemia |
\Pmltm1.1Ews/\Pmltm1.1Ews \Tg(PML-RARA)556Kog/0 |
FVB.Cg-Pmltm1.1Ews Tg(PML-RARA)556Kog | J:262172 | View | ||||
| acute promyelocytic leukemia |
\Tg(CTSG-ZBTB16/RARA)#Ppp/0 \Zbtb16tm1Ppp/\Zbtb16tm1Ppp |
involves: 129S1/Sv | J:65878 | View | ||||
| transient myeloproliferative syndrome |
\Gata1tm1Mym/\Gata1tm1Mym \Tg(Gata1*)#Mym/0 |
involves: 129P2/OlaHsd * C57BL/6 * DBA/2J | J:158252 | View | ||||
| transient myeloproliferative syndrome |
\Gata1tm1Mym/Y \Tg(Gata1*)#Mym/0 |
involves: 129P2/OlaHsd * C57BL/6 * DBA/2J | J:158252 | View | ||||
| Transgenes and Other Mutations | acute leukemia | \Tg(Ly6a-SET/NUP214)2969Gcg/0 | involves: FVB/NJ | J:142938 | View | |||
| acute lymphoblastic leukemia | \Tg(Igh-HMGA2)#Cro/0 | FVB/N-Tg(Igh-HMGA2)#Cro | J:233225 | View | ||||
| acute myeloid leukemia | \Tg(CMV-SALL4_iB)#Chai/? | Not Specified | J:115037 | View | ||||
| acute myeloid leukemia | \Tg(Vav1-ERG)#Jpim/0 | involves: C57BL/6 | J:203438 | View | ||||
| acute promyelocytic leukemia | \Tg(CTSG-NUMA1/RARA)#Skr/0 | involves: C57BL/6 | J:88103 | View | ||||
| acute promyelocytic leukemia | \Tg(PML-RARA)556Kog/? | involves: FVB/N | J:39327 | View | ||||
| Burkitt lymphoma | \Tg(IGL-MYC)3Hm/0 | C57BL/6N-Tg(IGL-MYC)3Hm/Nci | J:65245 | View | ||||
| chronic lymphocytic leukemia | \Del(14Trim13-Dleu2)4Rdf/\Del(14Trim13-Dleu2)4Rdf | involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:156946 | View | ||||
| chronic lymphocytic leukemia |
\Del(14Trim13-Rnaseh2b)6Rdf/\+ \Cd19tm1(cre)Cgn/\Cd19+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:179879 | View | ||||
| chronic lymphocytic leukemia |
\Is(14)1Rdf \Is(14)2Rdf/\Del(14Trim13-Dleu2)4Rdf \Cd19tm1(cre)Cgn/\Cd19+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:156946 | View | ||||
| chronic lymphocytic leukemia |
\Is(14)1Rdf \Is(14)5Rdf/\Del(14Trim13-Rnaseh2b)6Rdf \Cd19tm1(cre)Cgn/\Cd19+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:179879 | View | ||||
| chronic lymphocytic leukemia |
\Mirc30em1Hhzg/\Mirc30em1Hhzg \Tg(Vav1-cre)#Cgp/0 |
involves: 129S4/SvJae * C57BL/6 * C57BL/6NRj | J:320883 | View | ||||
| chronic lymphocytic leukemia | \Mirc30tm1.2Rdf/\Mirc30tm1.2Rdf | involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:156946 | View | ||||
| chronic lymphocytic leukemia | \Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0 | FVB/N-Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro | J:162077 | View | ||||
