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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
H2az2
H2A.Z histone variant 2
MGI:1924855
625 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Acvr1tm1Vk/Acvr1tm1.1Vk
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
abnormal aortic arch and aortic arch branch attachment J:90988
abnormal aortic arch morphology J:90988
abnormal brachiocephalic trunk morphology J:90988
abnormal cardiac neural crest cell migration J:90988
abnormal cardiac outflow tract development J:90988
abnormal cartilage morphology J:90453
abnormal frontal bone squamous part morphology J:90453
abnormal malleus morphology J:90453
abnormal mandible morphology J:90453
abnormal mandibular fossa morphology J:90453
abnormal Meckel's cartilage morphology J:90453
abnormal palatal shelf elevation J:90453
abnormal pharyngeal arch artery morphology J:90988
abnormal sixth pharyngeal arch artery morphology J:90988
abnormal suckling behavior J:90453
abnormal third pharyngeal arch artery morphology J:90988
abnormal zygomatic arch morphology J:90453
absent cardiac neural crest cells J:90988
absent mandibular symphysis J:90453
absent retrotympanic process J:90453
absent temporal bone zygomatic process J:90453
absent temporomandibular joint J:90453
absent zygomatic bone J:90453
cleft secondary palate J:90453
conotruncal ridge hypoplasia J:90988
decreased cardiac neural crest cell number J:90988
enlarged heart J:90988
impaired cardiac neural crest cell differentiation J:90988
increased heart right ventricle size J:90988
large anterior fontanelle J:90453
lethality throughout fetal growth and development, incomplete penetrance J:90453, J:90988
mandible hypoplasia J:90453
neonatal lethality, complete penetrance J:90988
persistent truncus arteriosis J:90988
retroesophageal right subclavian artery J:90988
short malleus manubrium J:90453
short mandible J:90453
shortened head J:90453
small mandibular coronoid process J:90453
small temporal bone squamous part J:90453
ventricular septal defect J:90988
Adam22tm1.1Mejr/Adam22tm1.1Mejr
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
abnormal myelination J:158973
abnormal neuron morphology J:158973
Arid1atm1.1Mag/Arid1a+
H2az2Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * CBA/J
abnormal body composition J:231470
abnormal palatine bone morphology J:231470
enophthalmos J:231470
lowered ear position J:231470
short premaxilla J:231470
short snout J:231470
small temporal bone squamous part J:231470
Arid1atm1.1Mag/Arid1atm1.1Mag
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
abnormal cardiac neural crest cell migration J:231470
abnormal cardiac outflow tract development J:231470
abnormal conotruncus septation J:231470
abnormal neural crest cell migration J:231470
Arid1atm1.1Mag/Arid1atm1.1Mag
H2az2Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * CBA/J
abnormal aortic valve morphology J:231470
abnormal blood vessel morphology J:231470
abnormal cardiac neural crest cell migration J:231470
abnormal cardiac neural crest cell morphology J:231470
abnormal cardiac outflow tract development J:231470
abnormal cranium morphology J:231470
abnormal eye distance/ position J:231470
abnormal first pharyngeal arch morphology J:231470
abnormal fourth pharyngeal arch artery morphology J:231470
abnormal interventricular septum morphology J:231470
abnormal neurocranium morphology J:231470
abnormal pulmonary valve morphology J:231470
abnormal sixth pharyngeal arch artery morphology J:231470
abnormal third pharyngeal arch artery morphology J:231470
absent fetal ductus arteriosus J:231470
lethality throughout fetal growth and development, incomplete penetrance J:231470
lowered ear position J:231470
microcephaly J:231470
persistent truncus arteriosis J:231470
short snout J:231470
Bdnftm1Krj/Bdnftm1Lfr
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S2/SvPas * C57BL/6 * CBA
abnormal substantia nigra morphology J:99291
abnormal substantia nigra pars compacta morphology J:99291
impaired coordination J:99291
limb grasping J:99291
Bhlhe22tm2.1Meg/Bhlhe22tm2.1Meg
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129/Sv * C57BL/6J * CBA/J
abnormal chemical nociception J:158273
excessive scratching J:158273
skin lesions J:158273
Bmp2tm1Jfm/Bmp2+
Bmp4tm1Jfm/Bmp4+
Bmp7tm1Jfm/Bmp7tm1Jfm
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
absent alisphenoid bone J:181229
cleft palate J:181229
decreased tympanic ring size J:181229
small temporal bone squamous part J:181229
Bmp2tm1Jfm/Bmp2+
Bmp4tm1Jfm/Bmp4tm1Jfm
Bmp7tm1Jfm/Bmp7+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
cleft palate J:181229
decreased tympanic ring size J:181229
small alisphenoid bone J:181229
small nasal bone J:181229
small temporal bone squamous part J:181229
small zygomatic bone J:181229
Bmp2tm1Jfm/Bmp2+
Bmp4tm1Jfm/Bmp4tm1Jfm
Bmp7tm1Jfm/Bmp7tm1Jfm
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
abnormal tympanic ring morphology J:181229
cleft palate J:181229
small interparietal bone J:181229
small nasal bone J:181229
small temporal bone squamous part J:181229
small zygomatic bone J:181229
Bmp2tm1Jfm/Bmp2+
Bmp4tm1Jfm/Bmp4tm1Jfm
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
small interparietal bone J:181229
Bmp2tm1Jfm/Bmp2tm1Jfm
Bmp4tm1Jfm/Bmp4+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
absent alisphenoid bone J:181229
absent mandibular coronoid process J:181229
absent zygomatic bone J:181229
cleft palate J:181229
small nasal bone J:181229
Bmp2tm1Jfm/Bmp2tm1Jfm
Bmp4tm1Jfm/Bmp4+
Bmp7tm1Jfm/Bmp7+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
absent alisphenoid bone J:181229
absent mandibular coronoid process J:181229
absent zygomatic bone J:181229
cleft palate J:181229
small nasal bone J:181229
Bmp2tm1Jfm/Bmp2tm1Jfm
Bmp4tm1Jfm/Bmp4+
Bmp7tm1Jfm/Bmp7tm1Jfm
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
abnormal temporal bone squamous part morphology J:181229
abnormal tympanic ring morphology J:181229
absent alisphenoid bone J:181229
absent mandibular coronoid process J:181229
absent zygomatic bone J:181229
cleft palate J:181229
small nasal bone J:181229
Bmp2tm1Jfm/Bmp2tm1Jfm
Bmp4tm1Jfm/Bmp4tm1Jfm
Bmp7tm1Jfm/Bmp7+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
abnormal interparietal bone morphology J:181229
abnormal mandibular angle morphology J:181229
abnormal mandibular condyloid process morphology J:181229
abnormal nasal bone morphology J:181229
absent alisphenoid bone J:181229
absent mandibular coronoid process J:181229
absent maxilla J:181229
absent temporal bone squamous part J:181229
absent tympanic ring J:181229
absent zygomatic bone J:181229
cleft palate J:181229
Bmp2tm1Jfm/Bmp2tm1Jfm
Bmp4tm1Jfm/Bmp4tm1Jfm
Bmp7tm1Jfm/Bmp7tm1Jfm
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
abnormal craniofacial bone morphology J:181229
abnormal interparietal bone morphology J:181229
abnormal mandible morphology J:181229
abnormal nasal bone morphology J:181229
absent alisphenoid bone J:181229
absent mandibular angle J:181229
absent mandibular condyloid process J:181229
absent mandibular coronoid process J:181229
absent maxilla J:181229
absent temporal bone squamous part J:181229
absent tympanic ring J:181229
absent zygomatic bone J:181229
cleft palate J:181229
large anterior fontanelle J:181229
Bmp2tm1Jfm/Bmp2tm1Jfm
Bmp4tm1Jfm/Bmp4tm1Jfm
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
abnormal craniofacial bone morphology J:181229
abnormal interparietal bone morphology J:181229
abnormal mandible morphology J:181229
abnormal mandibular angle morphology J:181229
abnormal mandibular condyloid process morphology J:181229
abnormal nasal bone morphology J:181229
abnormal temporal bone squamous part morphology J:181229
absent alisphenoid bone J:181229
absent mandibular coronoid process J:181229
absent maxilla J:181229
absent tympanic ring J:181229
absent zygomatic bone J:181229
cleft palate J:181229
large anterior fontanelle J:181229
Bmp4tm1Jfm/Bmp4tm1Jfm
Bmp7tm1Jfm/Bmp7tm1Jfm
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
abnormal mandible morphology J:181229
cleft palate J:181229
decreased tympanic ring size J:181229
large anterior fontanelle J:181229
small temporal bone squamous part J:181229
Bmp4tm1Jfm/Bmp4tm1Jfm
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
abnormal mandible morphology J:181229
impaired osteoblast differentiation J:181229
large anterior fontanelle J:181229
small interparietal bone J:181229
Bmp4tm2(tetO-Bmp4,lacZ)Jfm/Bmp4+
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129/Sv * C57BL/6J * CBA/J
abnormal craniofacial bone morphology J:181229
abnormal eye distance/ position J:181229
abnormal frontal bone morphology J:181229
abnormal mandible morphology J:181229
abnormal maxilla morphology J:181229
abnormal nasal capsule morphology J:181229
absent frontal bone J:181229
absent nasal bone J:181229
cleft palate J:181229
enlarged Meckel's cartilage J:181229
round head J:181229
short face J:181229
short mandible J:181229
short maxilla J:181229
small frontal bone J:181229
small mandibular coronoid process J:181229
small nasal bone J:181229
Bmp7tm1.1Dgra/Bmp7tm1.1Dgra
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac * CBA/J
abnormal basicranium angle J:302309
abnormal basisphenoid bone morphology J:302309
abnormal face development J:302309
abnormal nasal bone morphology J:302309
abnormal neurocranium morphology J:302309
abnormal respiration J:302309
abnormal snout morphology J:302309
abnormal turbinate morphology J:302309
apnea J:302309
decreased body temperature J:302309
decreased oxygen consumption J:302309
decreased pulmonary respiratory rate J:302309
deviated nasal septum J:302309
frontal bossing J:302309
impaired exercise endurance J:302309
increased circulating hydroxyproline level J:302309
midface hypoplasia J:302309
nasal obstruction J:302309
premature death J:302309
short basicranium J:302309
short nasal bone J:302309
Bmpr2tm1.1Enl/Bmpr2tm1.2Enl
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJae * C57BL/6J * CBA/J
abnormal ophthalmic nerve morphology J:206541
normal nervous system phenotype J:206541
Braftm1Wds/Braftm1Wds
Raf1tm2Bacc/Raf1tm2Bacc
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129P2/OlaHsd * C57BL/6J * CBA/J
abnormal conotruncus morphology J:144862
abnormal thyroid gland morphology J:144862
double outlet right ventricle J:144862
normal growth/size/body region phenotype J:144862
normal hearing/vestibular/ear phenotype J:144862
lethality throughout fetal growth and development, complete penetrance J:144862
mandible hypoplasia J:144862
persistent truncus arteriosis J:144862
short maxilla J:144862
small thymus J:144862
small thyroid gland J:144862
ventricular septal defect J:144862
Cbfbtm2.1Ddg/Cbfbtm2.1Ddg
H2az2Tg(Wnt1-cre)11Rth/?
