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Irx3tm3Hui
Targeted Allele Detail
Summary
Symbol: Irx3tm3Hui
Name: Iroquois related homeobox 3; targeted mutation 3, Chi-Chung Hui
MGI ID: MGI:5444472
Synonyms: Irx3flox
Gene: Irx3  Location: Chr8:92525139-92528282 bp, - strand  Genetic Position: Chr8, 44.55 cM
Alliance: Irx3tm3Hui page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:189007
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exons 2 to 4 were floxed via homologous recombination. (J:189007)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Irx3 Mutation:  24 strains or lines available
References
Original:  J:189007 Gaborit N, et al., Cooperative and antagonistic roles for Irx3 and Irx5 in cardiac morphogenesis and postnatal physiology. Development. 2012 Nov;139(21):4007-19
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory