Excel File Text File All mouse models of primary immunodeficiency disease with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      adenosine deaminase deficiency Adatm1Mw/Adatm1Mw
Tg(PLADA)4118Rkmb/0		 involves: 129S7/SvEvBrd * C57BL/6 J:73418 View
atypical hemolytic-uremic syndrome Cfhtm1.1Song/Cfhtm1.1Song involves: C57BL/6 J:240426 View
autoimmune interstitial lung, joint, and kidney disease Copatm1.1Shum/Copa+ B6(CBA)-Copatm1.1Shum J:288425 View
chronic granulomatous disease Cybbtm1Din/Cybbtm1Din B6.129S-Cybbtm1Din J:146231 View
chronic granulomatous disease Cybbtm1Din/Y involves: 129S/SvEv * C57BL/6 J:22868 View
chronic granulomatous disease Ncf1m1J/Ncf1m1J B6.Cg-Dock7m +/+ Leprdb/J J:83428 View
chronic granulomatous disease Ncf1tm1Hbd/Ncf1tm1Hbd involves: 129 J:74593 View
chronic granulomatous disease Ncf1tm1Shl/Ncf1tm1Shl B6.129S2-Ncf1tm1Shl J:111142 View
chronic granulomatous disease Ncf1tm1Shl/Ncf1tm1Shl involves: 129S2/SvPas * C57BL/6J J:28267 View
complement component 3 deficiency C3tm1Crr/C3tm1Crr involves: 129S4/SvJae * C57BL/6 J:30152 View
complement component 3 deficiency C3tm1Hrc/C3tm1Hrc either: (involves: 129S2/SvPas * C57BL/6) or (involves: 129X1/SvJ * C57BL/6) J:56193 View
complement component 3 deficiency C3tm1Pkna/C3tm1Pkna involves: 129P2/OlaHsd * C57BL/6 J:45857 View
DNA ligase IV deficiency Lig4tiny/Lig4tiny C57BL/6-Lig4tiny J:122725 View
DNA ligase IV deficiency Lig4tm2.1Fwa/Lig4tm2.1Fwa involves: 129S6/SvEvTac J:157574 View
familial cold autoinflammatory syndrome 1 Nlrp3tm2Hhf/Nlrp3+
Lyz2tm1(cre)Ifo/Lyz2+		 involves: 129/Sv * 129P2/OlaHsd * C57BL/6 J:150054 View
familial cold autoinflammatory syndrome 1 Nlrp3tm2Hhf/Nlrp3+
Tg(CAG-cre/Esr1*)5Amc/?		 involves: 129/Sv * C57BL/6 * CBA J:150054 View
familial cold autoinflammatory syndrome 4 Tg(Cd74-Nlrc4*)1Kyas/0 involves: C57BL/6N J:219652 View
familial Mediterranean fever Mefvtm1Chae/Mefvtm1Chae either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6) J:82763 View
familial Mediterranean fever Mefvtm3.1(MEFV)Chae/Mefvtm3.1(MEFV)Chae B6.129S6-Mefvtm3.1(MEFV)Chae J:172117 View
familial Mediterranean fever Mefvtm4.1(MEFV)Chae/Mefvtm4.1(MEFV)Chae B6.129S6-Mefvtm4.1(MEFV)Chae J:172117 View
familial Mediterranean fever Mefvtm5.1(MEFV)Chae/Mefvtm5.1(MEFV)Chae B6.129S6-Mefvtm5.1(MEFV)Chae J:172117 View
hyper IgE recurrent infection syndrome 1 Tg(Stat3*)9199Alau/0 involves: C57BL/6 J:210877 View
immunodeficiency 14 Pik3cdem1.1Pls/Pik3cd+ Not Specified J:282486 View
immunodeficiency 15A Ikbkbem1Macc/Ikbkb+ involves: C57BL/6NCrl J:290616 View
immunodeficiency 15A Ikbkbem1Macc/Ikbkbem1Macc involves: C57BL/6NCrl J:290616 View
immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia Rac2em1Shl/Rac2+ involves: C57BL/6 J:276213 View
immunodeficiency with hyper-IgM type 2 Aicdaem1Jaych/Aicdaem1Jaych involves: C57BL/6J J:305843 View
leukocyte adhesion deficiency 1 Itgb2tm1Bay/Itgb2tm1Bay involves: 129S7/SvEvBrd J:13599 View
leukocyte adhesion deficiency 1 Itgb2tm1Bay/Itgb2tm1Bay involves: 129S7/SvEvBrd * C57BL/6J J:13599 View
leukocyte adhesion deficiency 1 Itgb2tm2Bay/Itgb2tm2Bay involves: 129S7/SvEvBrd * C57BL/6J J:48542 View
leukocyte adhesion deficiency 3 Fermt3tm1Ref/Fermt3tm1Ref involves: 129S1/Sv * 129X1/SvJ J:146783 View
MHC class II deficiency Ciitatm1Ccum/Ciitatm1Ccum involves: 129S2/SvPas * C57BL/6J J:31601 View
MHC class II deficiency Ciitatm2Wrth/Ciitatm2Wrth involves: 129P2/OlaHsd * C57BL/6 J:92170 View