involves: 129S6/SvEvTac * C57BL/6J * CBA/J
abnormal craniofacial development J:226826
perinatal lethality J:226826
Cbfbtm2.1Ddg/Cbfbtm2.1Ddg
Mapttm2Arbr/?
H2az2Tg(Wnt1-cre)11Rth/?
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * CBA/J
abnormal axon morphology J:226826
abnormal craniofacial development J:226826
abnormal nociceptor morphology J:226826
abnormal sensory neuron innervation pattern J:226826
perinatal lethality J:226826
Chd7Gt(XK403)Byg/Chd7+
H2az2Tg(Wnt1-cre)11Rth/0
either: (involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA/J) or (involves: 129P2/OlaHsd * C57BL/6J * CBA/J * CD-1)
abnormal fourth pharyngeal arch artery morphology J:154590
Cited2tm1Bha/Cited2tm2Bha
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129 * C57BL/6 * CBA * SJL
abnormal glossopharyngeal ganglion morphology J:137951
abnormal vagus ganglion morphology J:137951
decreased survivor rate J:137951
exencephaly J:137951
postnatal lethality, incomplete penetrance J:137951
small geniculate ganglion J:137951
small trigeminal ganglion J:137951
small vestibular ganglion J:137951
Col1a1tm1(tetO-EWSR1/ATF1)Yasu/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Tg(CAG-cat,-lacZ)11Miya/0
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJae * C57BL/6 * CBA/J * DBA/2
increased sarcoma incidence J:194505
Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129X1/SvJ * C57BL/6 * CBA
abnormal muscle development J:124278
Ctnnb1tm2Kem/Ctnnb1tm2.1Kem
Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * CBA/J
abnormal brain morphology J:187739
abnormal craniofacial morphology J:187739
prenatal lethality, complete penetrance J:187739
Ctnnb1tm2Kem/Ctnnb1tm2.1Kem
Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * CBA/J
neonatal lethality, complete penetrance J:187739
Ctnnb1tm2Kem/Ctnnb1tm2.1Kem
H2az2Tg(Wnt1-cre)11Rth/?
involves: 129/Sv * C57BL/6 * CBA
abnormal brain development J:67966
abnormal brain morphology J:67966
abnormal cranial nerve morphology J:67966
abnormal dorsal root ganglion morphology J:67966
abnormal facial nerve morphology J:67966
abnormal glossopharyngeal nerve morphology J:67966
abnormal hindbrain morphology J:67966
abnormal hypoglossal nerve morphology J:67966
abnormal neural tube morphology J:67966
abnormal telencephalon morphology J:67966
abnormal trigeminal V mesencephalic nucleus morphology J:67966
abnormal vagus nerve morphology J:67966
absent cerebellum J:67966
absent choroid plexus J:67966
absent craniofacial bones J:67966
absent metencephalon J:67966
absent midbrain J:67966
absent midbrain-hindbrain boundary J:67966
absent oculomotor nerve J:67966
prenatal lethality, complete penetrance J:67966
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129 * C57BL/6 * CBA/J
absent hindbrain J:178971
absent mandible J:178971
absent maxilla J:178971
absent midbrain J:178971
absent midbrain-hindbrain boundary J:178971
small pharyngeal arch J:178971
Ctnnb1tm2Kem/Ctnnb1tm2Kem
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129 * C57BL/6 * CBA/J
abnormal craniofacial morphology J:178971
abnormal neural tube morphology J:178971
abnormal telencephalon development J:178971
absent midbrain-hindbrain boundary J:178971
premature neuronal precursor differentiation J:178971
Ctnnb1tm2Kem/Ctnnb1tm3Kba
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129 * C57BL/6 * CBA/J
abnormal cerebellum development J:178971
abnormal craniofacial bone morphology J:178971
absent midbrain-hindbrain boundary J:178971
Ctnnb1tm2Kem/Ctnnb1tm3Kba
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129 * C57BL/6 * CBA/J
abnormal craniofacial morphology J:178971
abnormal midbrain morphology J:178971
abnormal neuron differentiation J:178971
normal embryo phenotype J:178971
Dicer1tm1Bdh/Dicer1+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129 * C57BL/6 * CBA/J
abnormal thymus development J:166758
Dicer1tm1Bdh/Dicer1tm1Bdh
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129 * C57BL/6 * CBA/J
abnormal aortic arch development J:166758
abnormal cartilage morphology J:166758
abnormal craniofacial morphology J:166758
abnormal dorsal root ganglion morphology J:166758
abnormal first pharyngeal arch morphology J:166758
abnormal sympathetic ganglion morphology J:166758
athymia J:166758
lethality throughout fetal growth and development, complete penetrance J:166758
persistent truncus arteriosis J:166758
ventricular septal defect J:166758
Dph1tm1.1Cmch/Dph1tm1.1Cmch
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J
small nasal bone J:214744
Dph1tm1.1Cmch/Dph1tm1.1Cmch
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J
cleft palate J:214744
decreased cranium length J:214744
postnatal lethality, incomplete penetrance J:214744
round face J:214744
short mandible J:214744
short Meckel's cartilage J:214744
short nasal bone J:214744
Dph1tm2Bhr/Dph1+
Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S/SvEv * 129S4/SvJae * C57BL/6J * CBA/J
acephaly J:214744
Dph1tm2Bhr/Dph1tm2Bhr
Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S/SvEv * 129S4/SvJae * C57BL/6J * CBA/J
normal growth/size/body region phenotype J:214744
Dvl3tm1Awb/Dvl3tm1Awb
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S/Sv * Black Swiss * C57BL/6J * CBA/J
normal nervous system phenotype J:142392
Ednratm2Ywa/Ednratm2Ywa
H2az2Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * CBA/J
abnormal craniofacial bone morphology J:149166
abnormal craniofacial morphology J:149166
abnormal incisor morphology J:149166
abnormal incus morphology J:149166
abnormal malleus morphology J:149166
abnormal mandible morphology J:149166
abnormal mouth floor morphology J:149166
abnormal stapes morphology J:149166
absent incus J:149166
absent malleus J:149166
absent Meckel's cartilage J:149166
facial cleft J:149166
short mandible J:149166
tongue hypoplasia J:149166
Ednrbtm1Nrd/Ednrbtm1Nrd
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA/J
abnormal enteric neural crest cell migration J:140320
aganglionic megacolon J:140320
distended abdomen J:140320
premature death J:140320
slow postnatal weight gain J:140320
white spotting J:140320
Ednrbtm1Nrd/Ednrbtm1Nrd
Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J
abnormal mature B cell number J:233811
abnormal Peyer's patch morphology J:233811
abnormal spleen morphology J:233811
abnormal splenic cell ratio J:233811
decreased B cell number J:233811
decreased germinal center B cell number J:233811
decreased IgA level J:233811
decreased marginal zone B cell number J:233811
decreased spleen red pulp amount J:233811
decreased spleen weight J:233811
decreased spleen white pulp amount J:233811
large intestinal inflammation J:233811
small Peyer's patches J:233811
small spleen J:233811
Efnb1tm1Sor/Efnb1+
H2az2Tg(Wnt1-cre)11Rth/?
