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Phenotypes Associated with This Genotype
Genotype
MGI:8286547
Allelic
Composition
Cabin1em1Dcfaj/Cabin1em2Dcfaj
Genetic
Background
C57BL/6J-Cabin1em1Dcfaj Cabin1em2Dcfaj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cabin1em1Dcfaj mutation (0 available); any Cabin1 mutation (114 available)
Cabin1em2Dcfaj mutation (0 available); any Cabin1 mutation (114 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• normal baseline frequency of B, T and regulatory T cells, and other immune cell populations
• increased morbidity and mortality after infection with lymphocytic choriomeningitis virus clone 13 (LCMV CL13)

mortality/aging
N
• no spontaneous mortality during 1st year
• increased morbidity and mortality after infection with lymphocytic choriomeningitis virus clone 13 (LCMV CL13)

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
multicentric Castleman disease DOID:0111152 J:378928


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/20/2026
MGI 6.24
The Jackson Laboratory