Omenn syndrome Rag2tm1Avla/Rag2tm1Avla involves: 129/Sv * C57BL/6 J:122108 View
psoriasis Tg(KRT5-Stat3*A661C*N663C)1Jdg/0 involves: FVB J:95458 View
psoriasis Tg(KRT14-Vegfa)3Dtm/0 FVB/N-Tg(KRT14-Vegfa)3Dtm J:92643 View
psoriasis 2 Card14em2Tshu/Card14+ involves: C57BL/6 J:289239 View
psoriasis 2 Card14em9Lutzy/Card14+ C57BL/6J-Card14em9Lutzy/J J:262723 View
purine nucleoside phosphorylase deficiency Pnpe/Pnpe C57BL/6J-Pnpe J:39328 View
purine nucleoside phosphorylase deficiency Pnpe/Pnpe involves: C3H/HeHa * C57BL/6J J:23354 View
purine nucleoside phosphorylase deficiency Pnpf/Pnpf C57BL/6J-Pnpf J:39328 View
purine nucleoside phosphorylase deficiency Pnpf/Pnpf involves: C3H/HeHa * C57BL/6J J:23354 View
purine nucleoside phosphorylase deficiency Pnpg/Pnpg involves: C57BL/6 * DBA/2J J:39328 View
rheumatoid arthritis TnfBpsm1/Tnf+ involves: C57BL/6 J:226052 View
rheumatoid arthritis TnfBpsm1/TnfBpsm1 involves: C57BL/6 J:226052 View
rheumatoid arthritis Tnftm1Gkl/Tnftm2Gkl involves: 129S/SvEv * C57BL/6 J:54056 View
rheumatoid arthritis Tnftm2Gkl/Tnf+ involves: 129S/SvEv * C57BL/6 J:54056 View
rheumatoid arthritis Tnftm2Gkl/Tnf+ involves: 129S/SvEv * C57BL/6J J:264147 View
rheumatoid arthritis Tnftm2Gkl/Tnftm2Gkl involves: 129S/SvEv * C57BL/6 J:54056 View
severe combined immunodeficiency with sensitivity to ionizing radiation Dclre1ctm1Jsek/Dclre1ctm1Jsek involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:147864 View
severe combined immunodeficiency with sensitivity to ionizing radiation Dclre1ctm2Mcow/Dclre1ctm2Mcow involves: 129/Sv * C57BL/6 J:96535 View
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive Rag2tm1Fwa/Rag2tm1Fwa involves: 129S/SvEv * MF1 J:1935 View
T-cell immunodeficiency, congenital alopecia, and nail dystrophy Foxn1nu-2J/Foxn1nu-2J B6(SJL)-Foxn1nu-2J/GrsrJ J:222308 View
T-cell immunodeficiency, congenital alopecia, and nail dystrophy Foxn1nu-Y/Foxn1nu-Y 101/HY-Foxn1nu-Y J:29022 View
T-cell immunodeficiency, congenital alopecia, and nail dystrophy Foxn1nu/Foxn1nu Not Specified J:11959 View
T-cell immunodeficiency, congenital alopecia, and nail dystrophy Foxn1tm1Tbo/Foxn1tm1Tbo involves: 129S1/Sv J:33796 View
TNF receptor associated periodic syndrome Tnfrsf1atm1Imx/Tnfrsf1atm1Imx involves: 129S7/SvEvBrd * C57BL/6 J:45147 View
TNF receptor associated periodic syndrome Tnfrsf1atm1Rsie/Tnfrsf1a+ B6.Cg-Tnfrsf1atm1Rsie J:160543 View
TNF receptor associated periodic syndrome Tnfrsf1atm2.1Rsie/Tnfrsf1a+ B6.Cg-Tnfrsf1atm2.1Rsie J:160543 View
type 1 diabetes mellitus Cd38tm1Lnd/Cd38tm1Lnd NOD.129P2(B6)-Cd38tm1Lnd/LtJ J:108097 View
type 1 diabetes mellitus Gad2tm1Miya/Gad2tm1Miya NOD.129P2-Gad2tm1Miya J:88785 View
type 1 diabetes mellitus H2g7/H2g7
Ins2tm1Jja/Ins2tm1Jja
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraBDC12-4.1)10Jos/0
Tg(TcrbBDC12-4.1)82Gse/0		 involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 * FVB * NOD J:111874 View
type 1 diabetes mellitus Il1r1tm1Roml/Il1r1tm1Roml NOD.Cg-Il1r1tm1Roml J:87251 View
type 1 diabetes mellitus Ins1tm1Jja/Ins1tm1Jja
Tg(Ins2*Y16A)1Ell/0		 NOD.Cg-Ins1tm1Jja Tg(Ins2*Y16A)1Ell J:98583 View
type 1 diabetes mellitus Ins2Akita/Ins2Akita C.B6N-Ins2Akita J:198186 View
type 1 diabetes mellitus Ins2Akita/Ins2Akita
Itga1tm1Gdnr/Itga1tm1Gdnr		 C.Cg-Ins2Akita Itga1tm1Gdnr J:198186 View
type 1 diabetes mellitus Ins2tm1Jja/Ins2tm1Jja NOD.129S2-Ins2tm1Jja J:85309 View