involves: 129S4/SvJaeSor * C57BL/6 * CBA
abnormal tympanic ring morphology J:89008
cleft palate J:89008
failure of palatal shelf elevation J:89008
Elp1tm1c(KOMP)Wtsi/Elp1tm1c(KOMP)Wtsi
H2az2Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * C57BL/6N * CBA/J
abnormal dorsal root ganglion morphology J:202989
abnormal facial morphology J:202989
abnormal nervous system physiology J:202989
abnormal neuron differentiation J:202989
abnormal sensory neuron innervation pattern J:202989
abnormal submandibular gland morphology J:202989
abnormal superior cervical ganglion morphology J:202989
decreased fetal size J:202989
decreased neuron number J:202989
decreased sensory neuron number J:202989
increased neuron apoptosis J:202989
increased neuron number J:202989
mandibular retrognathia J:202989
neonatal lethality, complete penetrance J:202989
Ext1tm1Yama/Ext1+
H2az2Tg(Wnt1-cre)11Rth/0
Tgfb2tm1Doe/Tgfb2+
B6.Cg-Tgfb2tm1Doe H2az2Tg(Wnt1-cre)11Rth Ext1tm1Yama
abnormal aqueous drainage system morphology J:152572
abnormal canal of Schlemm morphology J:152572
abnormal trabecular meshwork morphology J:152572
normal mortality/aging J:152572
ocular hypertension J:152572
Ext1tm1Yama/Ext1tm1Yama
H2az2Tg(Wnt1-cre)11Rth/0
B6.Cg-H2az2Tg(Wnt1-cre)11Rth Ext1tm1Yama
abnormal corneal stroma morphology J:152572
abnormal craniofacial morphology J:152572
abnormal ear morphology J:152572
abnormal eye morphology J:152572
abnormal iridocorneal angle J:152572
absent eyelids J:152572
absent hard palate J:152572
ciliary body coloboma J:152572
cleft secondary palate J:152572
decreased cornea thickness J:152572
decreased cranial neural crest cell proliferation J:152572
decreased eye anterior chamber depth J:152572
iris coloboma J:152572
neonatal lethality, complete penetrance J:152572
Fgf15tm1Sms/Fgf15tm1Sms
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * CBA
abnormal cardiac neural crest cell migration J:97317
abnormal cardiac outflow tract development J:97317
decreased cardiac neural crest cell number J:97317
Fgfr1tm1Jpa/Fgfr1tm1.1Jpa
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * ICR
abnormal craniofacial bone morphology J:81179
cleft palate J:81179
normal craniofacial phenotype J:81179
Fgfr1tm1Jpa/Fgfr1tm1Jpa
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
abnormal cerebellum development J:83004
abnormal cerebellum vermis morphology J:83004
absent inferior colliculus J:83004
neonatal lethality J:83004
Fgfr1tm1Jpa/Fgfr1tm1Jpa
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * ICR
abnormal hyoid bone lesser horn morphology J:81179
cleft palate J:81179
normal craniofacial phenotype J:81179
Fgfr1tm2Jrt/Fgfr1tm2Jrt
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * ICR
abnormal alisphenoid bone morphology J:81179
abnormal incus morphology J:81179
abnormal malleus morphology J:81179
abnormal middle ear ossicle morphology J:81179
abnormal pterygoid bone morphology J:81179
abnormal second pharyngeal arch morphology J:81179
abnormal temporal bone squamous part morphology J:81179
normal craniofacial phenotype J:81179
decreased tympanic ring size J:81179
small gonial bone J:81179
Fgfr1tm5.1Sor/Fgfr1tm5.1Sor
H2az2Tg(Wnt1-cre)11Rth/0
129S4.Cg-Fgfr1tm5.1Sor H2az2Tg(Wnt1-cre)11Rth
midline facial cleft J:226497
Fgfr1tm5.1Sor/Fgfr1tm9.1Sor
H2az2Tg(Wnt1-cre)11Rth/0
129S4.Cg-Fgfr1tm5.1Sor Fgfr1tm9.1Sor H2az2Tg(Wnt1-cre)11Rth
cleft palate J:226497
Fgfr1tm5.1Sor/Fgfr1tm10.1Sor
H2az2Tg(Wnt1-cre)11Rth/0
129S4.Cg-Fgfr1tm5.1Sor Fgfr1tm10.1Sor H2az2Tg(Wnt1-cre)11Rth
cleft palate J:226497
Fgfr1tm5.1Sor/Fgfr1tm10.1Sor
Stat3tm2Aki/Stat3tm2Aki
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129P2/OlaHsd * 129S4/SvJaeSor
normal craniofacial phenotype J:226497
Fgfr2tm1Dor/Fgfr2tm1Dor
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129X1/SvJ * C57BL/6J * CBA/J
normal vision/eye phenotype J:130571
Fkbp1atm1.1Shou/Fkbp1atm1Zuk
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S7/SvEvBrd * C57BL/6J * CBA/J
normal cardiovascular system phenotype J:195489
premature death J:195489
Flnatm1.1Caw/Y
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJae * C57BL/6 * CBA
abnormal atrioventricular cushion morphology J:118252
abnormal blood vessel morphology J:118252
abnormal brain size J:118252
abnormal cardiac outflow tract development J:118252
abnormal vascular endothelial cell morphology J:118252
abnormal vascular endothelial cell physiology J:118252
normal behavior/neurological phenotype J:118252
cyanosis J:118252
interrupted aortic arch J:118252
neonatal lethality, complete penetrance J:118252
persistent truncus arteriosis J:118252
Foxd3tm2Lby/Foxd3tm3Lby
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S6/SvEvTac * C57BL/6 * CBA
abnormal cardiac neural crest cell migration J:134482
abnormal common carotid artery morphology J:134482
abnormal cranium morphology J:134482
abnormal dorsal spinal root morphology J:134482
abnormal enteric nervous system morphology J:134482
abnormal enteric neural crest cell migration J:134482
abnormal heart development J:134482
abnormal spinal nerve morphology J:134482
absent frontal bone J:134482
absent nasal capsule J:134482
cleft palate J:134482
eyelids open at birth J:134482
increased apoptosis J:134482
increased hindbrain apoptosis J:134482
mandibular hyperostosis J:134482
midline facial cleft J:134482
perinatal lethality, complete penetrance J:134482
persistent truncus arteriosis J:134482
respiratory failure J:134482
short mandible J:134482
short maxilla J:134482
short premaxilla J:134482
small basioccipital bone J:134482
small dorsal root ganglion J:134482
small interparietal bone J:134482
small parietal bone J:134482
small pharyngeal arch J:134482
Gata6tm2Msp/Gata6tm2Msp
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
abnormal cardiovascular system morphology J:107814
aortic arch hypoplasia J:107814
double outlet right ventricle J:107814
interrupted aortic arch J:107814
perimembraneous ventricular septal defect J:107814
perinatal lethality, complete penetrance J:107814
persistent truncus arteriosis J:107814
retroesophageal right subclavian artery J:107814
Gja1tm1Gfi/Gja1tm1Gfi
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129/Sv * C57BL/6J * CBA/J * FVB/N
abnormal ascending aorta and coronary artery attachment J:108525
Gja1tm1Kwi/Gja1tm1Kwi
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129P2/OlaHsd * C57BL/6 * CBA
no abnormal phenotype detected J:110142
Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/0
either: (involves: 129S/SvEv * C57BL/6 * CBA) or (involves: 129S/SvEv * C57BL/6 * CBA * CD-1)
absent midbrain-hindbrain boundary J:103417
decreased midbrain size J:103417
open neural tube J:103417
Gt(ROSA)26Sortm1(PDGFRA*)Hsc/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129/Sv * C57BL/6 * CBA
abnormal interfrontal bone morphology J:145520
abnormal intramembranous bone ossification J:145520
premature coronal suture closure J:145520
premature intramembranous bone ossification J:145520
premature metopic suture closure J:145520
short snout J:145520
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129X1/SvJ * C57BL/6J * CBA/J
abnormal cardiac outflow tract development J:135134
embryonic lethality during organogenesis, incomplete penetrance J:135134
increased cardiac neural crest cell number J:135134
persistent truncus arteriosis J:135134
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/?
H2az2Tg(Wnt1-cre)11Rth/?
involves: 129X1/SvJ * C57BL/6J * CBA/J
abnormal face development J:89445
abnormal head development J:89445
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Mef2ctm1Eno/Mef2ctm1Jjs
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJaeSor * 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6J * CBA/J
normal embryo phenotype J:122483
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Msx2tm1Rilm/Msx2tm1Rilm
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJae * C57BL/6J * CBA/J
fused cornea and lens J:184697
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
HhatTg(TFAP2A-cre)1Will/HhatTg(TFAP2A-cre)1Will
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * CBA
abnormal cranial ganglia morphology J:190013
abnormal trigeminal ganglion morphology J:190013
small trigeminal ganglion J:190013
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Isl1tm2Sev/Isl1tm2Sev
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
abnormal dorsal root ganglion morphology J:141110
abnormal sensory neuron innervation pattern J:141110
abnormal trigeminal ganglion morphology J:141110
decreased chemical nociceptive threshold J:141110
dorsal root ganglion hypoplasia J:141110
neonatal lethality, complete penetrance J:141110
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Ptpn11tm1.1Rbns/Ptpn11tm1.1Rbns
H2az2Tg(Wnt1-cre)11Rth/0
B6.Cg-Ptpn11tm1.1Rbns Gt(ROSA)26Sortm1Sor H2az2Tg(Wnt1-cre)11Rth
decreased cardiac neural crest cell number J:150835
impaired cranial neural crest cell differentiation J:150835
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Resttm1.1Yasu/Resttm1.1Yasu
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJae * C57BL/6 * C57BL/6J * CBA/J
abnormal melanoblast morphology J:230341
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Sox11tm2.1Weg/Sox11tm2.1Weg
Sox4tm1Vlf/Sox4tm1Vlf
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129 * C57BL/6 * C57BL/6J * CBA/J
abnormal pharyngeal arch development J:175338
Gt(ROSA)26Sortm1Sor/0
H2az2Tg(Wnt1-cre)11Rth/0
Pgap2clpex/Pgap2clpex
involves: 129S4/SvJaeSor * A/J * C57BL/6J * CBA/J
abnormal lateral nasal prominence morphology J:277316
abnormal medial nasal prominence morphology J:277316
Gt(ROSA)26Sortm1Sor/?
Myctm2Fwa/Myctm2Fwa
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * CBA
abnormal coronal suture morphology J:121871
abnormal frontal bone morphology J:121871
abnormal malleus morphology J:121871
short nasal bone J:121871
small malleus J:121871
small malleus manubrium J:121871
Gt(ROSA)26Sortm2(DTA)Riet/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129P2/OlaHsd * C57BL/6J * CBA/J
abnormal facial nerve morphology J:157532
Gt(ROSA)26Sortm2(Pax3)Joe/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
cleft palate J:137730
Gt(ROSA)26Sortm2(Pax3)Joe/Gt(ROSA)26Sortm2(Pax3)Joe
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
abnormal craniofacial morphology J:137730
abnormal eyelid morphology J:137730
abnormal palate morphology J:137730
Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/?
involves: C57BL/6J * CBA/J
embryonic lethality, complete penetrance J:194308
Gt(ROSA)26Sortm5(Wnt5a)Flng/?
