acute lymphoblastic leukemia Disease Ontology Browser

Disease Ontology Browser

acute lymphoblastic leukemia (DOID:9952)
Alliance: disease page
Synonyms: acute lymphoblastic leukaemia; acute lymphocytic leukaemia; ALL; precursor lymphoblastic lymphoma/leukemia
Alt IDs: OMIM:247640, OMIM:613065, EFO:0000220, ICD10CM:C91.00, ICD9CM:204.0, NCI:C3167, NCI:C7055, ORDO:513, UMLS_CUI:C0023449, UMLS_CUI:C1335469
Definition: A acute leukemia that is characterized by over production of lymphoblasts.

Term Browser
Genes (77)
Models (19)

Disease References using Mouse Models (20)

Mouse Models

Human Disease Modeled: acute lymphoblastic leukemia

Allelic Composition	Genetic Background	Reference	Phenotypes
Ikzf1tm1Kast/Ikzf1+ Tg(BCR/ABL)623Hkp/0	involves: 129S2/SvPas * C57BL/6 * CBA	J:160846	View

Mouse Models

Human Disease Modeled: acute lymphoblastic leukemia
Associated Mouse Transgene: Tg(CD2-Lmo2)#Thr

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(CD2-Lmo2)#Thr/0	involves: C57BL/6 * CBA	J:102058	View

Mouse Models

Human Disease Modeled: acute lymphoblastic leukemia
Associated Mouse Transgene: Tg(Igh-HMGA2)#Cro

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Igh-HMGA2)#Cro/0	FVB/N-Tg(Igh-HMGA2)#Cro	J:233225	View

Mouse Models

Human Disease Modeled: acute lymphoblastic leukemia
Associated Mouse Transgene: Tg(Lck-Notch3)#Issc

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Lck-Notch3)#Issc/0	involves: C57BL/6 * DBA/2	J:63300	View

Mouse Models

Human Disease Modeled: acute lymphoblastic leukemia
Associated Mouse Gene: Ezh2

Allelic Composition	Genetic Background	Reference	Phenotypes
Ezh2tm2Sho/Ezh2tm2.1Sho Tg(Mx1-cre)1Cgn/0	involves: 129S1/Sv * C57BL/6 * CBA	J:182211	View
Ezh2tm2Sho/Ezh2tm2Sho Tg(Mx1-cre)1Cgn/0	involves: 129S1/Sv * C57BL/6 * CBA	J:182211	View

Mouse Models

Human Disease Modeled: acute lymphoblastic leukemia
Associated Mouse Gene: Kmt2a

Allelic Composition	Genetic Background	Reference	Phenotypes
Kmt2atm1Saam/Kmt2a+ Tg(Mx1-cre)1Cgn/0	involves: 129S1/Sv * C57BL/6 * CBA	J:140628	View

Mouse Models

Human Disease Modeled: acute lymphoblastic leukemia
Associated Mouse Gene: Pten

Allelic Composition	Genetic Background	Reference	Phenotypes
Ptentm1Hwu/Ptentm1Hwu Tg(Mx1-cre)1Cgn/0	involves: 129S4/SvJae * C57BL/6 * CBA	J:169097	View

Mouse Models

Human Disease Modeled: acute lymphoblastic leukemia

Allelic Composition	Genetic Background	Reference	Phenotypes
Tcf3tm1(PBX1)Mlc/Tcf3+ Cd19tm1(cre)Cgn/Cd19+	involves: 129P2/OlaHsd * C57BL/6	J:226241	View

Mouse Models

Human Disease Modeled: acute lymphoblastic leukemia

Allelic Composition	Genetic Background	Reference	Phenotypes
Tcf3tm1(PBX1)Mlc/Tcf3+ Cd79atm1(cre)Reth/Cd79a+	involves: BALB/c * C57BL/6	J:226241	View

Mouse Models

Human Disease Modeled: acute lymphoblastic leukemia

Allelic Composition	Genetic Background	Reference	Phenotypes
Tcf3tm1(PBX1)Mlc/Tcf3+ Tg(Mx1-cre)1Cgn/0	involves: C57BL/6 * C57BL/6J * CBA/J	J:226241	View

Mouse Models

Human Disease Modeled: acute lymphoblastic leukemia

Allelic Composition	Genetic Background	Reference	Phenotypes
Zfp36l1tm1.1Tnr/Zfp36l1tm1.1Tnr Zfp36l2tm1.1Tnr/Zfp36l2tm1.1Tnr Tg(CD2-icre)4Kio/0	involves: C57BL/6 * C57BL/10 * CBA/Ca * SJL	J:162388	View

Mouse Models

Human Disease Modeled: acute lymphoblastic leukemia

Allelic Composition	Genetic Background	Reference	Phenotypes
Etv6tm1.1(RUNX1,hsb5)Lvdw/Etv6+ TgTn(sb-T2/Onc)76Dla/0	involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/N	J:174866	View

Mouse Models

Human Disease Modeled: acute lymphoblastic leukemia

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Lck-LMO1)11Sjk/0 Tg(STIL-TAL1)A5(3)Alpa/0	involves: C3H * C3H/HeRos * C57BL/6 * C57BL/10Ros	J:40868	View

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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