type 1 diabetes mellitus Ptprn2tm1Aln/Ptprn2tm1Aln involves: 129S4/SvJae * C57BL/6N * NOD/LtJ J:81889 View
type 1 diabetes mellitus Tg(H2-Ea-Ins2)1Wehi/0 NOD/ShiLtJWehi-Tg(H2-Ea-Ins2)1Wehi J:100251 View
WHIM syndrome 1 Cxcr4tm1.1Bala/Cxcr4+ B6.129S2-Cxcr4tm1.1Bala J:186735 View
X-linked agammaglobulinemia Blnktm1Pjln/Blnktm1Pjln
Btktm1Wk/Btktm1Wk		 involves: 129S4/SvJae * BALB/c * C57BL/6 J:70406 View
X-linked agammaglobulinemia Btktm1Gsv/Y involves: 129P2/OlaHsd * C57BL/6 J:35769 View
X-linked agammaglobulinemia Btktm1Wk/Btktm1Wk involves: 129S4/SvJae * C57BL/6 J:28968 View
X-linked agammaglobulinemia Btktm1Wk/Btktm1Wk
Tectm1Welm/Tectm1Welm		 involves: 129P2/OlaHsd * C57BL/6 J:66080 View
X-linked agammaglobulinemia Btkxid/Btkxid CBA/HN-Btkxid J:81429 View
X-linked agammaglobulinemia Btkxid/Btkxid involves: CBA/HN * DBA/2N J:81429 View
X-linked agammaglobulinemia Btkxid/Y CBA/HN-Btkxid J:81429 View
X-linked agammaglobulinemia Btkxid/Y involves: CBA/HN * DBA/2N J:81429 View
X-linked lymphoproliferative syndrome 1 Sh2d1atm1Cpt/Sh2d1atm1Cpt B6.129S4-Sh2d1atm1Cpt J:97388, J:97690 View
X-linked lymphoproliferative syndrome 1 Sh2d1atm1Cpt/Sh2d1atm1Cpt C.129S4-Sh2d1atm1Cpt J:97388 View
X-linked lymphoproliferative syndrome 1 Sh2d1atm1Cpt/Sh2d1atm1Cpt involves: 129S4/SvJae * BALB/c J:97756 View
X-linked lymphoproliferative syndrome 1 Sh2d1atm1Cpt/Sh2d1atm1Cpt involves: 129S4/SvJae * C57BL/6 J:97756 View
X-linked lymphoproliferative syndrome 1 Sh2d1atm1Lyin/Sh2d1atm1Lyin involves: 129S2/SvPas * C57BL/6 J:97346 View
X-linked lymphoproliferative syndrome 1 Sh2d1atm1Lyin/Y involves: 129S2/SvPas * C57BL/6 J:97346 View
X-linked lymphoproliferative syndrome 1 Sh2d1atm1Pls/Sh2d1atm1Pls either: 129S6/SvEvTac or (involves: 129S6/SvEvTac * C57BL/6) J:70032 View
      autoimmune hemolytic anemia Tg(KRT5-rtTA)1Glk/0
Tg(tetO/CMV-Tslp)#Sfz/0		 C.Cg-Tg(KRT5-rtTA)1Glk Tg(tetO/CMV-Tslp)#Sfz J:182756 View
combined immunodeficiency Copg1em1Geha/Copg1em1Geha involves: C57BL/6 J:345528 View
common variable immunodeficiency Icostm1Flv/Icostm1Flv involves: 129/Sv * C57BL/6 J:87123 View
common variable immunodeficiency Icostm1Shr/Icostm1Shr Not Specified J:87124 View
common variable immunodeficiency Nfkb2Lym1/Nfkb2+ BALB/c-Nfkb2Lym1 J:206674 View
common variable immunodeficiency Nfkb2Lym1/Nfkb2Lym1 involves: BALB/c J:206674 View
common variable immunodeficiency Nfkb2tm2Brv/Nfkb2tm2Brv involves: 129S1/Sv * C57BL/6 J:206674 View
Lambert-Eaton myasthenic syndrome Cacna1atg-rol/Cacna1atg-rol involves: C57BL/6 * SIII J:164115 View
leukocyte adhesion deficiency 3 Rasgrp2tm1Amg/Rasgrp2tm1Amg Not Specified J:122618 View
primary biliary cholangitis Map3k14aly/Map3k14aly involves: C57BL/6J J:48224 View
primary biliary cholangitis Zc3h12atm1c(EUCOMM)Hmgu/Zc3h12atm1c(EUCOMM)Hmgu
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+		 involves: C57BL/6 * C57BL/6N * DBA J:304105 View
primary immunodeficiency disease Magt1Gt(IST13422E1)Tigm/Y involves: C57BL/6N J:260923 View
psoriasis Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi
Krt14tm1(cre)Wbm/Krt14+		 B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm J:253986 View
psoriasis Itgb2tm1Bay/Itgb2tm1Bay involves: 129S7/SvEvBrd * C57BL/6J * PL/J J:32126, J:84126 View
psoriasis Itgb2tm1Bay/Itgb2tm1Bay involves: 129S7/SvEvBrd * PL/J J:32126, J:109598 View
psoriasis Itgb2tm1Bay/Itgb2tm2Bay involves: 129S7/SvEvBrd * C57BL/6J * PL/J J:84126 View
psoriasis Itgb2tm1Bay/Itgb2tm2Bay PL.129S7-Itgb2tm1Bay Itgb2tm2Bay J:84126 View