H2az2Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * CBA/J
abnormal craniofacial morphology J:208766
embryonic lethality J:208766
Gt(ROSA)26Sortm7(SMO*/YFP)Amc/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJae *129X1/SvJ * C57BL/6 * CBA * Swiss Webster
abnormal brain development J:165962
abnormal frontonasal prominence morphology J:165962
H2az1tm1.1Hko/H2az1tm1.1Hko
H2az2tm1.1Hko/H2az2tm1.1Hko
Tg(Vil1-cre)20Syr/0
B6.Cg-H2az1tm1.1Hko H2az2tm1.1Hko Tg(Vil1-cre)20Syr
abnormal crypts of Lieberkuhn morphology J:276456
decreased body weight J:276456
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Lrp2tm1Tew/Lrp2tm1Tew
involves: C57BL/6J * CBA/J
normal vision/eye phenotype J:238249
H2az2Tg(Wnt1-cre)11Rth/0
Pigatm1Tak/Y
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J
abnormal craniofacial bone morphology J:277316
cleft palate J:277316
cleft upper lip J:277316
H2az2Tg(Wnt1-cre)11Rth/?
Tg(CAG-Lhx,-EGFP)1Eno/?
involves: C3H * C57BL/6
failure of intramembranous bone ossification J:150709
frontal bone foramen J:150709
intracranial hemorrhage J:150709
neonatal lethality, complete penetrance J:150709
H2az2Tg(Wnt1-cre)11Rth/0
Tg(Wnt1-GAL4)11Rth/0
involves: C57BL/6J * CBA/J * Swiss albino
abnormal anxiety-related response J:192250
abnormal behavior J:192250
abnormal midbrain development J:192250
abnormal nest building behavior J:192250
abnormal social investigation J:192250
abnormal spatial learning J:192250
hyperactivity J:192250
H2az2Tg(Wnt1-cre)11Rth/0
Wnt5atm1Amc/Wnt5atm1.1Krvl
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * CBA/J
abnormal axon extension J:196291
abnormal craniofacial morphology J:196291
abnormal sympathetic neuron innervation pattern J:196291
increased neuron apoptosis J:196291
neonatal lethality, complete penetrance J:196291
Hand2tm1.1Majh/Hand2tm1.1Majh
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/SvImJ * C57BL/6 * CBA * DBA/2
abnormal craniofacial bone morphology J:137726
abnormal enteric ganglia morphology J:138032
abnormal enteric nervous system morphology J:138032
abnormal enteric neuron morphology J:138032
abnormal heart development J:137726
abnormal neuron differentiation J:137726
abnormal sympathetic ganglion morphology J:137726
decreased embryo size J:137726
embryonic lethality during organogenesis, complete penetrance J:137726
normal nervous system phenotype J:137726
short mandible J:137726
Hand2tm1Cse/Hand2+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * C57BL/6J * CBA/J
aberrant origin of the right subclavian artery J:155265
abnormal cell cycle J:155265
abnormal fetal cardiomyocyte proliferation J:155265
abnormal myocardial trabeculae morphology J:155265
abnormal thymus development J:155265
normal embryo phenotype J:155265
heart right ventricle hypertrophy J:155265
interrupted aortic arch J:155265
lethality throughout fetal growth and development, complete penetrance J:155265
perimembraneous ventricular septal defect J:155265
pulmonary artery stenosis J:155265
retroesophageal right subclavian artery J:155265
Hand2tm1Cse/Hand2tm1Cse
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6 * CBA
normal craniofacial phenotype J:149232
Hand2tm1Cse/Hand2tm1Dsr
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6 * CBA
abnormal adrenergic neuron morphology J:122604
abnormal blood circulation J:122604
abnormal enzyme/coenzyme level J:122604
embryonic lethality during organogenesis, complete penetrance J:122604
normal nervous system phenotype J:122604
visceral vascular congestion J:122604
Hdac1tm1.1Eno/Hdac1tm1.1Eno
H2az2Tg(Wnt1-cre)11Rth/?
involves: 129 * C57BL/6 * CBA
no abnormal phenotype detected J:150709
Hdac2tm1.1Eno/Hdac2tm1.1Eno
H2az2Tg(Wnt1-cre)11Rth/?
involves: 129 * C57BL/6 * CBA
no abnormal phenotype detected J:150709
Hdac8tm1.1Eno/Y
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129 * C57BL/6 * CBA * CD-1
failure of intramembranous bone ossification J:150709
frontal bone foramen J:150709
intracranial hemorrhage J:150709
neonatal lethality, incomplete penetrance J:150709
Hic2Gt(E225A08)1.1Wrst/Hic2Gt(E225A08)1.1Wrst
H2az2Tg(Wnt1-cre)11Rth/?
involves: 129P2/OlaHsd * C57BL/6J * CBA/J
normal mortality/aging J:225226
Hmx1tm1.1Arte/Hmx1tm1.1Arte
H2az2Tg(Wnt1-cre)11Rth/0
involves: BALB/c * C57BL/6J * CBA/J
abnormal innervation J:198834
abnormal neuron differentiation J:198834
Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129/Sv * C57BL/6J * CBA/J
abnormal craniofacial bone morphology J:102845
abnormal gonial bone morphology J:102845
abnormal hyoid bone morphology J:102845
abnormal incus morphology J:102845
abnormal malleus morphology J:102845
abnormal Meckel's cartilage morphology J:102845
abnormal tympanic ring morphology J:102845
absent outer ear J:102845
absent stapes J:102845
absent styloid process J:102845
Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S2/SvPas * C57BL/6 * SJL
abnormal cochlear VIII nucleus morphology J:197162
lethality throughout fetal growth and development J:197162
Hoxa3tm1Mrc/Hoxa3tm3.1Nrm
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S7/SvEvBrd * C57BL/6J * CBA/J
ectopic parathyroid gland J:161296
ectopic thymus J:161296
Hoxa3tm2Nrm/Hoxa3tm3.1Nrm
H2az2Tg(Wnt1-cre)11Rth/0
involves: C3H * C57BL/6 * CBA/J
ectopic parathyroid gland J:161296
ectopic thymus J:161296
Hoxb1tm5Mrc/Hoxb1tm7Mrc
H2az2Tg(Wnt1-cre)11Rth/0
Not Specified
abnormal blinking J:91364
abnormal facial nerve morphology J:91364
abnormal reflex J:91364
abnormal vibrissae reflex J:91364
decreased motor neuron number J:91364
paralysis J:91364
Hprttm2(Pgk1-Pac/TK)Brd/Hprt+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S7/SvEvBrd * C57BL/6 * CBA
abnormal aortic arch morphology J:130481
abnormal aortic valve morphology J:130481
abnormal cardiac outflow tract development J:130481
abnormal cardiovascular development J:130481
abnormal craniofacial morphology J:130481
abnormal heart morphology J:130481
abnormal heart right ventricle morphology J:130481
abnormal heart valve morphology J:130481
abnormal mitral valve morphology J:130481
abnormal neural crest cell morphology J:130481
abnormal pharyngeal arch mesenchyme morphology J:130481
congestive heart failure J:130481
decreased embryo size J:130481
double outlet right ventricle J:130481
edema J:130481
embryonic lethality during organogenesis, incomplete penetrance J:130481
enlarged heart J:130481
heart right ventricle outflow tract stenosis J:130481
interrupted aortic arch J:130481
overriding aortic valve J:130481
pericardial effusion J:130481
persistent truncus arteriosis J:130481
pulmonary valve stenosis J:130481
retroesophageal right subclavian artery J:130481
right aortic arch J:130481
transposition of great arteries J:130481
ventricular septal defect J:130481
Hprttm2(Pgk1-Pac/TK)Brd/Y
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S7/SvEvBrd * C57BL/6 * CBA
abnormal aortic arch morphology J:130481
abnormal aortic valve morphology J:130481
abnormal cardiac outflow tract development J:130481
abnormal cardiovascular development J:130481
abnormal craniofacial morphology J:130481
abnormal heart morphology J:130481
abnormal heart right ventricle morphology J:130481
abnormal heart valve morphology J:130481
abnormal mitral valve morphology J:130481
abnormal neural crest cell morphology J:130481
abnormal pharyngeal arch mesenchyme morphology J:130481
congestive heart failure J:130481
decreased embryo size J:130481
double outlet right ventricle J:130481
edema J:130481
embryonic lethality during organogenesis, incomplete penetrance J:130481
enlarged heart J:130481
heart right ventricle outflow tract stenosis J:130481
interrupted aortic arch J:130481
overriding aortic valve J:130481
pericardial effusion J:130481
persistent truncus arteriosis J:130481
pulmonary valve stenosis J:130481
retroesophageal right subclavian artery J:130481
right aortic arch J:130481
transposition of great arteries J:130481
ventricular septal defect J:130481
Hs2st1tm1.1Je/Hs2st1tm1.1Je
Hs6st1tm1Wvc/Hs6st1tm1Wvc
Hs6st2tm1Lex/Hs6st2tm1Lex
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129 * C57BL/6J * CBA/J
normal endocrine/exocrine gland phenotype J:185652
