• mice infected with N. brasiliensis exhibit impaired effector cell recruitment and worm expulsion with 4-fold higher worm counts in the small intestine compared to in similarly treated wild-type mice
• nine days after infection with N. brasiliensis, mice exhibit reduced basophil and eosinophil frequencies in the blood and lungs compared to similarly treated wild-type mice
• after infection with N. brasiliensis, total numbers of eosinophils, basophils and CD4+ T cells in the lungs are 5- to 10-fold lower than in similarly treated wild-type mice
• following infection with N. brasiliensis, CD4+ T cells preferentially differentiate towards Th1 and Th17 cells unlike similarly treated wild-type mice whose CD4+ T cells preferentially differentiate towards Th2 cells
• however, IgE levels in mice infected with N. brasiliensis are normal