psoriasis Itgb2tm2Bay/Itgb2tm2Bay involves: 129S7/SvEvBrd * PL/J J:84126 View
psoriasis Sptlc2tm1Yhir/Sptlc2tm1Yhir
Tg(KRT5-cre)1Tak/0		 involves: C3H * C57BL/6 J:202388 View
psoriasis Tg(KRT5-rtTA)#Glk/0
Tg(tetO-S100a7a)#Yus/0		 involves: FVB/N J:168000 View
psoriasis Ttc7fsn/Ttc7fsn involves: A/J * BALB/cByJ J:14506 View
rheumatoid arthritis Dnase2atm1Osa/Dnase2atm1Osa
Ifnar1tm1Agt/Ifnar1tm1Agt		 involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 J:114982, J:238323 View
rheumatoid arthritis Dnase2atm1Osa/Dnase2atm2Osa
Tg(Mx1-cre)1Cgn/0		 involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * CBA J:114982 View
rheumatoid arthritis Il6sttm1Thir/Il6sttm1Thir involves: 129 * C57BL/6 J:133059 View
rheumatoid arthritis Mmp14tm1Hbh/Mmp14tm1Hbh involves: 129P2/OlaHsd * Black Swiss J:57969 View
rheumatoid arthritis Zap70m1Saka/Zap70m1Saka involves: BALB/c J:86607 View
rheumatoid arthritis Zfp36tm1Pjb/Zfp36tm1Pjb B6.Cg-Zfp36tm1Pjb J:214114 View
severe combined immunodeficiency 104 Coro1akoy/Coro1akoy C57BL/6-Coro1akoy J:141431 View
severe combined immunodeficiency 104 Coro1aptcd/Coro1aptcd B6.CTS-Coro1aptcd J:141431 View
severe combined immunodeficiency 104 Coro1aptcd/Coro1atm1Achn B6.Cg-Coro1aptcd Coro1atm1Achn J:141431 View
severe combined immunodeficiency 104 Coro1atm1Achn/Coro1atm1Achn B6.129X1-Coro1atm1Achn J:141431 View
severe combined immunodeficiency 104 Jak3tm1Ljb/Jak3tm1Ljb involves: 129S4/SvJae J:64861 View
severe combined immunodeficiency 104 Jak3tm1Tks/Jak3tm1Tks involves: 129P2/OlaHsd * C57BL/6 J:31231 View
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive Prkdcscid/Prkdcscid C.BKa-Prkdcscid J:6958 View
type 1 diabetes mellitus Agertm1.1Hyam/Agertm1.1Hyam
Tg(Ins2-Nos2)40Okam/0		 involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA/2 J:116040 View
type 1 diabetes mellitus Cdk4tm1Bbd/Cdk4tm1Bbd involves: 129S1/Sv * 129X1/SvJ * ICR J:54534 View
type 1 diabetes mellitus E2f1tm1Meg/E2f1tm1Meg NOD.Cg-E2f1tm1Meg J:93708 View
type 1 diabetes mellitus Faslpr/Faslpr
Tg(Ins2-Fasl)24Ach/0		 NOD.Cg-Faslpr Tg(Ins2-Fasl)24Ach J:81416 View
type 1 diabetes mellitus Ifngtm1Ts/Ifngtm1Ts NOD.129S7(B6)-Ifngtm1Ts/DvsJ J:72818 View
type 1 diabetes mellitus Ifngtm1Ts/Ifngtm1Ts NOD.Cg-Ifngtm1Ts Prkdcscid J:72818 View
type 1 diabetes mellitus Ifngr2tm1Pbro/Ifngr2tm1Pbro NOD.129S1-Ifngr2tm1Pbro J:72818 View
type 1 diabetes mellitus Ighmtm1Cgn/Ighm+ NOD.129S2-Ighmtm1Cgn J:37287 View
type 1 diabetes mellitus Ighmtm1Cgn/Ighm+
Tg(Igh-6/Igh-V281)3Jwt/0		 NOD.Cg-Ighmtm1Cgn Tg(Igh-6/Igh-V281)3Jwt J:91865 View
type 1 diabetes mellitus Ighmtm1Cgn/Ighmtm1Cgn
Tg(Igh-VB1-8/Igh-6m)1Mjsk/?		 NODCaj.Cg-Ighmtm1Cgn Tg(Igh-VB1-8/Igh-6m)1Mjsk/FswJ J:93190 View
type 1 diabetes mellitus Il4tm1Cgn/Il4tm1Cgn either: NOD.129-Il4tm1Cgn or (involves: 129 * NOD) J:85924 View
type 1 diabetes mellitus Il4tm1Cgn/Il4tm1Cgn
Tg(TcraBDC2.5,TcrbBDC2.5)1Doi/0		 NOD.Cg-Il4tm1Cgn Tg(TcraBDC2.5,TcrbBDC2.5)1Doi J:85924 View
type 1 diabetes mellitus Irak3tm1Flv/Irak3tm1Flv NOD.129S1(B6)-Irak3tm1Flv J:229884 View
type 1 diabetes mellitus Mbd2tm1Bh/Mbd2tm1Bh NOD.129P2(B6)-Mbd2tm1Bh J:323838 View
type 1 diabetes mellitus Pdx1tm1Cvw/Pdx1tm4Cvw
Tg(Ins2-cre)25Mgn/0		 involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 * DBA J:130389 View
type 1 diabetes mellitus Prf1tm1Clrk/Prf1tm1Clrk involves: 129S7/SvEvBrd * BALB/c * NOD J:64051 View
type 1 diabetes mellitus Prf1tm1Clrk/Prf1tm1Clrk