Irx3tm3Hui/Irx3tm3Hui
Irx5tm3Hui/Irx5tm3Hui
H2az2Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * CBA/J
normal cardiovascular system phenotype J:189007
Jag1tm2Grid/Jag1tm2Grid
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * C57BL/6 * CBA
abnormal blood vessel morphology J:181120
abnormal eating behavior J:181120
abnormal palate morphology J:181120
abnormal primary palate development J:181120
decreased body size J:181120
decreased palatal length J:181120
malocclusion J:181120
midface hypoplasia J:181120
premature death J:181120
short maxilla J:181120
Kif3atm2Gsn/Kif3atm2Gsn
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J
abnormal basisphenoid bone morphology J:158523
abnormal cranial neural crest cell morphology J:158523
abnormal craniofacial bone morphology J:158523
abnormal craniofacial development J:158523
abnormal cranium morphology J:158523
abnormal frontal bone morphology J:158523
abnormal maxilla morphology J:158523
abnormal nasal bone morphology J:158523
abnormal nasal septum morphology J:158523
abnormal palatine bone morphology J:158523
abnormal premaxilla morphology J:158523
absent corpus callosum J:158523
absent mandibular condyloid process J:158523
absent mandibular ramus J:158523
anterior cranium occultum J:158523
broad frontonasal prominence J:158523
cleft secondary palate J:158523
increased cranial neural crest cell proliferation J:158523
ocular hypertelorism J:158523
short mandible J:158523
Krastm4Tyj/Krastm4Tyj
Ugdhtm1.1Xzh/Ugdhtm1.1Xzh
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * CBA/J
abnormal lacrimal gland development J:185652
absent lacrimal glands J:185652
Lgi4tm1.1Jrb/Lgi4tm1.1Jrb
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
demyelination J:158973
Lmo4tm1Sho/Lmo4tm1Sho
H2az2Tg(Wnt1-cre)11Rth/0
either: (involves: 129/Sv * CD-1) or (involves: 129/Sv * C57BL/6)
normal craniofacial phenotype J:88168
Lmx1btm1Rjo/Lmx1btm1Zfc
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S7/SvEvBrd * C57BL/6 * CBA
small cerebellum J:117035
small tectum J:117035
Lmx1btm1Rjo/Lmx1btm4.1Rjo
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S7/SvEvBrd * C57BL/6J * CBA/J
abnormal cornea morphology J:161793
abnormal corneal stroma morphology J:161793
abnormal lens epithelium morphology J:161793
ciliary body hypoplasia J:161793
corneal vascularization J:161793
decreased eye anterior chamber depth J:161793
iris stroma hypoplasia J:161793
irregularly shaped pupil J:161793
microphthalmia J:161793
Map2k1tm1Chrn/Map2k1tm1Chrn
Map2k2tm1Chrn/Map2k2tm1Chrn
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129/Sv * C57BL/6J * CBA/J * SJL
abnormal eye distance/ position J:144862
abnormal outer ear morphology J:144862
absent tongue J:144862
mandible hypoplasia J:144862
persistent truncus arteriosis J:144862
short maxilla J:144862
Map3k7tm1Mis/Map3k7tm1Mis
H2az2Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * CBA/J
abnormal craniofacial morphology J:198588
abnormal secondary palate development J:198588
cleft secondary palate J:198588
decreased cranium height J:198588
failure of palatal shelf elevation J:198588
neonatal lethality, complete penetrance J:198588
palatal shelf hypoplasia J:198588
short mandible J:198588
short maxilla J:198588
Mapk1tm1Gela/Mapk1tm1Gela
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * CBA/J
abnormal extrinsic tongue muscle morphology J:239772
abnormal mandible morphology J:239772
abnormal mandibular angle morphology J:239772
abnormal mandibular coronoid process morphology J:239772
abnormal Meckel's cartilage morphology J:239772
abnormal tongue morphology J:239772
abnormal tongue muscle morphology J:239772
cleft palate J:239772
decreased tongue size J:239772
failure of palatal shelf elevation J:239772
maxilla hypoplasia J:239772
micrognathia J:239772
neonatal lethality, complete penetrance J:239772
small mandible J:239772
small mandibular condyloid process J:239772
small Meckel's cartilage J:239772
Mapk1tm1Gela/Mapk1tm1Gela
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J
abnormal thymus morphology J:144862
abnormal thyroid gland morphology J:144862
cleft palate J:144862
double outlet right ventricle J:144862
lethality throughout fetal growth and development, complete penetrance J:144862
mandible hypoplasia J:144862
persistent truncus arteriosis J:144862
short maxilla J:144862
ventricular septal defect J:144862
Mapk1tm1Gela/Mapk1tm1Gela
Mapk3tm1Gela/Mapk3+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J
abnormal eye distance/ position J:144862
abnormal thymus morphology J:144862
abnormal thyroid gland morphology J:144862
absent tongue J:144862
cleft palate J:144862
mandible hypoplasia J:144862
persistent truncus arteriosis J:144862
short maxilla J:144862
ventricular septal defect J:144862
Mapk1tm1Gela/Mapk1tm1Gela
Mapk3tm1Gela/Mapk3tm1Gela
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J
abnormal eye distance/ position J:144862
abnormal thyroid gland morphology J:144862
absent mandible J:144862
absent outer ear J:144862
absent tongue J:144862
athymia J:144862
decreased body length J:144862
persistent truncus arteriosis J:144862
short maxilla J:144862
small pharyngeal arch J:144862
ventricular septal defect J:144862
Mapttm2Arbr/?
Runx1tm3Spe/Runx1tm3Spe
H2az2Tg(Wnt1-cre)11Rth/?
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J * CBA/J
abnormal axon morphology J:226826
abnormal sensory neuron innervation pattern J:226826
Mau2tm1.1Hpt/Mau2tm1.1Hpt
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S2/SvPas * C57BL/6 * C57BL/6J * CBA/J * SJL
abnormal craniofacial development J:213338
abnormal cranium morphology J:213338
abnormal jaw morphology J:213338
abnormal pharyngeal arch mesenchyme morphology J:213338
abnormal upper lip morphology J:213338
decreased cranial neural crest cell proliferation J:213338
eyelids open at birth J:213338
face hypoplasia J:213338
lowered ear position J:213338
short mandible J:213338
small mandible J:213338
upturned snout J:213338
Mau2tm1.1Hpt/Mau2tm1.1Hpt
Nipbltm1.1Hpt/Nipbl+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S2/SvPas * C57BL/6 * C57BL/6J * CBA/J * SJL
short mandible J:213338
Mau2tm1.1Hpt/Mau2tm1.1Hpt
Nipbltm1.1Hpt/Nipbltm1.1Hpt
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S2/SvPas * C57BL/6 * C57BL/6J * CBA/J * SJL
abnormal craniofacial development J:213338
abnormal cranium morphology J:213338
abnormal jaw morphology J:213338
eyelids open at birth J:213338
face hypoplasia J:213338
lowered ear position J:213338
short mandible J:213338
Mef2ctm1Eno/Mef2ctm1Jjs
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6J * CBA/J
abnormal craniofacial development J:122483
abnormal dermal melanocyte morphology J:173609
abnormal epidermal melanocyte morphology J:173609
abnormal head morphology J:122483
abnormal mandibular angle morphology J:122483
abnormal melanocyte differentiation J:173609
abnormal melanosome morphology J:173609
abnormal pharyngeal arch morphology J:122483
abnormal respiratory system morphology J:122483
abnormal tongue morphology J:122483
absent tympanic ring J:122483
cleft palate J:122483
cyanosis J:122483
decreased melanocyte number J:173609
decreased skin pigmentation J:173609
delayed bone ossification J:122483
mandible hypoplasia J:122483
mandibular condyloid process hypoplasia J:122483
mandibular coronoid process hypoplasia J:122483
Meckel's cartilage hypoplasia J:122483
neonatal lethality, complete penetrance J:122483
normal nervous system phenotype J:173609
short mandible J:122483
temporal bone hypoplasia J:122483
zygomatic arch hypoplasia J:122483
Megf8tm1.2Ddg/Megf8tm1.2Ddg
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S6/SvEvTac * C57BL/6J * CBA/J
abnormal axon fasciculation J:206541
abnormal ophthalmic nerve morphology J:206541
normal limbs/digits/tail phenotype J:206541
normal nervous system phenotype J:206541
Mfn2tm1Dcc/Mfn2tm3Dcc
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129 * 129S4/SvJaeSor * Black Swiss
decreased body size J:132329
impaired limb coordination J:132329
impaired righting response J:132329
postnatal lethality, complete penetrance J:132329
small cerebellum J:132329
Mrgprdtm1Mjz/?