| chronic lymphocytic leukemia |
\Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0 \Tg(Igh-V186.2-TCL1A)3Cro/0 |
involves: C3H * C57BL/6 * FVB/N | J:162077 | View | ||||
| chronic lymphocytic leukemia | \Tg(Igh-ROR1)1Kip/0 | C57BL/6-Tg(Igh-ROR1)1Kip | J:206368 | View | ||||
| chronic lymphocytic leukemia |
\Tg(Igh-ROR1)1Kip/0 \Tg(Igh-V186.2-TCL1A)3Cro/0 |
B6.Cg-Tg(Igh-ROR1)1Kip Tg(Igh-V186.2-TCL1A)3Cro | J:206368 | View | ||||
| chronic lymphocytic leukemia | \Tg(Igh-TCL1A)1Ypek/0 | FVB/N-Tg(Igh-TCL1A)1Ypek | J:160184 | View | ||||
| chronic lymphocytic leukemia | \Tg(Igh-V186.2-TCL1A)3Cro/0 | B6.Cg-Tg(Igh-V186.2-TCL1A)3Cro | J:206368 | View | ||||
| chronic lymphocytic leukemia | \Tg(Igh-V186.2-TCL1A)3Cro/0 | involves: C3H * C57BL/6 | J:76574 | View | ||||
| chronic lymphocytic leukemia | \Tg(Lck-TNFSF13)3919Mhah/0 | B6.Cg-Tg(Lck-TNFSF13)3919Mhah | J:94628 | View | ||||
| chronic myeloid leukemia |
\Gt(ROSA)26Sortm4(CAG-hsb5)Nki/\Gt(ROSA)26Sor+ \Tg(Mx1-cre)1Cgn/0 \Tg(Tal1-tTA)19Dgt/0 \Tg(tetO-BCR/ABL1)2Dgt/0 \TgTn(pb-sb-GrOnc)#aGsva/0 |
involves: 129P2/OlaHsd * C57BL/6 * CBA/J * DBA/2 * FVB/N | J:227558 | View | ||||
| chronic myeloid leukemia | \Tg(Ly6a-BCR/ABL1)IS1AIsg/0 | involves: C57BL/6J * CBA | J:144382 | View | ||||
| chronic myeloid leukemia | \Tg(Ly6a-BCR/ABL1)IS1BIsg/0 | involves: C57BL/6J * CBA | J:144382 | View | ||||
| chronic myeloid leukemia | \Tg(Ly6a-TK,-BCR/ABL1)IS9AIsg/0 | involves: C57BL/6J * CBA | J:144382 | View | ||||
| chronic myeloid leukemia |
\Tg(tetO-BCR/ABL1)2Dgt/0 \Tg(Tal1-tTA)19Dgt/0 |
involves: C57BL/6 * DBA/2 * FVB/N | J:96511 | View | ||||
| essential thrombocythemia |
\Tg(JAK2*V617F)FF1Rsko/0 \Commd10Tg(Vav1-icre)A2Kio/\Commd10+ |
involves: C57BL/6 * C57BL/10 * CBA/Ca | J:134364 | View | ||||
| essential thrombocythemia | \Tg(Vav1-JAK2*V617F)AZjz/0 | involves: C57BL/6 * DBA/2 | J:135993 | View | ||||
| extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue | \Tg(Ly6e-MALT1)#Isg/0 | involves: C57BL/6 * CBA | J:185590 | View | ||||
| follicular lymphoma | \Tg(Vav-BCL2)69Jad/0 | involves: C57BL/6J | J:88565 | View | ||||
| leukemia | \Tg(Vav1-STAT5B*N642H)726Biat/0 | C57BL/6NCrl-Tg(Vav1-STAT5B*N642H)726Biat | J:257519 | View | ||||
| lymphoma | \Tg(Vav1-STAT5B*N642H)726Biat/0 | C57BL/6NCrl-Tg(Vav1-STAT5B*N642H)726Biat | J:257519 | View | ||||