Tg(INS-Il10)#Sar/0		 involves: 129S7/SvEvBrd * BALB/c * NOD J:64051 View
type 1 diabetes mellitus Selltm1Flv/Sell+ involves: C57BL/6 * NOD J:88974 View
type 1 diabetes mellitus Selltm1Flv/Sell+ NOD.Cg-Selltm1Flv J:88974 View
type 1 diabetes mellitus Selltm1Flv/Selltm1Flv involves: C57BL/6 * NOD J:88974 View
type 1 diabetes mellitus Selltm1Flv/Selltm1Flv NOD.Cg-Selltm1Flv J:88974 View
type 1 diabetes mellitus Senp1tm1Wami/Senp1tm1Wami
Tg(Fabp4-cre)#Abel/0		 B6.Cg-Senp1tm1Wami Tg(Fabp4-cre)#Abel J:228009 View
type 1 diabetes mellitus Stat4tm1Gru/Stat4+ NOD.129S2-Stat4tm1Gru J:90600 View
type 1 diabetes mellitus Stat4tm1Gru/Stat4tm1Gru C.129S2-Stat4tm1Gru J:106340 View
type 1 diabetes mellitus Stat4tm1Gru/Stat4tm1Gru
Tg(Ins2-GP)34-20Olds/0		 involves: 129S2/SvPas * BALB/c * C57BL/6 J:107047 View
type 1 diabetes mellitus Stat4tm1Gru/Stat4tm1Gru
Tg(Ins2-NP)25-3Olds/0		 involves: 129S2/SvPas * BALB/c * C57BL/6 J:107047 View
type 1 diabetes mellitus Tg(H2-Ea-G6pc2)69Tkay/? NOD-Tg(H2-Ea-G6pc2)69Tkay J:117352 View
type 1 diabetes mellitus Tg(Igh-6/Igh-V125)2Jwt/0
Tg(Igk-C/Igk-V125)1Jwt/0		 NOD.B6-Tg(Igh-6/Igh-V125)2Jwt Tg(Igk-C/Igk-V125)1Jwt J:91865 View
type 1 diabetes mellitus Tg(Igh-6/Igh-V281)3Jwt/0 NOD.B6-Tg(Igh-6/Igh-V281)3Jwt J:91865 View
type 1 diabetes mellitus Tg(Ins2-Fas*I246N)1Ach/0
Tg(Ins2-Fasl)24Ach/0		 NOD-Tg(Ins2-Fas*I246N)1Ach Tg(Ins2-Fasl)24Ach J:81416 View
type 1 diabetes mellitus Tg(Ins2-Fasl)24Ach/0 NOD-Tg(Ins2-Fasl)24Ach/J J:78679 View
type 1 diabetes mellitus Tg(Ins2-Nos2)31Okam/0 involves: C57BL/6 * CD-1 * DBA/2 J:45520 View
type 1 diabetes mellitus Tg(Ins2-Nos2)40Okam/0 involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA/2 J:116040 View
type 1 diabetes mellitus Tg(Ins2-Nos2)40Okam/0 involves: C57BL/6 * CD-1 * DBA/2 J:4552 View
type 1 diabetes mellitus Tg(Ins2-Nos2)40Okam/0
Tg(Kdr-AGER)102Hyam/0		 involves: C57BL/6J * CBA/J * CD-1 * DBA/2 J:70495 View
type 1 diabetes mellitus Tnfsf4tm1Shr/Tnfsf4tm1Shr NOD.129S4-Tnfsf4tm1Shr J:86926 View
type 1 diabetes mellitus 2 Apobtm2Sgy/Apobtm2Sgy
Ldlrtm1Her/Ldlrtm1Her
Tg(Ins-Igf2)1Fbos/?		 involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL J:227165 View
type 1 diabetes mellitus 2 Tg(Ins-Igf2)1Fbos/0 involves: C57BL/6 * C57BLKs/J * SJL J:141527 View
type 1 diabetes mellitus 2 Tg(Ins-Igf2)1Fbos/0 involves: C57BL/6 * SJL J:141527 View
type 1 diabetes mellitus 7 Neurod1tm1Mjts/Neurod1tm1Mjts involves: 129S7/SvEvBrd * C57BL/6 J:43010 View
X-linked agammaglobulinemia Pik3r1tm1Dfr/Pik3r1tm1Dfr involves: 129S6/SvEvTac * C57BL/6 J:52229, J:65523 View
X-linked agammaglobulinemia Pik3r1tm1Tka/Pik3r1tm1Tka involves: C57BL/6 * CBA J:52228 View
      type 1 diabetes mellitus Cd80tm1Shr/Cd80tm1Shr
Cd86tm2Shr/Cd86tm2Shr		 involves: 129S4/SvJae * NOD J:61905 View
type 1 diabetes mellitus H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Tg(HLA-DQA1,HLA-DQB1)1Dv/0
Tg(HLA-DRB1)31Dmz/0
Tg(Ins2-CD80)3B7Flv/0		 involves: 129S2/SvPas * C57BL/6 * C57BL/10SnJ * CBA * SJL J:68641 View
type 1 diabetes mellitus H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Tg(HLA-DQA1,HLA-DQB1)1Dv/0
Tg(Ins2-CD80)3B7Flv/0		 B6.Cg-H2-Ab1b-tm1Gru Tg(HLA-DQA1,HLA-DQB1)1Dv Tg(Ins2-CD80)3B7Flv J:59245 View
type 1 diabetes mellitus H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Tg(HLA-DRB1)31Dmz/0
Tg(Ins2-CD80)3B7Flv/0		 involves: 129S2/SvPas * C57BL/6 * CBA * SJL J:68641 View
type 1 diabetes mellitus Tg(Ins1-Cd80)378Psoh/0
Tg(Ins2-GP)#Psoh/0
