Ldb1^tm1Lmgd
Targeted Allele Detail

Summary

• Symbol: Ldb1^tm1Lmgd
• Name: LIM domain binding 1; targeted mutation 1, Laboratory of Mammalian Genes and Development, Heiner Westphal
• MGI ID: MGI:2449177
• Synonyms: Ldb1^-
• Gene: Ldb1 Location: Chr19:46020009-46033653 bp, - strand Genetic Position: Chr19, 38.75 cM
• Alliance: Ldb1^tm1Lmgd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:81152
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The gene was disrupted by replacement of exons 3-9 with a PGK-neo cassette via homologous recombination. Homozygous mutant embryos were detected up to day E9.5-E10.5. (J:81152)

Expression

In Mice Carrying this Mutation:	87 assay results
In Structures Affected by this Mutation:	18 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ldb1 Mutation: 34 strains or lines available

References

• Original: J:81152 Mukhopadhyay M, et al., Functional ablation of the mouse Ldb1 gene results in severe patterning defects during gastrulation. Development. 2003 Feb;130(3):495-505
• All: 8 reference(s)