Rettm1Ddg/Rettm1Ddg
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129 * 129S1/Sv * C57BL/6 * C57BL/6J * CBA/J
abnormal neurite morphology J:126484
MrtfbGt(RRJ478)Byg/MrtfbGt(RRJ478)Byg
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129P2/OlaHsd * C57BL/6J * CBA/J
lethality throughout fetal growth and development, incomplete penetrance J:117226
Myctm2Fwa/Myc+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S6/SvEvTac * C57BL/6 * CBA
belly spot J:121871
Myctm2Fwa/Myctm2Fwa
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S6/SvEvTac * C57BL/6 * CBA
abnormal auditory brainstem response J:121871
abnormal frontal bone morphology J:121871
abnormal malleus morphology J:121871
abnormal middle ear ossicle morphology J:121871
abnormal parietal bone morphology J:121871
absent pinna reflex J:121871
conductive hearing impairment J:121871
decreased body size J:121871
decreased body weight J:121871
short malleus manubrium J:121871
short nasal bone J:121871
short snout J:121871
small cranium J:121871
small malleus J:121871
small nasal bone J:121871
variable body spotting J:121871
Myocdtm1Msp/Myocdtm1Msp
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129/Sv * C57BL/6 * CBA
abnormal angiogenesis J:131288
abnormal vascular smooth muscle morphology J:131288
cyanosis J:131288
patent ductus arteriosus J:131288
postnatal lethality, complete penetrance J:131288
Ndst1tm1Grob/Ndst1tm1Grob
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J
normal vision/eye phenotype J:130571
Ndst1tm1Grob/Ndst1tm1Grob
Ndst2tm1Lkj/Ndst2tm1Lkj
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J
abnormal lacrimal gland development J:185652
absent lacrimal glands J:185652
Nf1tm1Par/Nf1tm1Par
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
abnormal adrenal cortex morphology J:80323
abnormal adrenal gland morphology J:80323
abnormal adrenergic chromaffin cell morphology J:80323
abnormal sympathetic ganglion morphology J:80323
normal cardiovascular system phenotype J:80323
decreased body size J:80323
enlarged adrenal glands J:80323
increased ganglioneuroma incidence J:80323
increased gangliosarcoma incidence J:80323
increased pheochromocytoma incidence J:80323
increased tumor incidence J:80323
respiratory failure J:80323
thin adrenal cortex J:80323
Nf1tm1Par/Nf1tm1Tyj
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129/Sv * C57BL/6 * CBA
abnormal neural crest cell morphology J:131914
Nfatc1tm1Glm/Nfatc1tm1Glm
H2az2Tg(Wnt1-cre)11Rth/0
Gt(ROSA)26Sortm1Sho/Gt(ROSA)26Sor+
involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * CBA
abnormal cardiac outflow tract development J:185683
Ngfrtm1.1Vk/Ngfrtm1.1Vk
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S2/SvPas * C57BL/6J * CBA/J * FVB/N
abnormal sciatic nerve morphology J:178666
normal cardiovascular system phenotype J:178666
normal growth/size/body region phenotype J:178666
limb grasping J:178666
Nipbltm1.1Hpt/Nipbltm1.1Hpt
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S2/SvPas * C57BL/6 * C57BL/6J * CBA/J * SJL
abnormal craniofacial development J:213338
abnormal cranium morphology J:213338
abnormal jaw morphology J:213338
abnormal pharyngeal arch mesenchyme morphology J:213338
abnormal upper lip morphology J:213338
decreased cranial neural crest cell proliferation J:213338
eclabion J:213338
eyelids open at birth J:213338
face hypoplasia J:213338
lowered ear position J:213338
mandible hypoplasia J:213338
maxilla hypoplasia J:213338
short mandible J:213338
small mandible J:213338
upturned snout J:213338
Notch1tm2Rko/Notch1tm2Rko
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129X1/SvJ * C57BL/6 * CBA
normal craniofacial phenotype J:181120
perinatal lethality, complete penetrance J:181120
Nrg1tm4Cbm/Nrg1tm4.1Cbm
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129P2/OlaHsd * BALB/cJ * C57BL/6J * CBA/J
abnormal gait J:199150
abnormal muscle spindle morphology J:199150
decreased muscle spindle number J:199150
impaired coordination J:199150
normal nervous system phenotype J:199150
Nubp2tm1c(EUCOMM)Hmgu/Nubp2tm1c(EUCOMM)Hmgu
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Tg(Wnt1-GAL4)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA/J
increased cranial neural crest cell apoptosis J:284772
Nubp2tm1c(EUCOMM)Hmgu/Nubp2tm1c(EUCOMM)Hmgu
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Tg(Wnt1-GAL4)11Rth/0
involves: C57BL/6
abnormal brain morphology J:284772
abnormal face development J:284772
abnormal head mesenchyme morphology J:284772
abnormal olfactory epithelium morphology J:284772
abnormal stomodeum morphology J:284772
absent nasal capsule J:284772
midline facial cleft J:284772
nasal septum cartilage hypoplasia J:284772
small frontonasal prominence J:284772
small mandibular prominence J:284772
small maxillary prominence J:284772
Pax3tm2Joe/Pax3tm2Joe
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J
normal cardiovascular system phenotype J:159124
cyanosis J:159124
decreased birth body size J:159124
hypaxial muscle hypoplasia J:159124
neonatal lethality, complete penetrance J:159124
respiratory failure J:159124
spina bifida J:159124
Pax9tm1.1Hpt/Pax9tm1.1Hpt
H2az2Tg(Wnt1-cre)11Rth/?
involves: 129S2/SvPas * C57BL/6 * CBA * SJL
abnormal maxillary shelf morphology J:125026
abnormal palatine bone horizontal plate morphology J:125026
absent alveolar process J:125026
absent mandibular coronoid process J:125026
absent premaxilla J:125026
absent teeth J:125026
aphagia J:125026
arrest of tooth development J:125026
cleft secondary palate J:125026
failure of palatal shelf elevation J:125026
neonatal lethality, complete penetrance J:125026
Pbx1tm1Koss/Pbx1tm1Koss
Pbx2tm1Mlc/Pbx2+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129P2/OlaHsd * 129S/Sv * C57BL/6J * CBA/J
cleft palate J:178316
normal nervous system phenotype J:178316
postnatal lethality, complete penetrance J:178316
Pdgfratm8Sor/Pdgfratm8Sor
H2az2Tg(Wnt1-cre)11Rth/?
involves: C57BL/6 * CBA
delayed heart development J:122584
persistent truncus arteriosis J:122584
retroesophageal right subclavian artery J:122584
ventricular septal defect J:122584
Pdgfratm8Sor/Pdgfratm8Sor
H2az2Tg(Wnt1-cre)11Rth/0
Not Specified
abnormal frontal bone morphology J:81153
abnormal frontonasal prominence morphology J:81153
abnormal nasal bone morphology J:81153
abnormal nasal capsule morphology J:81153
abnormal vasculogenesis J:81153
hemorrhage J:81153
midline facial cleft J:81153
perimembraneous ventricular septal defect J:81153
persistent truncus arteriosis J:81153
postnatal lethality J:81153
short snout J:81153
small thymus J:81153
Pdgfratm8Sor/Pdgfratm8Sor
Pdgfrbtm1Mdt/Pdgfrbtm1Mdt
H2az2Tg(Wnt1-cre)11Rth/?
involves: C57BL/6 * CBA
abnormal cardiac neural crest cell migration J:122584
abnormal thymus development J:122584
cleft palate J:122584
cyanosis J:122584
perinatal lethality, complete penetrance J:122584
persistent truncus arteriosis J:122584
retroesophageal right subclavian artery J:122584
thymus hypoplasia J:122584
ventricular septal defect J:122584
Pdgfrbtm1Mdt/Pdgfrbtm1Mdt
H2az2Tg(Wnt1-cre)11Rth/?
involves: C57BL/6 * CBA
perimembraneous ventricular septal defect J:122584
Phox2atm2.1Jbr/Phox2atm2.1Jbr
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S2/SvPas * C57BL/6J * CBA/J
normal nervous system phenotype J:157532
Phox2btm3.1Jbr/Phox2btm3.1Jbr
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S2/SvPas * C57BL/6J * CBA/J
abnormal parasympathetic ganglion morphology J:157532
Pitx2tm1.1Sac/Pitx2tm2Sac
H2az2Tg(Wnt1-cre)11Rth/?
Gt(ROSA)26Sortm1Sor/?
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * CBA
abnormal eye development J:104125
abnormal eye muscle development J:104125
abnormal eye pigmentation J:104125
abnormal optic stalk morphology J:104125
abnormal retinal pigmentation J:104125
absent optic nerve J:104125
absent sclera J:104125
anophthalmia J:104125
decreased corneal stroma thickness J:104125
Pkd1tm3Jzh/Pkd1tm3Jzh
H2az2Tg(Wnt1-cre)11Rth/?
involves: 129P2/OlaHsd * C57BL/6 * CBA
abnormal craniofacial bone morphology J:139970
abnormal perichondrium morphology J:139970
abnormal presphenoid synchondrosis J:139970
abnormal sphenoid bone morphology J:139970
decreased chondrocyte proliferation J:139970
delayed intramembranous bone ossification J:139970
domed cranium J:139970
malocclusion J:139970
maxilla hypoplasia J:139970
nasal bone hypoplasia J:139970
premature presphenoid synchondrosis closure J:139970
short frontal bone J:139970
short mandible J:139970
short maxilla J:139970
short nasal bone J:139970
short premaxilla J:139970
short presphenoid bone J:139970
short snout J:139970
Plxnd1tm1.1Tmj/Plxnd1+
Plxnd1tm1Ddg/Plxnd1+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S/SvEv * C57BL/6J * CBA/J
abnormal excitatory postsynaptic potential J:205528
normal nervous system phenotype J:205528
Plxnd1tm1.1Tmj/Plxnd1tm1.1Tmj
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * CBA/J
normal cardiovascular system phenotype J:143763
normal mortality/aging J:143763
Plxnd1tm1Ddg/Plxnd1tm1.1Tmj
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S/SvEv * C57BL/6 * C57BL/6J * CBA/J
abnormal motor neuron innervation pattern J:149553
abnormal motor neuron morphology J:149553
normal behavior/neurological phenotype J:149553
Pomt2tm1.1Hhu/Pomt2tm1.1Hhu
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * CBA/J
normal nervous system phenotype J:179356
Porcntm1.1Lcm/Porcn+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Tg(rx3-icre)1Mjam/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J * CD-1
abnormal retinal pigmentation J:218165
coloboma J:218165
microphthalmia J:218165
Porcntm1.1Lcm/Y
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J * CD-1
abnormal craniofacial development J:218165
abnormal craniofacial morphology J:218165
abnormal midbrain-hindbrain boundary morphology J:218165
cleft palate J:218165
cleft upper lip J:218165
coloboma J:218165
Porcntm1.1Lcm/Y
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Tg(rx3-icre)1Mjam/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J * CD-1
abnormal anterior eye segment morphology J:218165
abnormal craniofacial morphology J:218165
abnormal midbrain-hindbrain boundary morphology J:218165
abnormal retinal pigmentation J:218165
cleft palate J:218165
cleft upper lip J:218165
coloboma J:218165
decreased cornea thickness J:218165
failure of eyelid fusion J:218165
iris hypoplasia J:218165
Ptpn11tm1.1Rbns/Ptpn11tm1.1Rbns
H2az2Tg(Wnt1-cre)11Rth/0
B6.Cg-Ptpn11tm1.1Rbns H2az2Tg(Wnt1-cre)11Rth
abnormal aortic arch and aortic arch branch attachment J:150835
abnormal eye distance/ position J:150835
abnormal mandible morphology J:150835
abnormal nasal bone morphology J:150835
abnormal nasal capsule morphology J:150835
abnormal nasopharynx morphology J:150835
abnormal tongue morphology J:150835
absent craniofacial bones J:150835
absent mandible J:150835
absent nasal capsule J:150835
common truncal valve J:150835
decreased fetal size J:150835
lethality throughout fetal growth and development, complete penetrance J:150835
microcephaly J:150835
micrognathia J:150835
persistent truncus arteriosis J:150835
small ears J:150835
small snout J:150835
ventricular septal defect J:150835
Ptpn11tm1.1Wbm/Ptpn11tm1.1Wbm
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL * SJL/J
abnormal axon extension J:153219
abnormal axon fasciculation J:153219
abnormal craniofacial morphology J:153219
abnormal melanocyte morphology J:153219
abnormal sensory neuron innervation pattern J:153219
absent Schwann cell precursors J:153219
decreased enteric neural crest cell number J:153219
decreased Schwann cell number J:153219
decreased Schwann cell precursor number J:153219
decreased sensory neuron number J:153219
embryonic lethality during organogenesis, incomplete penetrance J:153219
Ptpn11tm6Bgn/Ptpn11+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S6/SvEvTac * C57BL/6 * CBA/J
normal cardiovascular system phenotype J:147154
decreased cranium height J:147154
increased inner canthal distance J:147154
Pygo2tm1.1Ssp/Pygo2tm1.2Ssp
H2az2Tg(Wnt1-cre)11Rth/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
small lens J:121416
Pygo2tm1.1Ssp/Pygo2tm1.2Ssp
Tg(Pax6-cre,GFP)1Pgr/?