Tg(TcrLCMV)327Sdz/0		 involves: C57BL/6 * DBA/2 * FVB/N J:209714 View
Transgenes and
Other Mutations		     psoriasis Tg(CAG-Lyn*)#Paau/0 B6.Cg-Tg(CAG-Lyn*)#Paau J:151886 View
psoriasis Tg(CYP1A1-PPARD)#Jfoe/0 involves: C57BL/6J * CBA J:158907 View
psoriasis Tg(ITGA2)1067Fmw/0
Tg(ITGB1)0840Fmw/0		 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1067Fmw/0
Tg(ITGB1)0869Fmw/0		 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1067Fmw/0
Tg(ITGB1)0870Fmw/0		 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1070Fmw/0
Tg(ITGB1)0840Fmw/0		 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1070Fmw/0
Tg(ITGB1)0869Fmw/0		 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1070Fmw/0
Tg(ITGB1)0870Fmw/0		 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1075Fmw/0
Tg(ITGB1)0840Fmw/0		 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1075Fmw/0
Tg(ITGB1)0869Fmw/0		 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA2)1075Fmw/0
Tg(ITGB1)0870Fmw/0		 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0794Fmw/0
Tg(ITGB1)0840Fmw/0		 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0794Fmw/0
Tg(ITGB1)0869Fmw/0		 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0794Fmw/0
Tg(ITGB1)0870Fmw/0		 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0844Fmw/0
Tg(ITGB1)0840Fmw/0		 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0844Fmw/0
Tg(ITGB1)0869Fmw/0		 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0844Fmw/0
Tg(ITGB1)0870Fmw/0		 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0858Fmw/0
Tg(ITGB1)0840Fmw/0		 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0858Fmw/0
Tg(ITGB1)0869Fmw/0		 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGA5)0858Fmw/0
Tg(ITGB1)0870Fmw/0		 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGB1)0840Fmw/0 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGB1)0869Fmw/0 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(ITGB1)0870Fmw/0 involves: C57BL/10 * CBA J:30249 View
psoriasis Tg(KRT5-TGFB1)F2020Xjw/0 involves: C57BL/6 * DBA/2 * ICR J:90118 View
psoriasis Tg(KRT5-tTA)1216Glk/0
Tg(tetO-Tek)1Dmt/0		 involves: CD-1 * FVB/N J:147438 View
psoriasis Tg(Krt14-Rac1*G12V)#Mrnk/0 either: B6.CBACa-Tg(Krt14-Rac1*G12V)#Mrnk or C.CBACa-Tg(Krt14-Rac1*G12V)#Mrnk J:237134 View
psoriasis Tg(Krt14-Rac1*G12V)#Mrnk/0 involves: CBA/CaJ J:237134 View
psoriasis Tg(Tek-tTA)1Dmt/0
Tg(tetO-Tek)1Dmt/0		 involves: CD-1 J:96718 View
rheumatoid arthritis H2b/H2g7
Tg(TcraR28,TcrbR28)KRNDim/0		 involves: C57BL/6 * NOD * SJL J:36815 View
rheumatoid arthritis Tg(CAG-SYVN1)1Tn/? D1.Cg-Tg(CAG-SYVN1)1Tn J:86009 View
rheumatoid arthritis Tg(FCGR2A)11Mkz/Tg(FCGR2A)11Mkz involves: C57BL/6 * SJL J:136516 View
rheumatoid arthritis Tg(HLA-DRA*0101,HLA-DRB1*0101)1Dmz/Tg(HLA-DRA*0101,HLA-DRB1*0101)1Dmz involves: C57BL/6 * C57BL/10Sn * SJL/J J:108635 View
rheumatoid arthritis Tg(TcraR28,TcrbR28)KRNDim/0 involves: C57BL/6 * NOD * SJL J:36815 View
rheumatoid arthritis Tg(TNF)197Gkl/0 involves: C57BL/6 * CBA J:92576 View
rheumatoid arthritis Tg(TNF)3647Gkl/0 involves: C57BL/6 * CBA J:190204 View
type 1 diabetes mellitus B2mtm1Unc/B2mtm1Unc
Tg(HLA-A/H2-D/B2M)1Dvs/0		 NOD.Cg-B2mtm1Unc Tg(HLA-A/H2-D/B2M)1Dvs J:121685 View
type 1 diabetes mellitus Cd4tm1Knw/Cd4tm1Knw
Tg(TcraAI4)1Dvs/0
Tg(TcrbAI4)1Dvs/0		 NOD.Cg-Cd4tm1Knw Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs J:93553 View
type 1 diabetes mellitus Fastm1Vbo/Fastm1Vbo
Tg(Ins2-cre)25Mgn/0
Tg(Ins2-HA)165Bri/0
