Phenotypes Associated with This Genotype

Genotype
MGI:4889198

• Allelic Composition: Tg(CD2-Lmo2)#Thr/0
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:102058 )

• mice die from acute lymphoblastic leukemia unlike wild-type mice

immune system

enlarged thymus ( J:102058 )

enlarged spleen ( J:102058 )

neoplasm

increased acute lymphoblastic leukemia incidence ( J:102058 )

• mice die from acute lymphoblastic leukemia unlike wild-type mice

hematopoietic system

enlarged thymus ( J:102058 )

enlarged spleen ( J:102058 )

endocrine/exocrine glands

enlarged thymus ( J:102058 )

growth/size/body

enlarged spleen ( J:102058 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
acute lymphoblastic leukemia		DOID:9952	OMIM:247640 OMIM:613065	J:102058