| multiple myeloma | \Tg(Cd4-NPM/ALK)N1Ingh/0 | either: (involves: BALB/c * Swiss Webster) or (involves: C57BL/6 * Swiss Webster) | J:82127 | View | ||||
| multiple myeloma | \Tg(Igkv3-5*-MYC)24Plbe/0 | C57BL/6J-Tg(Igkv3-5*-MYC)DLoxP4Plbe/PlbeMmmh | J:131912 | View | ||||
| myelodysplastic syndrome | \Tg(CMV-SALL4_iB)#Chai/? | Not Specified | J:115037 | View | ||||
| myelodysplastic syndrome | \Tg(Vav1-NUP98/HOXD13)C1Apla/0 | FVB/N-Tg(Vav1-NUP98/HOXD13)C1Apla | J:107446 | View | ||||
| myelodysplastic syndrome | \Tg(Vav1-NUP98/HOXD13)G2Apla/0 | C57BL/6-Tg(Vav1-NUP98/HOXD13)G2Apla | J:107446 | View | ||||
| myelofibrosis | \Tg(Vav1-JAK2*V617F)AZjz/0 | involves: C57BL/6 * DBA/2 | J:135993 | View | ||||
| non-Hodgkin lymphoma | \Tg(EmuSR-HDAC9)1468Kpet/0 | involves: C57BL/6 * CBA | J:237420 | View | ||||
| non-Hodgkin lymphoma |
\Tg(EmuSR-tTa)83Bop/\Tg(EmuSR-tTa)83Bop \Tg(tetO-NPM1/ALK,-luc)2Gde/0 |
involves: FVB/N | J:160236 | View | ||||
| non-Hodgkin lymphoma |
\Tg(EmuSR-tTa)83Bop/\Tg(EmuSR-tTa)83Bop \Tg(tetO-TPM3/ALK,-luc)2Gde/0 |
involves: FVB/N | J:160236 | View | ||||
| plasmacytoma | \Tg(H2-L-IL6)46Kish/\Tg(H2-L-IL6)46Kish | C.B6-Tg(H2-L-IL6)46Kish | J:74377 | View | ||||
| polycythemia vera |
\Tg(JAK2*V617F)FF1Rsko/0 \Tg(Mx1-cre)1Cgn/0 |
involves: C57BL/6 * CBA | J:134364 | View | ||||
| polycythemia vera | \Tg(Vav1-JAK2*V617F)AZjz/0 | involves: C57BL/6 * DBA/2 | J:135993 | View | ||||
| Additional Complex Models | acute leukemia |
\Cd3etm1Mal/\Cd3etm1Mal \Tg(Tcrb-TCF3/PBX1)23Gusa/0 |
involves: C3H * C57BL/6 * C57BL/6J | J:95693 | View | |||
| acute lymphoblastic leukemia |
\Etv6tm1.1(RUNX1,hsb5)Lvdw/\Etv6+ \TgTn(sb-T2/Onc)76Dla/0 |
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/N | J:174866 | View | ||||
| acute lymphoblastic leukemia |
\Tcf3tm1(PBX1)Mlc/\Tcf3+ \Cd19tm1(cre)Cgn/\Cd19+ |
involves: 129P2/OlaHsd * C57BL/6 | J:226241 | View | ||||
| acute lymphoblastic leukemia |
\Tcf3tm1(PBX1)Mlc/\Tcf3+ \Cd79atm1(cre)Reth/\Cd79a+ |
involves: BALB/c * C57BL/6 | J:226241 | View | ||||
| acute lymphoblastic leukemia |
\Tcf3tm1(PBX1)Mlc/\Tcf3+ \Tg(Mx1-cre)1Cgn/0 |
involves: C57BL/6 * C57BL/6J * CBA/J | J:226241 | View | ||||
| acute lymphoblastic leukemia |
\Tg(Lck-LMO1)11Sjk/0 \Tg(STIL-TAL1)A5.3Alpa/0 |
involves: C3H * C3H/HeRos * C57BL/6 * C57BL/10Ros | J:40868 | View | ||||
| acute lymphoblastic leukemia |
\Zfp36l1tm1.1Tnr/\Zfp36l1tm1.1Tnr \Zfp36l2tm1.1Tnr/\Zfp36l2tm1.1Tnr \Tg(CD2-icre)4Kio/0 |