Tg(Tcra/Tcrb)1Vbo/0		 Not Specified J:85985 View
type 1 diabetes mellitus H2g7/H2g7
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraBDC12-4.1)10Jos/0
Tg(TcrbBDC12-4.1)82Gse/0		 involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD J:111874 View
type 1 diabetes mellitus H2g7/H2q
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraBDC12-4.1)10Jos/0
Tg(TcrbBDC12-4.1)82Gse/0		 involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD J:111874 View
type 1 diabetes mellitus Prkdcscid/Prkdcscid
Tg(TcraAI4)1Dvs/0
Tg(TcrbAI4)1Dvs/0		 NOD.Cg-Prkdcscid Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs J:93553 View
type 1 diabetes mellitus Rag1tm1Mom/Rag1tm1Mom
Tg(TcraAI4)1Dvs/0
Tg(TcrbAI4)1Dvs/0		 NOD.Cg-Rag1tm1Mom Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs/Dvs J:94192 View
type 1 diabetes mellitus Rag1tm1Mom/Rag1tm1Mom
Tg(TcraBDC12-4.1)10Jos/0
Tg(TcrbBDC12-4.1)82Gse/0		 involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD J:111874 View
type 1 diabetes mellitus Tg(Cryaa-TAg,Ins2-CALM1)26Ove/0 FVB(Cg)-Tg(Cryaa-Tag,Ins2-CALM1)26Ove/PneJ J:97926 View
type 1 diabetes mellitus Tg(Cryaa-TAg,Ins2-CALM1)26Ove/0 FVB-Tg(Cryaa-TAg,Ins2-CALM1)26Ove J:94602 View
type 1 diabetes mellitus Tg(H2-Ead)12Lt/0 NOD/ShiLt-Tg(H2-Ead)12Lt J:36435 View
type 1 diabetes mellitus Tg(HLA-A/H2-D/B2M)1Dvs/0 NOD/ShiLtDvs-Tg(HLA-A/H2-D/B2M)1Dvs J:121685 View
type 1 diabetes mellitus Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg NOD.B6-Tg(IghelMD4)4Ccg/DvsJ J:80859 View
type 1 diabetes mellitus Tg(Ins1-Cat,Tyr)25Pne/0 involves: FVB J:59725 View
type 1 diabetes mellitus Tg(Ins1-Cat,Tyr)25Pne/0 NOD.FVB-Tg(Ins1-Cat,Tyr)25Pne J:108415 View
type 1 diabetes mellitus Tg(Ins2*Y16A)3Ell/0 NOD-Tg(Ins2*Y16A)3Ell J:98583 View
type 1 diabetes mellitus Tg(Ins2-CD80)3B7Flv/? involves: C57BL/6 * CBA/Ca * NOD/Caj J:26618 View
type 1 diabetes mellitus Tg(Ins2-GP)34-20Olds/0 involves: BALB/c * C57BL/6 J:81287 View
type 1 diabetes mellitus Tg(Ins2-HBEGF)5Rin/? C57BL/6-Tg(Ins2-HBEGF)5Rin J:204420 View
type 1 diabetes mellitus Tg(Ins2-NP)25-3Olds/0 involves: BALB/c * C57BL/6 J:81284 View
type 1 diabetes mellitus Tg(INS-MT2A,Tyr)1Pne/0 FVB-Tg(INS-MT2A,Tyr)1Pne J:100251 View
type 1 diabetes mellitus Tg(INS-MT2A,Tyr)1Pne/0 NOD.FVB-Tg(INS-MT2A,Tyr)1Pne J:108415 View
type 1 diabetes mellitus Tg(INS-SOD2)3Pne/0 NOD.FVB-Tg(INS-SOD2)3Pne J:108415 View
type 1 diabetes mellitus Tg(TcraAI4)1Dvs/0 NOD-Tg(TcraAI4)1Dvs J:93553 View
type 1 diabetes mellitus Tg(TcraAI4)1Dvs/0
Tg(TcrbAI4)1Dvs/0		 NOD-Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs J:93553 View
type 1 diabetes mellitus Tg(TcraTcrbNY8.3)1Pesa/? involves: C57BL/6 * NOD * SJL J:44202 View
Additional
Complex
Models		     autoimmune hemolytic anemia Tg(SV40-Igh-64C8)H3Hon/0
Tg(SV40-Igk4C8)L1Hon/0		 involves: C57BL/6 J:139864 View
hyper IgE recurrent infection syndrome 1 Igh-Jtm1Mcdl/Igh-Jtm1Mcdl
Igk-Jtm1Mcdl/Igk-Jtm1Mcdl
Rag1tm1Mom/Rag1tm1Mom
Tg(DO11.10)10Dlo/?		 involves: 129S/Sv * BALB/c * C3H * C57BL/6 J:100072 View
lymphoproliferative syndrome Il6ratm1.1(IL6R)Csk/Il6ratm1.1(IL6R)Csk
Tg(H2-L-IL6)40Csk/0		 involves: 129S6/SvEvTac * C57BL/6 J:207264 View
primary immunodeficiency disease Gt(ROSA)26Sortm1(OVAL/fla,GFP)Vnce/Gt(ROSA)26Sor+
Lyz2tm1(cre)Ifo/Lyz2+		 involves: 129P2/OlaHsd * C57BL/6J J:260047 View
psoriasis Juntm4Wag/Juntm4Wag
Junbtm3Wag/Junbtm3Wag
Tg(Krt1-5-cre/ERT)1Ipc/0		 involves: 129P2/OlaHsd * C57BL/6 * SJL J:116380 View
rheumatoid arthritis H2q/?
