Gpr161^tm1.2Smuk
Targeted Allele Detail

Summary

• Symbol: Gpr161^tm1.2Smuk
• Name: G protein-coupled receptor 161; targeted mutation 1.2, Saikat Mukhopadhyay
• MGI ID: MGI:6357710
• Synonyms: Gpr161^fl
• Gene: Gpr161 Location: Chr1:165123358-165154314 bp, + strand Genetic Position: Chr1, 72.64 cM
• Alliance: Gpr161^tm1.2Smuk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:253972
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: An frt-lacZ-loxP-neomycin cassette-frt-loxP construct was inserted into intron 3 and a single loxP site was inserted into intron 4. FLP-mediated recombination removed the lacZ and neomycin cassette, leaving loxP sites flanking exon 4. (J:253972)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	20 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr161 Mutation: 30 strains or lines available

References

• Original: J:253972 Hwang SH, et al., The G protein-coupled receptor Gpr161 regulates forelimb formation, limb patterning and skeletal morphogenesis in a primary cilium-dependent manner. Development. 2018 Jan 8;145(1):dev154054
• All: 7 reference(s)