involves: C57BL/6 * C57BL/10 * CBA/Ca * SJL | J:162388 | View | ||||
| acute myeloid leukemia | \Ctsgtm2.1(PML/RARA)Ley/\Ctsg+ | involves: 129X1/SvJ * C57BL/6 | J:84230, J:86458 | View | ||||
| acute myeloid leukemia |
\Nr4a1tm1Jmi/\Nr4a1tm1Jmi \Nr4a3tm1Omc/\Nr4a3tm1Omc |
involves: 129S/SvEv * 129S2/SvPas * C57BL/6 | J:121903 | View | ||||
| acute promyelocytic leukemia |
\Tg(CTSG-RARA/ZBTB16)#Ppp/0 \Tg(CTSG-ZBTB16/RARA)#Ppp/0 |
Not Specified | J:65878 | View | ||||
| acute promyelocytic leukemia |
\Tg(CTSG-RARA/ZBTB16)#Sjch/0 \Tg(CTSG-ZBTB16/RARA)#Sjch/0 |
Not Specified | J:194312 | View | ||||
| B-cell lymphoma |
\Cd19tm1(cre)Cgn/\Cd19+ \Inpp5dtm1Rav/\Inpp5dtm1Rav \Ptentm1Hwu/\Ptentm1Hwu |
involves: 129P2/OlaHsd * 129S4/SvJae | J:166155 | View | ||||
| chronic lymphocytic leukemia | \Ightm1.1(Tag)Rwhe/\Igh+ | involves: 129P2/OlaHsd * C57BL/6 | J:150315 | View | ||||
| chronic lymphocytic leukemia | \Ightm2.1(Tag)Rwhe/\Igh+ | involves: 129P2/OlaHsd * C57BL/6 | J:150315 | View | ||||
| chronic lymphocytic leukemia |
\Ighatm1(Myc)Janz/\Igha+ \Tg(Tnfsf13b)1Fma/0 |
involves: 129S1/Sv * C57BL/6 * DBA/2J | J:166158 | View | ||||
| chronic lymphocytic leukemia |
\Is(14)1Rdf/\Is(14)1Rdf \Is(14)5Rdf/\Is(14)5Rdf \Cd19tm1(cre)Cgn/\Cd19+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:179879 | View | ||||
| chronic lymphocytic leukemia |
\Tg(BCL2/IGH)#Jcre/0 \Tg(H2-K/Igh-Traf2*)#Ywc/0 |
involves: BALB/c * C57BL/6 * CBA/J * FVB/N * SJL/J * SWR/J | J:94116 | View | ||||
| chronic myeloid leukemia |
\Dok1tm1Ppp/\Dok1+ \Tg(Tec-BCR/ABL1)5Hhi/0 |
involves: 129S1/Sv | J:95334 | View | ||||
| chronic myeloid leukemia |
\Dok1tm1Ppp/\Dok1tm1Ppp \Dok2tm1Ppp/\Dok2tm1Ppp |
129S1/Sv-Dok1tm1Ppp Dok2tm1Ppp | J:95334 | View | ||||
| chronic myeloid leukemia |
\Dok1tm1Ppp/\Dok1tm1Ppp \Tg(Tec-BCR/ABL1)5Hhi/0 |
involves: 129S1/Sv | J:95334 | View | ||||
| chronic myeloid leukemia |
\Dok1tm1Yyam/\Dok1tm1Yyam \Dok2tm1Yyam/\Dok2tm1Yyam |
B6.129-Dok1tm1Yyam Dok2tm1Yyam | J:95335 | View | ||||
| chronic myeloid leukemia |
\Dok1tm1Yyam/\Dok1tm1Yyam \Dok2tm1Yyam/\Dok2tm1Yyam \Tg(Tec-BCR/ABL1)5Hhi/0 |
involves: C57BL/6 | J:95335 | View | ||||
| chronic myeloid leukemia |
\Dok1tm1Yyam/\Dok1tm1Yyam \Tg(Tec-BCR/ABL1)5Hhi/0 |
involves: C57BL/6 | J:95335 | View | ||||
| chronic myeloid leukemia |
\Dok2tm1Ppp/\Dok2+ \Tg(Tec-BCR/ABL1)5Hhi/0 |
involves: 129S1/Sv | J:95334 | View | ||||
| chronic myeloid leukemia |
\Dok2tm1Ppp/\Dok2tm1Ppp \Tg(Tec-BCR/ABL1)5Hhi/0 |
involves: 129S1/Sv | J:95334 | View | ||||
| chronic myeloid leukemia |
\Dok2tm1Yyam/\Dok2tm1Yyam \Tg(Tec-BCR/ABL1)5Hhi/0 |
involves: C57BL/6 | J:95335 | View | ||||
| diffuse large B-cell lymphoma |
\Cd19tm1(cre)Cgn/\Cd19+ \Gt(ROSA)26Sortm2(CARD11*L225LI)Jrld/\Gt(ROSA)26Sor+ |
involves: 129P2/OlaHsd | J:228288 | View | ||||
| histiocytic and dendritic cell cancer |
\Cdk5rap2an/\Cdk5rap2an \Tyrp1B-lt/\Tyrp1B-lt |
WBB6F1 | J:160533 | View | ||||
| leukemia |
\Kmt2atm1.1(Sh3gl1)Lcc/\Kmt2a+ \Lyz2tm1(cre)Ifo/\Lyz2+ |
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 | J:205605 | View | ||||
| lymphoid leukemia |
\Col1a1tm4(tetO-GFP/RNAi:Apc)Slowe/\Col1a1+ \Gt(ROSA)26Sortm1(rtTA*M2)Jae/\Gt(ROSA)26Sor+ |
involves: 129S4/SvJae * C57BL/6 | J:171191 | View | ||||
| lymphoma | \Epm2aTg(TcraK,TcrbK)TG-BFlv/\Epm2a+ | involves: C57BL/6 * C57BL/10 * C57BR/cd * CBA/J | J:112696 | View | ||||
| lymphoma |
\Espl1Gt(XL058)Byg/\Espl1+ \Trp53tm1Tyj/\Trp53tm1Tyj |
B6.129-Trp53tm1Tyj Espl1Gt(XL058)Byg | J:174926 | View | ||||
| multiple myeloma |
\Ightm1(Myc)Janz/\Igh+ \Tg(Emu-FGFR3)A5Wmk/0 |
involves: 129X1/SvJ * C57BL/6 * FVB/N | J:160845 | View | ||||
| multiple myeloma |
\Ightm1(Myc)Janz/\Igh+ \Tg(Emu-FGFR3)D3Wmk/0 |
involves: 129X1/SvJ * C57BL/6 * FVB/N | J:160845 | View | ||||
| myelofibrosis |
\Gt(ROSA)26Sortm1(CAG-SETBP1*G870S,-EGFP)Ase/\Gt(ROSA)26Sor+ \Commd10Tg(Vav1-icre)A2Kio/\Commd10+ |
involves: C57BL/6N * C57BL/10 * CBA/Ca | J:363041 | View | ||||
| myeloproliferative neoplasm |
\Col1a1tm2(tetO-GFP/RNAi:Smc1a)Iaai/\Col1a1+ \Gt(ROSA)26Sortm1(rtTA*M2)Jae/\Gt(ROSA)26Sor+ |
involves: 129S4/SvJae * C57BL/6 | J:229031 | View | ||||
| non-Hodgkin lymphoma |
\Gt(ROSA)26Sortm4(Ikbkb)Rsky/\Gt(ROSA)26Sor+ \Ighg1tm1(cre)Cgn/\Ighg1+ \Prdm1tm2Masu/\Prdm1tm2Masu |
involves: 129P2/OlaHsd * C57BL/6 | J:167612 | View | ||||
| non-Hodgkin lymphoma | \Ighmtm1(Bcl6)Rdf/? | involves: 129/Sv * C57BL/6 | J:98937 | View | ||||
|
No similarity to the expected human disease phenotype was found.
|
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | acute myeloid leukemia |
\Krastm4Tyj/\Kras+ \Tg(Mx1-cre)1Cgn/0 |
involves: 129S4/SvJae * C57BL/6 * CBA | J:87429 | View | |||
| acute myeloid leukemia | \Npm1tm1Hft/\Npm1+ | involves: 129 | J:194999 | View | ||||
| essential thrombocythemia | \Jak2tm1.1Jlvl/\Jak2tm1.1Jlvl | involves: 129S2/SvPas * C57BL/6 | J:163497 | View | ||||