Ncf1m1J/Ncf1m1J		 B6.Cg-Ncf1m1J H2q J:92437 View
type 1 diabetes mellitus Casp1tm1Sesh/Casp1tm1Sesh
Casp4del/Casp4del		 NOD.129S2(B6)-Casp1tm1Sesh Casp4del/LtJ J:87250 View
type 1 diabetes mellitus Prkdcscid/Prkdcscid
Tg(INS-HBEGF*L148S*P149T)70Rin/0		 C.BKa-Prkdcscid Tg(INS-HBEGF*L148S*P149T)70Rin J:204420 View
ulcerative colitis Rag2tm1Fwa/Rag2tm1Fwa
Tbx21tm1Glm/Tbx21tm1Glm		 involves: 129S/SvEv * 129S6/SvEvTac J:141481 View

       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      combined T cell and B cell immunodeficiency Il2rgtm1Cgn/Il2rgtm1Cgn involves: 129 * CB20 J:22521 View
combined T cell and B cell immunodeficiency Il2rgtm1Cgn/Y involves: 129 * CB20 J:22521 View
combined T cell and B cell immunodeficiency Il2rgtm1Sug/Y either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129S6/SvEvTac * C57BL/6) J:31167 View
immunodeficiency 24 Ctps1em1Slat/Ctps1em1Slat C57BL/6J-Ctps1em1Slat J:348981 View
Omenn syndrome Rag1tm1Jsek/Rag1tm1Jsek involves: 129S6/SvEvTac J:146912 View
psoriasis Itgb2tm1Bay/Itgb2tm2Bay B6.129S7-Itgb2tm1Bay Itgb2tm2Bay J:84126 View
rheumatoid arthritis Ighmtm1Cgn/Ighmtm1Cgn
Tg(TcraR28,TcrbR28)KRNDim/0		 involves: 129S2/SvPas * C57BL/6 * NOD * SJL J:36815 View
type 1 diabetes mellitus B2mtm1Jae/B2mtm1Jae
Tg(B2m)1Rms/0
Tg(INS-cre)2Rms/0		 involves: 129S2/SvPas * NOD J:83635 View
type 1 diabetes mellitus B2mtm1Unc/B2mtm1Unc NOD.129P2-B2mtm1Unc J:17000 View
type 1 diabetes mellitus B2mtm1Unc/B2mtm1Unc
Ciitatm1Ccum/Ciitatm1Ccum		 NOD.Cg-B2mtm1Unc Ciitatm1Ccum J:107051 View
type 1 diabetes mellitus B2mtm1Unc/B2mtm1Unc
Tg(TcraAI4)1Dvs/0
Tg(TcrbAI4)1Dvs/0		 NOD.Cg-B2mtm1Unc Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs J:93553 View
type 1 diabetes mellitus Casp3tm1Mak/Casp3tm1Mak B6.129P2-Casp3tm1Mak J:97650 View
type 1 diabetes mellitus Cd4tm1Knw/Cd4tm1Knw NOD.Cg-Cd4tm1Knw J:93553 View
type 1 diabetes mellitus Ciitatm1Ccum/Ciitatm1Ccum NOD.129S2(B6)-Ciitatm1Ccum J:106081 View
type 1 diabetes mellitus Ctnna2tm1Mta/Ctnna2tm1Mta Not Specified J:83635 View
type 1 diabetes mellitus Faslpr/Faslpr NOD.MRL(B6)-Faslpr J:64051 View
type 1 diabetes mellitus H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell		 NOD.Cg-H2-Ab1b-tm1Gru Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell J:87013 View
type 1 diabetes mellitus Icam1tm1Jcgr/Icam1tm1Jcgr
Tg(INS-Il10)#Sar/0		 NOD.Cg-Icam1tm1Jcgr Tg(INS-Il10)#Sar J:98583 View
type 1 diabetes mellitus Ighmtm1Cgn/Ighmtm1Cgn NOD.129S2-Ighmtm1Cgn J:37287 View
type 1 diabetes mellitus Ighmtm1Cgn/Ighmtm1Cgn NOD.129S2-Ighmtm1Cgn/DvsJ J:80859 View
type 1 diabetes mellitus Ighmtm1Cgn/Ighmtm1Cgn
Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg		 NOD.Cg-Ighmtm1Cgn Tg(IghelMD4)4Ccg/DvsJ J:80859 View
type 1 diabetes mellitus Ins1tm1Jja/Ins1tm1Jja NOD.129S2-Ins1tm1Jja J:85309 View
type 1 diabetes mellitus Ins1tm1Jja/Ins1tm1Jja
Ins2tm1Jja/Ins2tm1Jja
Tg(Ins2*Y16A)1Ell/0		 NOD.Cg-Ins1tm1Jja Ins2tm1Jja Tg(Ins2*Y16A)1Ell J:98583 View
type 1 diabetes mellitus Ins1tm1Jja/Ins1tm1Jja
Ins2tm1Jja/Ins2tm1Jja
Tg(Ins2*Y16A)3Ell/0		 NOD.Cg-Ins1tm1Jja Ins2tm1Jja Tg(Ins2*Y16A)3Ell J:98583 View
type 1 diabetes mellitus Parp1tm1Hsmm/Parp1tm1Hsmm involves: 129S4/SvJae J:53360 View
type 1 diabetes mellitus Stat4tm1Gru/Stat4tm1Gru NOD.129S2-Stat4tm1Gru J:90600 View
type 1 diabetes mellitus Tg(H2-Ead)5Lt/0 NOD/ShiLt-Tg(H2-Ead)5Lt J:36435 View
type 1 diabetes mellitus Tg(TcrbAI4)1Dvs/0 NOD-Tg(TcrbAI4)1Dvs J:93553 View
type 1 diabetes mellitus Tlr2tm1Aki/Tlr2tm1Aki NOD.129P2-Tlr2tm1Aki J:124334 View
type 1 diabetes mellitus 2 Hk2tm1Laak/Hk2+ involves: 129P2/OlaHsd * BALB/c * DBA/2 J:56644 View
X-linked severe combined immunodeficiency Il2rgtm1Cgn/Il2rgtm1Cgn involves: 129 * CB20 J:22521 View
X-linked severe combined immunodeficiency Il2rgtm1Cgn/Y involves: 129 * CB20 J:22521 View
X-linked severe combined immunodeficiency Il2rgtm1Sug/Y either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129S6/SvEvTac * C57BL/6) J:31167 View