H2az2Tg(Wnt1-cre)11Rth/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * FVB
small lens J:121416
Rarbtm2Ipc/Rarbtm2Ipc
Rargtm3Ipc/Rargtm3Ipc
H2az2Tg(Wnt1-cre)11Rth/?
involves: 129/Sv * C57BL/6 * SJL
abnormal conjunctival sac morphology J:102847
abnormal eye development J:102847
decreased periocular mesenchyme apoptosis J:102847
decreased ventral retina size J:102847
persistent hyperplastic primary vitreous J:102847
ventral rotation of lens J:102847
Resttm1.1Yasu/Rest+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJae * C57BL/6 * C57BL/6J * CBA/J
belly spot J:230341
normal mortality/aging J:230341
normal nervous system phenotype J:230341
Resttm1.1Yasu/Rest+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Tg(Dct-lacZ)A12Jkn/0
involves: 129S4/SvJae * C57BL/6 * CBA
abnormal melanoblast morphology J:230341
Resttm1.1Yasu/Resttm1.1Yasu
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJae * C57BL/6 * C57BL/6J * CBA/J
neonatal lethality, complete penetrance J:230341
normal nervous system phenotype J:230341
Resttm1.1Yasu/Resttm1.1Yasu
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Tg(Dct-lacZ)A12Jkn/0
involves: 129S4/SvJae * C57BL/6 * CBA
abnormal melanoblast morphology J:230341
Rettm1Ddg/Rettm1Ddg
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129 * C57BL/6 * C57BL/6J * CBA/J
abnormal jejunum morphology J:126484
abnormal neuron morphology J:126484
absent enteric neurons J:126484
aganglionic megacolon J:126484
distended abdomen J:126484
enlarged ileum J:126484
postnatal lethality, incomplete penetrance J:126484
small dorsal root ganglion J:126484
weakness J:126484
Rhoatm1Yuyo/Rhoatm1Yuyo
H2az2Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * CBA/J
abnormal brain morphology J:172044
abnormal midbrain development J:172044
abnormal midbrain morphology J:172044
abnormal neuron proliferation J:172044
exencephaly J:172044
increased midbrain size J:172044
increased neuronal precursor cell number J:172044
Ror1tm1.1Meg/Ror1tm1.1Meg
Ror2tm1.1Meg/Ror2tm1.1Meg
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJae * C57BL/6J * CBA/J
abnormal sympathetic neuron innervation pattern J:182150
Smotm1Amc/Smotm2Amc
H2az2Tg(Wnt1-cre)11Rth/?
involves: C57BL/6J * CBA/J
abnormal basisphenoid bone morphology J:89445
abnormal craniofacial development J:89445
abnormal cranium morphology J:89445
abnormal ethmoid bone morphology J:89445
abnormal mandible morphology J:89445
abnormal mandibular condyloid process morphology J:89445
abnormal maxilla morphology J:89445
abnormal sphenoid bone morphology J:89445
abnormal temporal bone morphology J:89445
abnormal thyroid cartilage morphology J:89445
abnormal tooth morphology J:89445
absent gonial bone J:89445
absent incus J:89445
absent lacrimal bone J:89445
absent lower incisors J:89445
absent malleus J:89445
absent middle ear ossicles J:89445
absent orbitosphenoid bone J:89445
absent palatine bone J:89445
absent presphenoid bone J:89445
absent pterygoid process J:89445
absent Reichert cartilage J:89445
absent stapes J:89445
absent styloid process J:89445
absent tongue J:89445
absent tympanic ring J:89445
absent vomer bone J:89445
Meckel's cartilage hypoplasia J:89445
nasal bone hypoplasia J:89445
nasal septum hypoplasia J:89445
short Meckel's cartilage J:89445
small alisphenoid bone J:89445
small temporal bone squamous part J:89445
small zygomatic bone J:89445
Smotm2Amc/Smotm2.1Amc
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129X1/SvJ * C57BL/6J * CBA/J
abnormal artery morphology J:135134
abnormal cardiac outflow tract development J:135134
abnormal neural crest cell apoptosis J:135134
persistent truncus arteriosis J:135134
pulmonary artery hypoplasia J:135134
transposition of great arteries J:135134
Smotm2Amc/Smotm2.1Amc
H2az2Tg(Wnt1-cre)11Rth/0
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
involves: 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J * CBA/J
decreased cardiac neural crest cell number J:135134
impaired cardiac neural crest cell differentiation J:135134
Snai1tm1Grid/Snai1tm2Grid
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * C57BL/6 * CBA
no abnormal phenotype detected J:121243
Snai1tm1Grid/Snai1tm2Grid
Snai2tm2Grid/Snai2tm2Grid
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * C57BL/6 * CBA
abnormal Meckel's cartilage morphology J:121243
abnormal secondary palate development J:121243
cleft palate J:121243
domed cranium J:121243
failure of palatal shelf elevation J:121243
frontal bone foramen J:121243
neonatal lethality, complete penetrance J:121243
short mandible J:121243
short parietal bone J:121243
Sox9tm2Crm/Sox9+
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S7/SvEvBrd * C57BL/6 * CBA
abnormal craniofacial morphology J:84790
cleft secondary palate J:84790
Sox9tm2Crm/Sox9tm2Crm
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S7/SvEvBrd * C57BL/6 * CBA
abnormal bone ossification J:84790
abnormal craniofacial bone morphology J:84790
abnormal craniofacial development J:84790
abnormal cranium morphology J:84790
abnormal hyoid bone morphology J:84790
abnormal skeleton development J:84790
absent basisphenoid bone J:84790
absent hyoid bone body J:84790
absent hyoid bone lesser horns J:84790
absent incus J:84790
absent malleus J:84790
absent Meckel's cartilage J:84790
absent nasal capsule J:84790
absent presphenoid bone J:84790
absent stapes J:84790
absent styloid process J:84790
absent thyroid cartilage J:84790
cleft secondary palate J:84790
domed cranium J:84790
neonatal lethality, complete penetrance J:84790
respiratory distress J:84790
short mandible J:84790
short snout J:84790
small mandible J:84790
Srftm1Rmn/Srftm1Rmn
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S6/SvEvTac * C57BL/6J * CBA/J
absent thyroid gland J:144862
athymia J:144862
normal craniofacial phenotype J:144862
embryonic lethality, complete penetrance J:144862
normal hearing/vestibular/ear phenotype J:144862
mandible hypoplasia J:144862
persistent truncus arteriosis J:144862
ventricular septal defect J:144862
Stat3tm2Aki/Stat3tm2Aki
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129P2/OlaHsd * 129S4/SvJaeSor
normal no abnormal phenotype detected J:226497
Stk11tm1.1Rdp/Stk11tm1.1Rdp
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S6/SvEvTac * C57BL/6J * CBA/J
abnormal axon extension J:305107
abnormal axon morphology J:305107
abnormal neuron physiology J:305107
Tbx1tm2.1Bem/Tbx1tm2.1Bem
H2az2Tg(Wnt1-cre)11Rth/0
either: (involves: 129/Sv * C57BL/6 * C57BL/6J * CBA/J * SJL) or (involves: 129/Sv * C57BL/6J * CBA/J * CD-1 * SJL)
no abnormal phenotype detected J:154590
Tfap2atm1Hsv/Tfap2atm2Will
H2az2Tg(Wnt1-cre)11Rth/0
Not Specified
abnormal facial skin morphology J:88826
abnormal foot pigmentation J:88826
abnormal frontonasal suture morphology J:88826
abnormal incus morphology J:88826
abnormal malleus morphology J:88826
abnormal nasal bone morphology J:88826
abnormal neurocranium morphology J:88826
abnormal palatal shelf fusion at midline J:88826
abnormal periorbital skin morphology J:88826
abnormal stapes morphology J:88826
abnormal tail pigmentation J:88826
abnormal zygomatic bone morphology J:88826
absent startle reflex J:88826
anencephaly J:88826
normal behavior/neurological phenotype J:88826
belly spot J:88826
broad nasal bone J:88826
normal cardiovascular system phenotype J:88826
normal cellular phenotype J:88826
decreased body weight J:88826
exencephaly J:88826
incomplete rostral neuropore closure J:88826
malocclusion J:88826
neonatal lethality, incomplete penetrance J:88826
normal nervous system phenotype J:88826
open neural tube J:88826
respiratory distress J:88826
short frontal bone J:88826
short maxilla J:88826
short nasal bone J:88826
short snout J:88826
small orbits J:88826
wide frontal bone J:88826
Tfap2btm1Rbu/Tfap2btm2Will
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J
abnormal ciliary body morphology J:234170
abnormal cornea morphology J:234170
abnormal corneal epithelium morphology J:234170
abnormal corneal stroma morphology J:234170
abnormal eye anterior chamber morphology J:234170
abnormal eye morphology J:234170
abnormal iridocorneal angle J:234170
abnormal lens epithelium morphology J:234170
abnormal optic disk morphology J:234170
absent corneal endothelium J:234170
anterior iris synechia J:234170
anterior subcapsular cataract J:234170
corneal vascularization J:234170
decreased amacrine cell number J:234170
decreased corneal epithelium thickness J:234170
decreased total retina thickness J:234170
eye opacity J:234170
fused cornea and lens J:234170
gliosis J:234170
ocular hypertension J:234170
optic nerve atrophy J:234170
optic nerve cupping J:234170
optic nerve degeneration J:234170
retinal ganglion cell degeneration J:234170
thin retinal inner plexiform layer J:234170
Tg(CAG-Bmp4,-EGFP)1Ypc/0
H2az2Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * CBA/J * CD-1
abnormal jaw morphology J:214763
abnormal secondary palate development J:214763
abnormal temporomandibular joint morphology J:214763
absent mandibular angle J:214763
absent mandibular condyloid process J:214763
absent mandibular coronoid process J:214763
absent outer ear J:214763
agnathia J:214763
cleft palate J:214763
enhanced osteoblast differentiation J:214763
eyelids open at birth J:214763
frontal bone hypoplasia J:214763
mandible hypoplasia J:214763
maxilla hypoplasia J:214763
nasal bone hypoplasia J:214763
palatal shelf fusion with tongue or mandible J:214763
palatal shelf hypoplasia J:214763
short snout J:214763
syngnathia J:214763
Tg(CAG-cat,-Ptpn11*Q97R)1Rbns/0
H2az2Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * CBA/J * FVB/N
abnormal craniofacial morphology J:153094
abnormal cranium morphology J:153094
abnormal frontal bone morphology J:153094
abnormal nasal capsule morphology J:153094
abnormal neural crest cell migration J:153094
abnormal nose morphology J:153094
cleft palate J:153094
cleft upper lip J:153094
decreased body height J:153094
decreased body weight J:153094
decreased cranium height J:153094
decreased fetal size J:153094
domed cranium J:153094
increased inner canthal distance J:153094
large anterior fontanelle J:153094
lowered ear position J:153094
ocular hypertelorism J:153094
postnatal growth retardation J:153094
postnatal lethality J:153094
short mandible J:153094
webbed neck J:153094
Tg(CAG-Otx2,-EGFP)1Eno/?
H2az2Tg(Wnt1-cre)11Rth/?
involves: C3H * C57BL/6
failure of intramembranous bone ossification J:150709
frontal bone foramen J:150709
intracranial hemorrhage J:150709
neonatal lethality, complete penetrance J:150709
Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S6/SvEvTac * C57BL/6 * CBA
abnormal aortic arch morphology J:104325
abnormal brain dura mater morphology J:86042
abnormal cranium morphology J:86042
abnormal dorsal aorta morphology J:104325
abnormal fourth pharyngeal arch artery morphology J:104325
abnormal mandible morphology J:86042
abnormal neurocranium morphology J:86042
abnormal palate morphology J:86042
abnormal parietal bone morphology J:86042
abnormal soft palate muscle morphology J:208431
absent frontal bone J:86042
absent mandibular angle J:86042
cleft secondary palate J:86042
decreased cranial neural crest cell proliferation J:86042
interrupted aortic arch J:104325
palatal shelf hypoplasia J:86042
palatal shelves fail to meet at midline J:86042
persistent truncus arteriosis J:104325
postnatal lethality, complete penetrance J:104325
retroesophageal right subclavian artery J:104325
small cranium J:86042
small mandible J:86042
small mandibular condyloid process J:86042
small mandibular coronoid process J:86042
small maxilla J:86042
ventricular septal defect J:104325
Tgfbr2tm1Karl/Tgfbr2tm1Karl
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
abnormal aortic arch and aortic arch branch attachment J:96359
abnormal blood vessel physiology J:96359
abnormal cartilage morphology J:96359
abnormal craniofacial bone morphology J:96359
abnormal hindbrain morphology J:96359
abnormal midbrain morphology J:96359
abnormal neural crest cell morphology J:96359
abnormal parathyroid gland morphology J:96359
abnormal vasodilation J:96359
absent parathyroid glands J:96359
blood vessel congestion J:96359
cleft secondary palate J:96359
congestive heart failure J:96359
palatal shelves fail to meet at midline J:96359
parathyroid hypoplasia J:96359
perinatal lethality J:96359
persistent truncus arteriosis J:96359
small thymus J:96359
ventricular septal defect J:96359
Ugdhtm1.1Xzh/Ugdhtm1.1Xzh
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * CBA/J
abnormal embryonic tissue physiology J:185652
abnormal lacrimal gland development J:185652
absent lacrimal glands J:185652
cleft palate J:185652
neonatal lethality, complete penetrance J:185652
Ugdhtm1.1Xzh/Ugdhtm1.1Xzh
Tg(Pax6-HRAS*G12V)2044Ove/0
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * CBA/J * FVB/N
normal endocrine/exocrine gland phenotype J:185652
Vgll4tm1b(EUCOMM)Hmgu/Vgll4tm1c(EUCOMM)Hmgu
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: C57BL/6J * C57BL/6N * CBA/J * SJL
normal cardiovascular system phenotype J:273437
Wlstm1.1Lan/Wlstm1.1Lan
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S/SvEv * C57BL/6J * CBA/J * SJL
abnormal metencephalon morphology J:164701
abnormal neural tube morphology J:164701
absent cerebellum J:164701
absent choroid plexus J:164701
absent midbrain J:164701
absent midbrain-hindbrain boundary J:164701
decreased forebrain size J:164701
perinatal lethality J:164701
short rostral-caudal axis J:164701
Wlstm1.1Whsu/Wlstm1.1Whsu
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S6/SvEvTac * C57BL/6J * CBA/J
abnormal brain morphology J:167835
abnormal cranial nerve morphology J:167835
abnormal craniofacial development J:167835
abnormal craniofacial morphology J:167835
abnormal hindbrain development J:167835
abnormal midbrain development J:167835
abnormal midbrain-hindbrain boundary development J:167835
abnormal neurocranium morphology J:167835
abnormal salivary gland morphology J:167835
abnormal serous gland morphology J:167835
abnormal tooth morphology J:167835
abnormal viscerocranium morphology J:167835
absent cerebellum J:167835
absent choroid plexus J:167835
absent tectum J:167835
absent tegmentum J:167835
cleft palate J:167835
Ywhaetm2.1Awb/Ywhae+
H2az2Tg(Wnt1-cre)11Rth/0
Tg(Wnt1-GAL4)11Rth/0
involves: 129S6/SvEvTac * C57BL/6J
normal pigmentation phenotype J:242528
Ywhaetm2.1Awb/Ywhae+
YwhazGt(OST432062)Lex/Ywhaz+
H2az2Tg(Wnt1-cre)11Rth/0
Tg(Wnt1-GAL4)11Rth/0
involves: 129S6/SvEvTac * C57BL/6J
belly spot J:242528
Ywhaetm2.1Awb/Ywhae+
YwhazGt(OST432062)Lex/YwhazGt(OST432062)Lex
H2az2Tg(Wnt1-cre)11Rth/0
Tg(Wnt1-GAL4)11Rth/0
involves: 129S6/SvEvTac * C57BL/6J
belly spot J:242528
normal craniofacial phenotype J:242528
decreased body weight J:242528
decreased survivor rate J:242528
premature death J:242528
Ywhaetm2.1Awb/Ywhaetm2.1Awb
H2az2Tg(Wnt1-cre)11Rth/0
Tg(Wnt1-GAL4)11Rth/0
involves: 129S6/SvEvTac * C57BL/6J
belly spot J:242528
Ywhaetm2.1Awb/Ywhaetm2.1Awb
YwhazGt(OST432062)Lex/Ywhaz+
H2az2Tg(Wnt1-cre)11Rth/0
Tg(Wnt1-GAL4)11Rth/0
involves: 129S6/SvEvTac * C57BL/6J
belly spot J:242528
Ywhaetm2.1Awb/Ywhaetm2.1Awb
YwhazGt(OST432062)Lex/YwhazGt(OST432062)Lex
H2az2Tg(Wnt1-cre)11Rth/0
Tg(Wnt1-GAL4)11Rth/0
involves: 129S6/SvEvTac * C57BL/6J
embryonic lethality, complete penetrance J:242528
YwhazGt(OST432062)Lex/YwhazGt(OST432062)Lex
H2az2Tg(Wnt1-cre)11Rth/0
Tg(Wnt1-GAL4)11Rth/0
involves: 129S6/SvEvTac * C57BL/6J
normal pigmentation phenotype J:242528
Zfpm1tm4Sho/Zfpm1tm4Sho
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S6/SvEvTac * C57BL/6 * CBA
normal cardiovascular system phenotype J:99745
Zfpm2tm1Sho/Zfpm2tm2Sho
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * C57BL/6 * CBA
normal cardiovascular system phenotype J:150452
normal mortality/aging J:150452
Zic3tm1.1Smwa/Y
H2az2Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * CBA/J
no abnormal phenotype detected J:194989
Zic3tm2.1Jwb/Y
H2az2Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6J * CBA/J
no abnormal phenotype detected J:192577

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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory